Sentences with phrase «makes blood stem»

Normally, the bone marrow makes blood stem cells that develop into mature blood cells over time.

In a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxic.

The problem with making blood stem cells proliferate outside the body is that the artificial growth gives rise to an accumulation of abnormal proteins in a part of the cell called the endoplasmic reticulum, ER.

\ n \ n «It?s still not clear how the cells sense shear stress, and researchers are trying to unravel the chain of events between mechanical force and stem cell production in order to manipulate the process to make blood stem cells for transplant.»

Not exact matches

Cuomo holds his father and his legacy in a sacrosanct state, making the kicker of the letter a real punch to the solar plexus and will do little to advance either man's relationship (part of this bad blood may stem from way back in 2010, when then - Attorney General Cuomo settled with the lobbying firm Faso worked for as part of a major pay - to - play pension fund scandal).

The stem cells are a particular type, called hematopoietic stem cells, that make blood cells.

But the factor that may make the discovery very significant is that umbilical cord blood can be saved, stored and multiplied without any of the ethical dilemmas facing embryonic stem cell use, which are derived from human fetuses.

Bone marrow transplants are sometimes needed to treat immune diseases that attack these stem cells, or in certain types of anaemia, in which the body can't make enough blood cells or clotting factors.

Blood cells made by the donor stem cells inside the implant were able to get into circulation where they mixed with the host's own blood cBlood cells made by the donor stem cells inside the implant were able to get into circulation where they mixed with the host's own blood cblood cells.

Also, researchers could carefully select which blood types to culture with each batch of stem cells, creating stockpiles of needed blood products for people with extremely rare blood types whose blood cell makeup makes it challenging to find good blood matches for transfusions because they would reject most other types of blood.

The French researchers hope that using freshly created blood cells made from stem cells could help alleviate those iron buildup concerns.

Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AStem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and Astem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.

Jun Takahashi at Kyoto University, Japan, and colleagues wondered whether they could treat monkeys with a disease like Parkinson's using induced pluripotent stem cells, which are made by coaxing blood or skin cells into becoming stem cells.

Through gene therapy, researchers engineered blood - forming stem cells (hematopoietic stem / progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV - infected cells.

In another surprise, NIH located two embryonic stem cell groups in India: one at Reliance Life Sciences in Mumbai, which makes new blood products; the other at the National Center for Biological Sciences in Bangalore.

These so - called hematopoietic stem cells (from Greek meaning «to make blood») have been reliably used over the past 40 years to seed bone marrow transplants in the treatment of some cancers and immune disorders.

All it took to make pluripotent stem cells, they reported, was briefly bathing blood cells from newborn mice in a mildly acidic solution and then tweaking the culture conditions.

We can also make central nervous system cells, as the blood to neural conversion technology we developed creates neural stem cells during the process of conversion.»

Bone marrow from the p16 - deficient mice made 3 times as many blood - forming stem cells as bone marrow from the normal mice did.

The results make it clear, says stem - cell biologist Amy Wagers, who headed the study, that these hematopoietic stem cells can do a lot for blood diseases but not for diseases affecting other kinds of cells.

Within bone marrow, stem cells can differentiate into mature blood cells or self - renew, meaning make more stem cells.

The results, published online today in the Proceedings of the National Academy of Sciences, suggest that lacing the grafts with stem cells enhances blood flow and boosts the production of molecules that make and maintain erections, all of which makes for a better penis reconstruction.

They found that there was no measurable difference between the concentrations of stem cells in the various samples, despite the fact that the in vivo sample was part of a dynamic environment — which included enzymes and blood flow — making it easier for the stem cells to migrate away from the target site.

Now a team has used stem cells from human cord blood to make cells that produce EPO.

To make the cells, Sundberg first created induced pluripotent stem cells from patients» blood cells or skin cells, then differentiated these into neural progenitor cells and finally Purkinje cells.

Adult stem cells keep dividing throughout life to make various kinds of cells, like new blood cells and germ cells.

To solve that problem, the researchers started with patients» blood cells and reprogrammed them into so - called induced pluripotent stem cells, which can make any other cell in the body and grow indefinitely in the laboratory.

Cheng notes that to become medically useful, the technique of growing blood cells from stem cells will have to be made even more efficient and scaled up significantly.

stem cell Special cells in the body that can make any of several different types of new cells, including blood cells.

For the other adult patients that might still benefit from a cord blood donor, either two cord blood units are combined for a single transplant, or more recently, there are some exciting new graft engineering technologies that are emerging to expand stem or progenitor cells in the laboratory before infusion or modify the cells in some way to make them more potent at the time of transplant.

Doctors can treat a patient by first getting rid of the faulty blood - making stem cells and replacing them with new ones.

Over the years researchers have been making aggregates of embryonic stem cells to obtain certain cell types, for example red blood cells.

Dr. Sadelain has made major contributions to the generation and optimization of CAR T cells to treat cancer, as well as the development of stem cell therapies for blood disorders.

Normally, the bone marrow makes stem cells (immature cells) that become three types of mature blood cells:

«However, the unexpectedly large proportion of maternal blood cells in the fetus made us think that perhaps it was the maternal, rather than the fetal, immune response that poses the real barrier to effective stem cell transplantation.»

In that condition, stem cells collected from the blood or bone marrow could be removed from a patient, edited in the lab to correct the DNA typo — a process called «ex vivo» gene editing — and then reinjected to proliferate and make a patient healthy.

Human embryonic stem cells have the remarkable capacity to mature into all of the 200 kinds of cells that make up the human body: skin, bone, nerve, blood, heart, and so on.

Each MPN is a different condition, but they are thought to be caused by an abnormal cancer stem cell that may have acquired genetic mutations that make it unable to produce blood cells normally

Cedars - Sinai scientists can harvest cells from the blood or skin of an individual and reprogram them into induced pluripotent stem cells, which can be made into any organ cell (such as those from the lung, liver or intestine), each bearing the unique genetic fingerprint and characteristics of the person.

A team led by Young - sup Yoon, MD, PhD developed a new method for generating endothelial cells, which make up the lining of blood vessels, from human induced pluripotent stem cells..

The Salk scientists now plan to make blood cells from the repaired stem cells and test their effectiveness in animals.

Stem cell researchers at Emory University School of Medicine have made an advance toward having a long - lasting «repair caulk» for blood vessels.

The stem cell makes immature blood cells.

Researchers at Boston Children's Hospital have, for the first time, generated blood - forming stem cells in the lab using pluripotent stem cells, which can make virtually every cell type in the body.

Standardize and scale up production of identical induced pluripotent stem (iPS) cells, which are stem cells made from an individual's own skin or blood cells.

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The role of these stem cells is to activate areas of the body with low blood flow (bones, tissues, ligaments, and cartilage) which makes it difficult for the body to heal and repair naturally.

In terms of fat - derived stem cells, progress has been made in several areas of canine health, including muscle inflammation and a disease known as immune - mediated anemia, which is when the immune system destroys red blood cells, leaving your dog weak and listless.

Meanwhile, Dr. Mick Bhatia's group at the Stem Cell and Cancer Research Institute at McMaster University found a way to make human skin cells sing «Any Way You Want Me,» turning directly into blood cells without a pluripotent cell step in between.