Sentences with phrase «makes fibrils»
When myocilin goes wrong, or «misfolds,» it makes fibrils that damage tissue called the trabecular meshwork that normally allows the fluid inside the eye to drain and relieve interior pressure.
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To create a new bioink, Gatenholm's team mixed polysaccharides from brown algae and tiny cellulose fibrils from wood or made by bacteria, as well as human chondrocytes, which are cells that build up cartilage.
A number of non-structural screening attempts have been made to identify natural and synthetic compounds that might prevent the aggregation and toxicity of amyloid fibrils.
«They all exhibit variations of their secondary structure — describes Iban Amenabar, who performed the nanospectroscopy experiments -; viruses and ferritin are mainly made of alpha - helical structures, while insulin fibrils are mainly made of beta - sheet structures.»
She says that these findings also have implications for designing treatments for Parkinson's, noting that some drugs currently under development are focused on getting rid of larger fibrils that make up Lewy bodies.
In the current study, Lasmézas and her team looked at cell cultures of neurons that were induced to accumulate fibrils made of misfolded α - synuclein, mimicking Lewy bodies in patients with Parkinson's.
New developments in methods made it possible to measure a network of distances between the atoms in the protein molecules that make up a fibril.
In recent years, scientists made the surprising discovery that seminal fluid harbors fragments of proteins that clump together, forming structures called amyloid fibrils.