Sentences with phrase «major factors of production»

It also assumes that there are four major factors of production in an economy and that all revenues must go to one of these four sources.

It is innovations in the methods of manufacturing that are the product of such competition that produce the economies of scale, if such innovations involve high volume production using a high degree of specialization applied to every major factor of production, which is what support services do and law firms don't do.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

There are other factors at play though, and many recent studies have shown that the micro biome in our guts that is the foundation of our immune system and a major factor in hormone production is key to overall health.

Hepatic encephalopathy occurs when the liver can not remove certain toxins and chemicals, such as ammonia, from the blood.1 These toxins and chemicals then build up and enter the brain.1 Hepatic encephalopathy is one of the major complications of cirrhosis (scarring of the liver), and a leading cause of hospital re-admission due to its recurrence, despite treatment.1 It can occur suddenly in people with acute liver failure, but is seen more often in those with chronic liver disease.1 Symptoms of hepatic encephalopathy include mild confusion, forgetfulness, poor concentration and personality or mood changes, but can progress to extreme anxiety, seizures, severe confusion, jumbled and slurred speech and slow movement.1 The first step in treatment is to identify and treat any factors that cause hepatic encephalopathy.2 Once the episode has resolved, further treatment aims to reduce the production and absorption of toxins, such as ammonia.1 Generally, there are two types of medication used to reduce the likelihood of another hepatic encephalopathy episode — lactulose and rifaximin.2 However, it remains a leading cause of hospitalisations and re-hospitalisations in cirrhotic patients, despite the use of the above - mentioned standard of care treatment.

A major aspect of this process is the production of multiple angiogenic cytokines and growth factors in response to hypoxia / ischemia, which is mediated by the transcription factor HIF - 1 (hypoxia - inducible factor 1).

So one of the major questions we're exploring is whether we can find proteins that can target the transcription factors and block this excessive production.

The other major transcription factor involved in IL - 22 production is the aryl hydrocarbon receptor (AHR), which is important not only for Il22 expression in ILC3s [28], but also for the development of ILC3s from immature precursors [29].

A third factor to consider is that the gut, due to its mucin production, immune activity, and rapid turnover in cells and extracellular matrix, is a major consumer of glucose.

In terms of an increased risk of breast cancer, alcohol may promote excess estrogen production, which is a major risk factor in the development of the disease.

More specifically, leaky gut and gut integrity, an issue that has become a major clinical issue in functional medicine and clinical nutrition today, is more than just a function of diet, hydrochloric acid / enzyme production, microflora, and the numerous other factors upon which we typically focus.

One of Gerwig's high school drama teachers, Ed Trafton of the all - boys Jesuit High School — which invites students from her alma mater, the all - girls St. Francis, to participate in their stage productions, and vice versa — recognized her «it» factor nearly 20 years ago when she was a bespectacled, Converse - wearing Dorothy in a student production of The Wonderful Wizard of Oz, speak - singing «Over the Rainbow» to his solo piano accompaniment in the key of A-flat major.

If the extremely promising low cost thin - film technology that is entering high - volume production this year by companies like Nanosolar (100 million in venture capital from the likes of Sergey Brin) pans out, then solar could quickly become a major factor in energy production.

Brown said the availability of water is a major limiting factor to grain production, along with land.

The ambient temperature in which a tree grows is not a major factor in the production of growth - rings of differing dimensions.

The worksheets available below constitute the details each entity's production of oil & NGLs, natural gas, coal, and cement from as early as 1854 to 2010, as well as additional sources of emissions (such as vented CO2, flared CO2, own fuel use, and vented or fugitive methane), non-energy uses of oil, gas, and coal, emission factors for each fuel, calculation of emissions attributed to each Carbon Major producer, and several summary worksheets by fuel and for cumulative emissions by all entities.

Major Assumptions Calculating Carbon Emissions: Emissions Factors Coal: 0.795 tons C02 / MWh LNG: Total: 0.474 tons / MWh Combustion: 0.362 tons / MWh Transportation: 0.106 tons / MWh (This includes both liquification and regasification of LNG) Japan's current total carbon emissions: 1,222 million metric tons Japan's total nuclear production in 2009 was calculated by summing yearly generation from each of Japan's reactors in 2009.