Sentences with phrase «major factors involved»

One of the major factors involved in determining how much you pay in premiums is what's on your driving record.

There are other major factors involved.

Major factors involved in this are long - term rate of return (95 %); diversification (86 %) and short - term rate of return (72 %).

The other major factor involved in ridding your fibromyalgia symptoms and taking back control of your health and your life is through your body's unique biochemistry, which we will be doing throughout, and using food and holistically balanced nutrition as our main weapons that will start winning back your confidence and your equilibrium starting from day one.

One of the factors that is certainly a major factor involved in hypertrophy is the tension on the muscle.

Timing is a major factor involved in assigning a health rating for cardiovascular disease.

The first major factor involves parenting style.

Not exact matches

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange CommFactors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

like I've said before, Wenger is simply stating that Sanchez is staying so that he can regain some leverage when it comes time to make a deal and to shift the focus back squarely on Sanchez... this is 101 tactics in PR management... the very fact that he even mentioned RVP's name speaks to the utterance arrogance of a man that believes he answers to no one... before you harshly judge Sanchez think carefully about what the ultimate intentions of both parties involved... Sanchez wants to win trophies and get paid generously for his efforts, whereas the club wants to pull the wool over our eyes once again so that we blame the player for wanting the very things we told him we wanted when we brought him in... how many times do we have to go down this road before we realize the only common factor in each of these scenarios is the club itself... trust me, if we showed any ambition Sanchez's contract demands would be much different... just like in other major sports players will take a «home town» discount if they see those in charge making a truly honest attempt to fight for the highest honours in their respective fields... that being said, if they see a team trying to make disparaging remarks about them in the press and not following through on their promises, they will likely try to make them pay a premium for their services or seek greener pastures... btw if anyone simply looks at the score versus Bayern today and thinks that even for a second that this was a deserved victory, just watch the game and judge for yourself... actually save yourself the anguish and just know that if it weren't for Cech and Martinez this could have been a repeat of our Champions League flopping or worse

We need caring dads and other men who are involved at school and at home to help kids recognize that a good education is often a major factor in propelling them to long - term success in life.

One involved more than 200 Canadian athletes from the 1984 Olympics who were assessed for three major readiness factors: mental, physical and technical.

The mechanism of this two - factor reprogramming is probably largely due to the intrinsic expression of SOX2 within human NSCs, which has been shown to a major protein involved in maintaining pluripotency in hESCs.

The other major transcription factor involved in IL - 22 production is the aryl hydrocarbon receptor (AHR), which is important not only for Il22 expression in ILC3s [28], but also for the development of ILC3s from immature precursors [29].

ApoE as a major causative factor and therapeutic target in Alzheimer's disease and other neurodegenerative disorders; small - molecule structure correctors to convert apoE4 to apoE3 and reverse the detrimental effects of apoE4 on mitochondria and the cytoskeleton; small - molecule protease inhibitors to block the formation of toxic fragments of apoE4; Plasma lipoprotein metabolism regulation involving apoE and apoB; cholesterol homeostasis modulation by lipoprotein receptors controlling lipoprotein clearance by the liver; Plasma HDL cholesterol (HDL - C) metabolism in the progression of atherosclerosis; the genetic epidemiology of the metabolic syndrome and low HDL - C levels established by the Turkish Heart Study.

While there are many physiological factors involved in female athletes» vulnerability to iron deficiency, low dietary intake of iron is a major factor.

104 Several hormetic response pathways have been identified involving enzymes (kinases and deacetylases including Sirtuins), transcription factor - regulation the expression of several major categories of proteins including chaperones, antioxidant enzymes and growth factors.

Cause of death for which inflammation may be a major determinant, but other factors could also be involved.

There are many factors involved in this seeming decline in health — increases in population, crowding, living in close proximity with animals and the resultant transmission of diseases, but certainly the change in diet was a major factor.

After adjusting for lifestyle and dietary risk factors, a major study involving 131,342 participants found that for every 3 - percent increase in plant protein the participants worked into their diets, they saw their risk for death from causes including heart disease drop by 10 percent over a 32 - year period.

What he discovered is that while there are many factors involved in the inability to lose weight, almost all the overweight and obese patients he treats have demonstrable metabolic and endocrinological dysfunctions that are major contributors to the weight challenges of these patients.

These odds do often have other factors involved such as genetics, ethnicity, bone structure, body weight, certain diseases, and some medications BUT getting enough calcium is a major player here.

Typically, a major transcription factor involved in the expression of detoxification genes known as Nrf2 remains in a dormant state in the body.

