Sentences with phrase «major gene effects»

It was assumed that if the data sets had a normal residual distribution when fitting the polygenic models, normality was maintained when the models were extended to include the major gene effects.

150/5: 45 NLRP2: A paternally - imprinted gene implicated in innate immunity and blastocyst development has a major gene effect on endometriosis.

Not exact matches

Variants of one gene had a major effect on rapid changes in beak size after a drought, researchers report in the April 22 Science.

«One of Hlusko's goals is to detect and identify a few of these genes with major effects on variation in tooth size and shape in general.

«One of Leslea's goals is to detect and identify a few of these genes with major effects on variation in tooth size and shape in general.

However, like most gene transfer approaches a major concern with ZFN technology is the potential for oncogenesis due to off - target effects.

September 1, 1996 Researchers narrow hunt for diabetes - causing gene Chicago researchers narrowed the search for a gene that has a major effect on non-insulin-dependent diabetes mellitus, or NIDDM, in Mexican Americans.

Single loci with major effects in fire ants: the effects of the complementary sex - determining locus and the green beard supergene on gene expression

This in turn suggested that the genes controlling their immune system's responses (located in the major histocompatibility complex [MHC]-RRB- might be responsible for the side effects they were experiencing.

This auto - feedback system has been proposed as a feature of robustness, i.e. minor perturbations to the system will not produce major effects on gene transcription.

Further, we show that the remarkable diversity of form in the dog, in contrast to some other species studied to date, appears to have a simple genetic basis dominated by genes of major effect.

It seems that one major effect of the fast idea (along with the activation of many protective genes) is the lowering of an important chemical in our bodies Insulin like growth Factor, IGF.

Moreover, these joint data from humans and mice provide the first evidence that neurodegenerative effects of airborne PM may involve gene - environment interactions with APOE ɛ4, the major genetic risk factor for pathological brain aging and AD.

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It is, therefore, no surprise that a number of genetic studies have been performed in this breed, with results proposing a single major gene with a large effect on seizures 8, 24 - 26.

HSF4 is a gene of major effect for this trait.

Ultimately he discovered that the recessive nature of the disease is due to a single gene of major effect that causes choroidal hypoplasia, the primary CEA defect.

However, it is possible that some genes of major effect may usually, but not always, be present in affected dogs.

The favourable allele A1 was dominant in every breed, based on the negative estimates of the dominance effect d at the major gene.

Allele effects at the major gene revealed close to complete dominance for HD and ED in each breed, and possibly a slight overdominance for HD in the German Shepherd (Tables 1, 2, 3 and 4).

An effect of a major gene genotype was added to the polygenic models to analyse the existence of a major gene.

Allelic effects at the major gene locus showed nearly to complete dominance, with a recessive, unfavourable allele in both traits.