Researchers are also trying to determine if certain genes or other factors might
make some Zika patients more likely to develop GBS.
Experiments in cells and mice suggest that a previous exposure to dengue or West Nile can
make a Zika virus infection worse.
New York City health officials are gearing up to
make Zika blood tests available to pregnant women who have traveled to countries where the mosquito - borne disease is flourishing.
A single genetic mutation
made the Zika virus far more dangerous by enhancing its ability to kill nerve cells in developing brains, a new study suggests.
An extensive investigation of that epidemic by CDC concluded that 73 % of the population was infected, an impressive number that suddenly
made Zika an emerging pathogen to watch.
Scientists now think environmental changes
made Zika explode into a global crisis
Even if data showing superiority of Singleplex were accurate, the investigators say the 39 % «overstates the potential impact» of missed cases; clinicians use the test as only one indicator when
making a Zika diagnosis, and if that's factored in, the missed cases drop to a maximum of 12 % even with the most discrepant tests.
Global warming leads to much quicker spread of the Zika virus because the increased temperature, «makes mosquitoes mature faster,... bite more due to having a higher metabolism, and
makes the Zika virus inside of them incubate faster.»
Not exact matches
By last May,
Zika had
made its way to Brazil.
To date, travel - associated cases
make up the vast majority of
Zika infections in U.S..
Edwards said it was up to individuals to
make up their own minds about
Zika, but he is still optimistic for the games.
So let's add that to the
Zika virus, the open sewer of a harbour where the sailors and triathletes will compete, the street crime that has already
made a victim of an Australian para-athlete and the financial and political chaos that includes a president facing impeachment, many other politicians facing indictments and the declaration of a «state of public calamity» in Rio de Janeiro, with a top state official adding that it is on the verge of «social collapse.»
Here's some of what's going on in the health care world as we head into Easter weekend: payers are pushing back against PTC Therapeutcics» controversial Duchenne muscular dystropy drug; insurers are cautiously lauding new rules for Obamacare's marketplaces; a fascinating lawsuit in Arkansas explores the ethics of drug
making; and a new test for
Zika virus can produce results within an hour.
The company's Gene - RADAR system can be used at the actual hospitals where patients go; it's portable,
making it an especially convenient system for
Zika virus testing since blood samples don't have to be shipped off to diagnostic labs.
Climate change is set to
make Miami warmer and wetter for more of the year,
making the region an even more friendly home for mosquitoes, some of whom could bear diseases like
Zika, Yellow Fever and Dengue.
The White House will redirect more than half - a-billion dollars from its cache of Ebola funds to address the emerging
Zika threat because the mosquito - borne virus is likely to soon
make its way to the United States.
Susan Donelan, assistant professor of epidemiology at Stony Brook University, says she's not worried about infected mosquitoes
making their way up from South America, but of people who have been bitten and carrying
Zika making their way back to the area.
At 10:30 a.m., state AG Eric Schneiderman will
make an announcement on so - called «
Zika - prevention» products, 120 Broadway, 25th Floor, Manhattan.
At 10 a.m., NYC Mayor Bill de Blasio will appear live on WNYC's the Brian Lehrer Show to discuss Queens Boulevard,
Zika preparedness,
making Stonewall Inn a national monument and other topics.
Rep. Carolyn Maloney
makes the case for dedicated funding from to combat the spread of
Zika.
Many people might not have heard of the Aedes aegypti mosquito until this past year, when the mosquito, and the disease it can carry —
Zika — began to
make headlines.
Those mice actually die from
Zika infection,
making it difficult to study the natural transmission of the virus from father and mother to fetus and to assess the effect of this transmission on the newborns.»
(Before chopping,
Zika's 10 proteins are
made as one long protein.)
Bulstrode says the South American epidemic has shown that
Zika infection is usually mild in adults,
making it fairly safe for anyone who isn't pregnant.
This vaccine would include a circular plasmid of DNA with the genes of specific proteins of the
Zika virus inserted into it, and its effect will be similar to that of an inactivated vaccine —
making the virus unable to copy itself.
