Globally, harmful alcohol use is
a major modifiable contributor to the burden of disease.1 The typical age of initiation of alcohol use is around mid-adolescence and for a significant minority of adolescents their alcohol use will result in substantial harms, the most costly of which is alcohol use disorder (AUD).2 Defined as a cluster of symptoms indicating continued alcohol use despite significant problems, AUD is common and imposes a significant burden on the individual, their family and the wider society.
Treatment needs to be targeted at
major modifiable risk factors and its outcome measured objectively.26 It should preferably be at an early age as conduct disorder can be reliably detected early, 5 has high continuity, 27 is amenable to treatment at a young age, 4 and is very hard to eradicate in older children.28 In this section I discuss interventions for general aggressiveness only in children under 12; interventions targeting youth crime have been excellently reviewed by Farrington.29
«Elevated LDL cholesterol has been definitively established as
a major modifiable cardiovascular risk factor,» he said.
Researchers studied population attributable risk (PAR) changes for the five
major modifiable cardiovascular risk factors — high cholesterol, smoking, high blood pressure, obesity, and diabetes.
Prof Storey concluded: «Air pollution should be considered one of
the major modifiable risk factors to prevent and manage cardiovascular disease.
Not exact matches
Mitchell EA, Taylor BJ, Ford RPK, et al. «Four
modifiable and other
major risk factors for cot death: the New Zealand Study».
Four
modifiable and other
major risk factors for cot death: the New Zealand study.
«If the absolute risk increases of 1.51 percent for in - hospital mortality and 3.54 percent for
major postoperative complications were
modifiable, they would be consistent with the number needed to treat of 59 patients for in - hospital mortality and 28 patients for
major postoperative complications.
She said, «Obesity is a
major and
modifiable risk factor for heart disease, the leading cause of death in the United States for both men and women.»
Three main risk factors make up 85 % of the
modifiable risk for heart disease in men and women: high cholesterol, high systolic blood pressure and smoking, with high systolic blood pressure being the
major risk factor.