Sentences with phrase «making cells in the bone marrow»

Subsequent tests revealed that the retrovirus used to ferry the corrective gene into the DNA of blood - making cells in the bone marrow had lodged in or near a gene that regulates T cells, possibly prompting their uncontrolled growth.

Not exact matches

The cancerous cells win out over the healthy blood cells in the bone marrow, which in turn leads to kidney problems when the cancer cells make abnormal proteins instead of antibodies.

Such embryo research might teach us more about cell differentiation and early embryo development, it might make possible greater success in bone marrow transplants, and it might help us to treat more successfully degenerative diseases and spinal cord injuries.

Jerrold Olefsky and colleagues at the University of California, San Diego, killed the bone marrow cells in mice that make immune cells called macrophages.

Bone marrow transplants are sometimes needed to treat immune diseases that attack these stem cells, or in certain types of anaemia, in which the body can't make enough blood cells or clotting factors.

The scientists suspected that the lost enzyme might affect the animals» mesenchymal stem cells (MSCs)-- stem cells found in the bone marrow that are capable of developing into both the bone cells and fat cells that make up our skeletons.

By studying the receptor for thrombopoietin, called Mpl, on blood cells in the bone marrow, the team pinpointed the cells involved in making platelets after thrombopoietin stimulation, and made an unexpected discovery.

Platelets are made by enormous megakaryocyte cells in bone marrow.

Pre-malignant MPN occurs when the bone marrow makes too many blood cells, and in 10 per cent of patients can lead to overt leukemia.

The study developed a new in vitro system made from bone marrow stem cells and studied what would happen if its ambient temperature fell below 37 °C (the natural temperature of the human body).

In the paper that is now published, they make the stem cells in the bone marrow to produce more telomerase, thus enabling them to repair their excessively shortened telomereIn the paper that is now published, they make the stem cells in the bone marrow to produce more telomerase, thus enabling them to repair their excessively shortened telomerein the bone marrow to produce more telomerase, thus enabling them to repair their excessively shortened telomeres.

«Ferric citrate binds the phosphorus in food and also increases iron in the blood, and it allows patients to need less or no IV iron and medicines to make their bone marrow produce more blood cells,» said Dr. Lewis.

These findings may help explain why some people with mutations in certain ribosomal protein genes develop conditions such as Diamond - Blackfan anemia — a blood disorder in which the bone marrow doesn't make enough red blood cells — but don't have problems in other body tissues, Ware says.

These so - called hematopoietic stem cells (from Greek meaning «to make blood») have been reliably used over the past 40 years to seed bone marrow transplants in the treatment of some cancers and immune disorders.

All immune system cells are made from stem cells in the bone marrow.

As part of a clinical trial conducted at Northwestern University in Chicago, Illinois, Ildstad and colleagues extracted bone marrow - producing cells from kidney donors and then removed cells likely to cause GVHD while expanding the number of «facilitating cells» that make an organ recipient's system more receptive.

In this tissue system, we can culture patient - derived megakaryocytes — the bone marrow cells that make platelets — and also endothelial cells, which are found in bone marrow and promote platelet production, to design patient - specific drug administration regimes.&raquIn this tissue system, we can culture patient - derived megakaryocytes — the bone marrow cells that make platelets — and also endothelial cells, which are found in bone marrow and promote platelet production, to design patient - specific drug administration regimes.&raquin bone marrow and promote platelet production, to design patient - specific drug administration regimes.»

The concept was first tested inadvertently in Germany in 2006, when a person with leukaemia who was also HIV positive received a bone marrow transplant that happened to come from someone whose blood cells couldn't make CCR5 proteins.

Although Osteolectin is known to be made by certain bone marrow and bone cells, CRI researchers are the first to show Osteolectin promotes the formation of new bone from skeletal stem cells in the bone marrow.

The diagnosis of multiple myeloma is made by the presence of elevated abnormal plasma cells in the bone marrow.

(Epogen, Procrit) A man - made version of a naturally occurring substance in the body (erythropoietin) that encourages the bone marrow to make more red blood cells.

(G - CSF, Neupogen) A man - made version of a naturally occurring substance in the body that promotes white blood cell growth in the bone marrow.

In this type of plasma cell neoplasm, less than 10 % of the bone marrow is made up of abnormal plasma cells and there is no cancer.

In that condition, stem cells collected from the blood or bone marrow could be removed from a patient, edited in the lab to correct the DNA typo — a process called «ex vivo» gene editing — and then reinjected to proliferate and make a patient healthIn that condition, stem cells collected from the blood or bone marrow could be removed from a patient, edited in the lab to correct the DNA typo — a process called «ex vivo» gene editing — and then reinjected to proliferate and make a patient healthin the lab to correct the DNA typo — a process called «ex vivo» gene editing — and then reinjected to proliferate and make a patient healthy.

Plasma cells develop from B lymphocytes (B cells), a type of white blood cell that is made in the bone marrow.

The chemotherapy is designed to make space in the bone marrow for the gene - corrected hematopoietic stem cells to settle in and start working.

Myeloproliferative neoplasms (MPNs) are blood disorders in which the bone marrow makes too many of one or more types of blood cells — white blood cells, red blood cells or platelets.

These advances make it possible for half - identical bone marrow transplants to be used in nonmalignant diseases, such as aplastic anemia, lupus, and sickle cell anemia.

It is through this research program that Penn has made significant advances in improving bone marrow and stem cell transplants.

To cure babesia requires treating at least one month longer than the average length of time a red blood cell lives after it is made by the bone marrow in the center of bones.

In other cases, people who have had had high doses of radiation or chemotherapy to destroy life - threatening cancer cells, the treatment can stop their bone marrow's ability to make blood cells.

Gums are pale because the bone marrow, which makes red blood cells (RBCs), does not function well in cats with leukemia.

The signs that we see in dogs are usually related to decreased numbers of normal cells (such as red blood cells which carry oxygen, white blood cells that fight infection and platelets that help with clotting) which are made in the bone marrow.

White blood cells and platelets that are normally made in the bone marrow pick up this virus and bring it back into the circulation.

When the virus infects these areas the lining of the intestine literally dies, the bone marrow can not make red or white blood cells in adequate quantity, and the immune system can become impaired.