Blood from people affected by the 2014
Zika outbreak in French Polynesia provides the first evidence that the virus can
make the immune system attack nerve cells
In a third study reported in Nature, researchers from more than two dozen institutions followed a trail of genetic clues to determine when and how
Zika made its way to Florida.
In light of the Ebola delays, this week, the Science family of journals joined other scientific publishers in a statement pledging to
make all their papers about the
Zika virus freely available.
Few accounts linking
Zika and the autoimmune disease have
made it into the peer - reviewed literature.
As
Zika becomes more widespread, the risk grows that an American traveler could bring it back to the U.S. and fuel a local outbreak or even — although much less likely — that infected mosquitoes may
make their way overland to the U.S.. For his part, the infected tourist likens his experience with
Zika to a «tough flu that kicks your ass,
makes your muscles sore and Advil barely
made a dent.»
But that outbreak also complicates the picture for the Guillain — Barré /
Zika link: There did not appear to be a surge in cases of Guillain — Barré — or at least none that
made it into official reports.
Upstate Medical University researcher Anna Stewart Ibarra, Ph.D., M.P.A., and her colleagues have created a mathematical model that can serve as a guide to
make monthly predictions on when people are at greatest risk for contracting mosquito - borne viruses, such as dengue,
Zika and chikungunya, due to climate conditions.
The researchers tested that idea by infecting newborn mice (which developmentally resemble a human fetus) with different lab -
made versions of
Zika.
They discovered the S139N swap caused the most severe clinical outcomes but they also note other modern
Zika virus strains without this mutation (some occurring in the wild and others that were lab -
made) could also cause mild microcephaly and other cellular harm to mice.
If history repeats itself, the U.S. media will
make a whoop dee doo out of the first confirmed case of
Zika virus transmission that takes place in the United States from a mosquito to a person.
All of the unknowns
make it hard to predict when
Zika will reemerge.
The researchers suggest El Niño created ideal conditions for
Zika - carrying mosquitos to breed and
make more copies of the
Zika virus.
By contrast, the new
Zika candidate vaccine uses tiny strands of RNA that hold the genetic codes for
making viral proteins.
An association between
Zika infections during pregnancy and the birth of babies with microcephaly (a birth defect in which an infant's brain does not develop properly resulting in a smaller than normal head) was first suggested by Brazilian physicians in August 2015, and in November microcephaly cases potentially associated with
Zika started to be recorded; three months later WHO
made its announcement.
The structure of
Zika virus is similar to other known flavivirus structures, except for the ~ 10 amino acids that surround the Asn154 glycosylation site in each of the 180 envelope glycoproteins that
make up the icosahedral shell.
Although the World Health Organization ended its global health emergency on
Zika last November, the virus could still
make a comeback as temperatures get warmer and mosquito season ramps up.
Although scientists have
made progress in their understanding of the virus and its mosquito carrier, and are working toward treatments and a preventive vaccine, it would be premature to think that the
Zika pandemic is now under control and will not reemerge, perhaps more aggressively, say leaders from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
Discussion of people fighting the spread of
Zika virus and other exotic diseases — big threats despite their minuscule size —
makes the book especially timely.
Although scientists have
made progress in their understanding of the virus, it would be premature to think that the
Zika pandemic is now under control and will not reemerge, perhaps more aggressively, say experts.
Zika made international headlines when it was linked to an epidemic of babies born with microcephaly in Brazil.
He is also developing mirror - image versions of peptides that work against the Dengue and
Zika viruses in order to
make them more durable in the bloodstream.
«I think it is more likely doctors will start seeing men with symptoms of low testosterone, and they will work backward to
make the connection to
Zika.»
The researchers found that
Zika targeted two specific cell types in mice: spermatogonia, which
make sperm, and Sertoli cells, which are involved in helping sperm develop and sheltering them from the blood and immune system, building what's called the blood - testis barrier.
People who have antibodies to dengue might mount a less intense immune response to
Zika, which might
make it more likely that the virus crosses the placenta and infects a fetus.
The second vaccine is
made from a purified, inactivated
Zika virus that recently circulated in Puerto Rico.