Moreover, these joint data from humans and mice provide the first evidence that neurodegenerative effects of airborne PM may involve gene - environment interactions with APOE ɛ4, the major genetic risk factor for pathological brain aging and AD.

Students of color are even more underrepresented among graduates with education majors, at least 82 percent of whom are white.65 This disparity could be related to a number of factors students of color face, including negative experiences with the public education system; 66 the additional costs and time involved for teacher credentialing; 67 or pressure from their families to seek out higher - earning and higher - status jobs and career tracks.68

There are so many factors involved in getting in the major door that I have to think a lot of the good writing in the world gets brushed aside for the John Edwards and Paris Hilton type lame adventures.

E-books sales have, in my opinion, reached the tipping point where they are a major part of the market that has to be factored in by all involved in publishing.

If you really consider your choices, and look at all the different factors involved — speed, ease of use, cost, convenience, and so on — you will see that short - term options have some major advantages.

The level of obedience the handler wishes to achieve with the dog is also a major factor in the time involved, as is the commitment to training by the handler.

A focal part of the series is public programming that involves critical discussion amongst Santa Barbara artists and arts professionals on the necessity of new or expanded arts initiatives and considering various factors that influence how these initiatives emerge and endure, notably in regions outside of major artistic centers, as in Santa Barbara.

A focal part of the series is public programming that involves critical discussion amongst Santa Barbara artists and arts professionals on articulating the necessity of new or expanded arts initiatives; and considering various factors that influence how these initiatives emerge and endure, notably in regions outside of major artistic centers, as is our town.

Finally, expense can be a major factor — they have «seen entire projects scrapped after hours and hours of work due to the expense involved.»

Yet had the US not become so closely involved, the results would have been greatly different, though there would still almost certainly have been serious conflicts — its just that these would have played out without considering the US as a major factor.

Having a house built is a one of the few major financial decisions you will make in life, and the biggest factor involved in whether it goes well or not, is how well you get along with your builder.

Given the large number of varying factors involved in controlling the path of «weather» (in n - dimensional phenomenistic space), it seems very likely that even major effects shouldn't be expected to repeat themselves.

Rignot, who was not involved in the new Cosgrove study, told Eos in an email that Minzoni's study confirms that Circumpolar Deep Water «IS the major factor» for Antarctic ice shelf melting.

My position on that is... no; the only hypothesis which has any legs involves a non-periodic factor with a major warming influence in recent decades.

The proper comparison is with conventional expectations as described in the IPCC reports is as I told you previously: the only hypothesis which has any legs involves a non-periodic factor with a major warming influence in recent decades.

It is innovations in the methods of manufacturing that are the product of such competition that produce the economies of scale, if such innovations involve high volume production using a high degree of specialization applied to every major factor of production, which is what support services do and law firms don't do.

There are three major factors that are involved in classifying a TBI.

There are other factors involved, but these are the five major ones.

Recent studies have shown that distracted driving is a major contributing factor to collisions involving teen drivers.

With the phrase «major driver - safety issues,» we are referring to the most prevalent factors involved in fatal - or serious - injury crashes, and these are listed below.

Facebook strategy involves two major factors to ponder on, Audience and Messaging, in the exact order.

There is still a trust factor involved on certain major events and issues, in tandem with their in - depth storytelling as opposed to news summaries.

This is a major risk factor, but almost no researchers have investigated either the mechanisms of transmission of risk whereby some children get involved and others resist, or the efficacy of existing programs for preventing involvement in gangs.

The role that a person has in a traumatic experience is a major factor that increases the likelihood of developing PTSD.31 Specifically, a previous study found that parents whose children underwent bone marrow transplantation might experience PTSD, largely because of their being unable to be as supportive to their children and as actively involved in their care as they were during outpatient treatments, with high stress levels and feelings of helplessness.5 Those investigators hypothesized that loss of parental roles might be a factor contributing to the development of PTSD among parents whose children undergo bone marrow transplantation.

[2] The major concerns of the approach are the processes involved in the perception, judgment, and memory of social stimuli; the effects of social and affective factors on information processing; and the behavioral and interpersonal consequences of cognitive processes.

Non-adherence to medication is a major cause of relapse in bipolar disorder.2, 3 The factors involved in non-adherence are multifaceted and occur at the individual, service delivery, and illness levels.

But, overall, growing up in a father - absent home is a major risk factor for depression in teen girls, while having an involved father is linked to fewer psychological problems.

Major research interests involve the identification of high - risk factors for adolescent substance use and other problem behaviors.