Even though it wasn't planned this way, says Atkinson, the three «Tell Your Own Cell Story» videos demonstrate three different approaches to the challenge of
making cell biology visible to the world.
It is a praiseworthy attempt to
make cell biology and the complex science of genetics accessible to young readers.
Not exact matches
«Some
cell types can be more readily
made given today's understanding of developmental
biology and technologies.
By treating
biology as software and reprogramming
cells to treat diseases and other ailments, humans have already
made tremendous progress in medicine, Kurzweil said Sunday.
Cell biology is the same way — the cell itself may be highly organized, and order increased in comparison to the raw materials which make up the cell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increa
Cell biology is the same way — the
cell itself may be highly organized, and order increased in comparison to the raw materials which make up the cell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increa
cell itself may be highly organized, and order increased in comparison to the raw materials which
make up the
cell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increa
cell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increases.
«Simply put, the compound turns - off the sperm's ability to swim, significantly limiting fertilization capabilities,» said lead investigator Michael O'Rand, PhD, retired professor of
cell biology and physiology in the University of North Carolina at Chapel Hill School of Medicine, and president / CEO of Eppin Pharma, Inc. «This
makes EP055 an ideal candidate for non-hormonal male contraception.»
Artificial wombs and embryos
made from skin
cells — remarkable new techniques could revolutionise reproductive
biology and help bring an end to infertility
Researchers at the Walter and Eliza Hall Institute have
made significant contributions to understanding dendritic
cell biology for more than 40 years.
John Glass, a senior microbiologist in the synthetic
biology group at the J. Craig Venter Institute in Rockville, Maryland, puts it this way: If you can imagine a set of genes that will program a
cell to do something — anything — then you can
make them «at a reasonable cost and test your hypothesis... so it will be possible to attempt to design organisms that have extraordinary properties to solve human needs.»
«The production of proteins is a key process in all
cells, and it is important to
make the right amounts of each protein at just the right time,» said Michael Welte, an associate professor of
biology at the University of Rochester.
His lab began by working with Matt Bennett, assistant professor of biochemistry and
cell biology at Rice, to
make use of two tailored forms of E. coli bacteria created by Rice graduate student Chen Ye.
His research career, peppered with landmark discoveries that go all the way from uncovering the basic principles of how DNA instructs
cells to
make proteins to unraveling the genetic blueprint of the puffer fish, is an indelible part of the history of molecular
biology.
In one episode, he interviews a
biology professor who matches the stages of
cell division to memorable theme songs; converting this into a multimedia piece, Shapiro
made a minute - long movie called Pink Floyd and the dancing embryos, splicing together video segments with a musical soundtrack.
«This paper is a great example of how chemistry can help
make step changes in
biology,» says Matthew Dalby, a professor of
cell engineering at the University of Glasgow and co-senior author on the study with Ulijn.
They have
made it easy for anyone with basic molecular
biology training to insert, remove, and edit genes in
cells, including sperm, eggs, and embryos, potentially curing genetic diseases or adding desirable traits.
Several years ago, the lab of UC Berkeley's Nicole King, a professor of molecular and
cell biology and Howard Hughes Medical Institute investigator, discovered that certain bacteria
make these one -
celled choanoflagellates (a.k.a. choanos) develop into multicellular colonies.
At its most basic, synthetic
biology is about
making DNA from scratch, on scales from individual molecules to
cells, tissues and even entire organisms.
In fact, there's reason to believe that all of the properties of
cell biology that
made complex life possible in the next geologic era were put in place here: cytoskeletons that allow eukaryotic
cells to change shape, and
cell polarity that allows
cells to send a molecular message to one side of the
cell but not the other, and to interact with nearby
cells.
Rather than despairing that combinatorial interactions of diets, nuclear genes, and mitochondrial genes
make the underlying
biology of aging intractably complex, Rand and lead author Chen - Tseh Zhu said studies that explicitly embrace such multifactorial interactions can lead researchers to understand the inherent biological complexity of the aging process: Many genes, many
cells, and many environments all contribute to the aging process.
Lundblad, 64, is a
cell biologist who
made her name in telomere
biology and has been at the institute since 2003.
His research group focuses on big data network
biology, exploring biological systems by developing and deploying algorithms aimed to predict
cell behavior, in particular looking at cellular signal processing and decision
making.
«The exciting part of this work is not just that we
made hydrogels, but that we're now equipped with this powerful technique that lets us ask fundamental — and very challenging — questions about them,» says Takanari Inoue, Ph.D., an associate professor of
cell biology at the Johns Hopkins University School of Medicine and senior author of the report on the research published online Nov. 6 in the journal Nature Materials.
Led by researchers at Duke University, the study offers clues to a longstanding question in developmental
biology, namely how plants and animals
make so many types of
cells from the same set of instructions.
Stretch out all of the genomes in all of your body's trillions of
cells, says Tom Misteli, the head of the
cell biology of genomes group at the National Cancer Institute in Bethesda, Md., and it would
make 50 round trips to the sun.
«
Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human
cells — if you can prevent viral entry of HIV into immune
cells, you have won,» says Dr. Blanchard, who is also associate director of Weill Cornell's chemical
biology program.
«We
make a science - based risk assessment [of a product], and if it's safe we use it and if it's unsafe, we don't,» Stefan Jansson, a professor of plant
cell and molecular
biology at Umeå University's Plant Science Centre in Sweden, told ScienceInsider when ENVI approved its draft last month.
