Sentences with phrase «major histocompatibility complex»

When the team looked at what gene signatures the RORγt - dependent ILCs expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display foreign proteins to the immune system and directly interact with T cells.

HLA - B7 and β2 microglobulin are components of major histocompatibility complex class I (MHC - I), expression of which is often altered during cancer progression, allowing tumor cells to evade the immune system.

FcRn bears an intriguing structural resemblance to molecules called major histocompatibility complex (MHC) proteins, which function in the vertebrate adaptive immune response by presenting antigenic peptides to T cells.

This haplotype has sequence similarities to human major histocompatibility complex alleles associated with susceptibility to type 1 diabetes (89).

The G9a gene in the human major histocompatibility complex encodes a novel protein containing ankyrin - like repeats

They've been bred to lack proteins — members of a family called MHCI (which stands for major histocompatibility complex class I)-- crucial to fighting pathogens.

Antigens are exposed on the surface of DCs in a protein complex along with major histocompatibility complex (MHC) proteins that mediate the recognition and activation of the appropriate T cell subtype.

She received her Ph.D. in Biochemistry from the University of Wisconsin - Madison and was a postdoctoral fellow at The Scripps Research Institute and the University of Dundee, Scotland, where her research focused on the intracellular transport of major histocompatibility complex molecules and invariant chain.

Association of hypothyroid disease in Doberman Pinscher dogs with a rare major histocompatibility complex DLA class II haplotype.

Unconventional T cells are defined by their capacity to respond to signals other than the well - known complex of peptides and major histocompatibility complex proteins.

Thymic major histocompatibility complex antigens and the αβ T - cell receptor determine the CD4 / CD8 phenotype of T cells.

Individual body odor is influenced by genes, and by one group in particular: the genes that determine which proteins combine to form your unique major histocompatibility complex (MHC).

A majority of T cells bearing the αβ T cell receptor (TCR) are specific for peptides bound to polymorphic classical major histocompatibility complex (MHC) molecules.

The laboratory focuses on understanding the mechanism of peptide selection for immune recognition by major histocompatibility complex (MHC) molecules.

In addition, we show that MAIT cells are selected and / or restricted by MR1, a monomorphic major histocompatibility complex class I - related molecule that is markedly conserved in diverse mammalian species.

Class II Major Histocompatibility Complex Transactivator (CIITA) Inhibits Matrix Metalloproteinase - 9 Gene Expression

Major histocompatibility complex haplotypes (Kennedy et al. 2006) and cytokines (Short et al. 2009; Short et al. 2007) have also been implicated in canine diabetes.

The famous T - shirt study by Claus Wedekind shows that the pheromones we find most sexy are from people most genetically different from us (on the immune system major histocompatibility complex).

Genetic compatibility in long - term intimate relationships: partner similarity at major histocompatibility complex (MHC) genes may reduce in - pair attraction.

In this study, the SIgN team discovered for the first time that the integrity of p53 affects the production of a special cell surface protein called Major Histocompatibility Complex (MHC) class I. MHC class I molecules on the cancer cell surface serve as targets for the immune system.

Major histocompatibility complex alleles, sexual responsivity, and unfaithfulness in romantic couples

A team led by neuroscientist Carla Shatz was running a routine procedure designed to identify genes regulated by neuronal firing when an unexpected one popped up that codes for major histocompatibility complex (MHC) class I molecules, which play a crucial role in helping the immune system recognize invading pathogens.

Detecting site - specific physicochemical selective pressures: applications to the Class I HLA of the human major histocompatibility complex and the SRK of the plant sporophytic self - incompatibility system Sainudiin, R., W. S. W. Wong, K. Yogeeswaran, J. B. Nasrallah et al. 2005.

Additionally, the proteasome regulates cell - cycle, antigen processing through class I major histocompatibility complex molecules, gene expression, and cell signaling (43).

The molecule in question, known as beta - 2 microglobulin, or B2M, is a component of a larger molecule called MHC I (major histocompatibility complex class I), which plays a major role in the adaptive immune system.

In this case what is being sensed is the Major Histocompatibility Complex.

The findings do not support earlier contentions that genes for T - cell receptors are linked to the Ig heavy chain locus (mouse chromosome 12) or to the major histocompatibility complex (mouse chromosome 17).

A porcine class I major histocompatibility complex (SLA) gene has been introduced into the genome of a C57BL / 10 mouse.

The major histocompatibility complex (MHC) is a region of DNA vital to the immune system.

Expression of a microinjected porcine class I major histocompatibility complex gene in transgenic mice

Burger et al. showed that cryptic female choice may play a role in a well - known mechanism of mate choice, major histocompatibility complex (MHC) matching.

Major histocompatibility complex class II (MHC II) molecules capture peptides within the endocytic pathway to generate T cell receptor (TCR) ligands.

Yet of maybe even greater gene - spreading significance is the ability to tell differences in MHC — the major histocompatibility complex, a gene family linked to the immune system and body scent.

Host genes of the major histocompatibility complex (the genes that determine how mammals respond to pathogens) play a significant role in how the immune system responds to all pathogens.

Unlike CD8 + DCs that express the cell surface protein CD205, CD8 — DCs, which are positive for the 33D1 antigen, are specialized for presentation on major histocompatibility complex (MHC) class II.

The region of chromosome 20 associated with sarcoid development is within a portion of the genome responsible for immune function called the Major Histocompatibility Complex (MHC) class II region.

How it hides: In a normal cell, genes encode instructions for surface proteins known as the major histocompatibility complex (MHC).

These molecular identity cards are produced by a set of genes collectively known as the major histocompatibility complex, or MHC.

To this aim, the researchers incorporated molecules into the scaffolds that are known as the major histocompatibility complex (MHC) and that presented small peptides derived from viral proteins to T cells.

Researchers from Princeton University and the University of California - San Diego (UCSD) recently found that an immune - system protein called MHCI, or major histocompatibility complex class I, moonlights in the nervous system to help regulate the number of synapses, which transmit chemical and electrical signals between neurons.

They looked specifically for genes coding the major histocompatibility complex (MHC)-- a molecule found on the surface of cells that acts as a crucial component of the immune systems of most vertebrates.

The immune system recognizes transplanted organs as foreign tissue by telltale proteins, called the major histocompatibility complex (MHC), that coat cell surfaces.

The team discovered each animal emits an intense odor that broadcasts the chemical composition of what is known as their major histocompatibility complex, or MHC, genotype.