Sentences with phrase «making abnormal cells»

«If centrioles aren't there to aid proper chromosome segregation, p53 acts as backup to prevent making abnormal cells.

Not exact matches

The cancerous cells win out over the healthy blood cells in the bone marrow, which in turn leads to kidney problems when the cancer cells make abnormal proteins instead of antibodies.
Those made with iPS cells, by contrast, tend to accumulate mutations and suffer abnormal patterns of gene activation.
Plants grown from these cells make abnormal versions of messenger RNA, the molecule used to make the proteins.
In this study, we found that chloroquine not only has an effect on the growth of the cancer cells, but also makes the tumor environment less aggressive by normalizing the abnormal blood vessels in the tumor,» says Patrizia Agostinis.
«One of the major and immediate downstream effects of myc activation is a dramatic increase in the capacity of affected cells to make protein,» Ruggero said «This, in turn, leads to increased cell survival and proliferation, and to unstable genomes that foster additional mutations that turn these abnormal cells into tumor cells
In earlier studies, Ruggero found that myc not only drives protein production, but also that myc - driven cancer cells become absolutely dependent upon this ability to make abnormal amounts of protein.
Of particular interest are the emerging techniques for genomics and proteomics, which allow profiles of gene expression and protein synthesis to be produced and comparisons to be made between normal and abnormal cells, as well as between cells before and after exposure to medicines or toxic chemicals.
The new study revealed that pancreatic cancer cells not only send signals that make macrophages produce abnormal amounts of dectin - 1 surface receptors, but also that make tumor cells themselves express high levels of galectin - 9.
The problem with making blood stem cells proliferate outside the body is that the artificial growth gives rise to an accumulation of abnormal proteins in a part of the cell called the endoplasmic reticulum, ER.
A form of non-Hodgkin lymphoma, follicular lymphoma develops when the body starts making abnormal B - cells, which are white blood cells that in normal conditions fight infections.
The inability of cells to differentiate makes them vulnerable to genetic mistakes that drive cancer, since more «stemness» means a tendency toward rapid, abnormal growth seen in tumors.
The diagnosis of multiple myeloma is made by the presence of elevated abnormal plasma cells in the bone marrow.
In this type of plasma cell neoplasm, less than 10 % of the bone marrow is made up of abnormal plasma cells and there is no cancer.
The abnormal plasma cells make M protein, which is sometimes found during a routine blood or urine test.
Each MPN is a different condition, but they are thought to be caused by an abnormal cancer stem cell that may have acquired genetic mutations that make it unable to produce blood cells normally
He took advantage of an observation made by Alfred Goldberg of Harvard Medical School, who had shown that extracts of immature red blood cells require ATP to break down abnormal proteins.
Like caffeine, stress elevates cortisol levels, which suppresses the immune system, making it harder for your body to fight infection and get rid of cells that have become abnormal.
These free radicals are generated in the body due to abnormal metabolism or improper physiological function and they start damaging cells responsible for maintaining immunity of the body, thus lowering the immunity level and making the body prone to infections.
Although there is still a lot to learn about pathogenesis (the mechanism by which a disease is caused) of Alzheimer's yet we know that during Alzheimer's two abnormal proteins are made by mutated genes of the brain cells.
Microscopic exam and bacterial culture: As with a standard medical stool culture, a slide is made to check for the balance of bacteria and yeast and abnormal bacterial composition, as well as for white cells and red cells.
This disease makes the body form abnormal lymphocytes, which are a type of white blood cell.
For instance, bigger canines apparently suffer from cancer more often, which could make sense; large dogs grow more than smaller breeds do, and cancer is rooted in abnormal cell growth.
Some cancers manifest themselves in the form of a mass of abnormal cells called a tumor, while others affect cells in the blood or lymph systemA network of organs, lymph nodes, lymph ducts, and lymph vessels that make and move lymph from tissues to the bloodstream.
Abnormal cells in the sample made him suspect cancer.
In cases where a brain tumor begins growing autonomously in the brain, mutations, in the DNA of brain cells cause the cells to grow and divide, forming a mass that is made up of abnormal cells.
A brain tumor is a growth in the brain made of abnormal cells.
This makes it easier to see abnormal cells.
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