Arthur Landy, a distinguished professor of molecular and
cell biology and biochemistry at Brown University, recently decided, however, that he had to remind a former premed student of his that «without evolution, modern
biology, including medicine and biotechnology, wouldn't
make sense.»
Whether it's stuffing DNA inside the nucleus or cramming energy - generating machinery into the rod - shape organelles called mitochondria,
biology separates tasks into specialized compartments within
cells to
make it easier to do specific jobs without interference.
«P53 was already known to monitor many things, like DNA damage and having the wrong number of chromosomes, that
make division dangerous for
cells,» says Andrew Holland, Ph.D., an assistant professor of molecular
biology and genetics at the Johns Hopkins University School of Medicine.
«While genetic modification of crops can introduce new beneficial traits into existing crops, the resulting products need to be tested for long - term health effects before
making assumptions about their impact on human health,» said senior investigator Frances Sladek, a professor of
cell biology and neuroscience at UC Riverside.
Cellular Decision
Making and Interactions, including stem
cell biology, host - microbiome interactions, differentiation and disease, evolution, and immunology.
Focused both on discovery and on mentoring future generations of researchers, Salk scientists
make groundbreaking contributions to our understanding of cancer, aging, Alzheimer's, diabetes and infectious diseases by studying neuroscience, genetics,
cell and plant
biology and related disciplines.
Competing groups are working closer to
biology;
making cells from fatty acids, for example.
Cronin is also trying to
make living things from
cells made of inorganic chemicals (so, chemicals without the atoms, hydrogen, and carbon) in order to show that
biology isn't the only way life evolved on Earth.
«In a young, healthy individual, hypoxia — low oxygen levels — triggers the body to
make factors that help coordinate the growth of new blood vessels but this process doesn't work as well as we age,» says Gregg Semenza, M.D., Ph.D., professor of pediatrics and genetic medicine and director of the vascular
biology program at the Johns Hopkins Institute for
Cell Engineering.
Rockefeller, located on the east side of Manhattan, is where many of the most important advances in molecular
biology and cancer
biology were
made, from Peyton Rous's discovery in 1911 of viruses that cause cancer, to Oswald Avery, Colin MacCleod, and Maclyn McCarty's discovery in 1944 that DNA is the hereditary material, to Ralph Steinman's discovery of dendritic
cells in the 1970s.
But it's one that bioethicists have warned about for at least a dozen years, since advances in stem
cell biology made it easier to produce chimeras.
The field of stem
cell biology has
made major and continuing progress over the last few years towards achieving its much heralded aim of impacting human health.
mRNA is a fundamental component of human
biology, giving
cells the instructions they need to
make proteins that carry out every function of the body.
 Much of transplant
biology focuses on one type of immune
cell (T
cells), but Newell found that the
cells that may
make the biggest difference for long - term tolerance are different, B
cells.
Glass and his Venter Institute colleagues are now using synthetic
biology and synthetic genomics approaches developed at the JCVI to create
cells and organelles with redesigned genomes to
make microbes that can produce biofuels, pharmaceuticals, and industrially valuable molecules.
With decades of private sector leadership and business operations experience, as well as an undergraduate degree in business and PhD in
cell and molecular
biology, Henkin has the skills to help
make the NPA more financially secure and effective in serving its members.
«This could
make a real difference in the increasingly difficult process of cataloguing the human genes,» said Janet Rowley, MD, Blum - Reise Distinguished Service Professor in the departments of medicine, molecular genetics &
cell biology, and human genetics at the University of Chicago and director of the study.
«Over the past year, the international scientific community, from physicians to computer scientists, has engaged in an open process to plan how to go about
making this revolutionary atlas,» said Aviv Regev, a core member, chair of faculty, and director of the Klarman
Cell Observatory and
Cell Circuits Program at the Broad Institute of MIT and Harvard; an HHMI Investigator; professor of
biology at Massachusetts Institute of Technology; and co-chair, with Sarah Teichmann of the Wellcome Trust Sanger Institute, of the HCA Organizing Committee.
Our goal is to
make biology quantitative, because a fundamental goal of
biology is to know the absolute number of molecules in a
cell.
«Although we first became aware of prions because they cause several bizarre neurological diseases, the discovery that something so awesomely similar happens in organisms as different as humans and yeast
makes us suspect that there is a fundamental, common biochemical process at work here,» said study director Susan Lindquist, PhD, professor of molecular genetics and
cell biology and an investigator in the Howard Hughes Medical Institute at the University of Chicago.
Human
biology is not only manipulated by mutations; it is also influenced by the trillions of microbial residents — including viruses — that
make up an estimated fifty percent of the
cells in the human body.
Scientists at The Wistar Institute Melanoma Research Center have
made huge strides in understanding the
biology that underlies this disease, from basic genetics to the study of melanoma
cell interaction with the microenvironment and new concepts that describe the stem
cell - like abilities of melanoma to evade treatment.
The Van Oudenaarden group uses a combination of experimental, computational, and theoretical approaches to quantitatively understand decision ‐
making in single
cells, with a focus on questions in developmental and stem
cell biology.
Recent progress in phylogenomics, and the implementation of modern molecular, microscopy, and
cell biology techniques in a handful of spiralian model systems have
made that possible.