Normally, males don't
make aromatase; it's silent.
Not exact matches
But in their tests, the presence of testosterone
made RORA less active, leading to a decline in
aromatase and a buildup of even more testosterone.
The mineral zinc is also known to inhibit the
aromatase enzyme, so
making sure to meet your daily requirements of zinc can be helpful for restoring normal levels of testosterone.
More estrogen can
make you more insulin resistant, especially if you're a guy and then more insulin increases
aromatase, which will take your testosterone and bring it downstream to estrogen.
Breast cancer specialists are so concerned about all the estrogen women
make after menopause that they now use drugs to block the
aromatase enzyme.
Even with ovaries removed, women
make estrogen, primarily by an
aromatase enzyme in body fat and breasts that converts an adrenal hormone, androstenedione, into estrone.
Insulin resistance raises
aromatase activity, the enzyme in charge of
making estrogen.
That's why the incidence of breast cancer is going up in men when they're exposed to certain estrogenic chemicals on the job, but also there can be epigenetic changes of the
aromatase genes that
make you more prone to not being able to do a good job of rinsing your hormones especially estrogen out of your breast.
Then a special protein found in muscle and fat cells throughout your body
makes an enzyme called
aromatase, which changes androgen into estrogen.
I am trying to disentangle hormone / hormone receptor effects, this bit is
made as simple as possible; Test - > E2 (
Aromatase) Test - > DHT (5α - reductase) DHT - > 3,17 diol (three known enzymes) E2 is a agonist to ERa, ERb1 to Erb5; Tissue specific distribution.