Sentences with phrase «making islet cells»

Not exact matches

Diabetes researchers are considering various replacements for insulin injections: Transplanting new pancreatic islet cells that make insulin, coaxing the patient's own islets to regenerate, or treating diabetics early in the disease with immune - suppressing therapies to prevent their body from destroying the rest of their pancreatic islets.

Using the material and protein combination, the researchers evaluated multiple locations for implanting the islet cell clusters, the first time such a direct comparison of transplant sites has been made.

The investigators demonstrated robust new growth of islets and their saliva - making equivalents, and by a painstaking procedure, they proved Faustman's final proposition — that spleen cells had converted to both islets and salivary tissue.?

«The loss of insulin - producing beta cells leads to type 1 diabetes, making it an ideal target for cell replacement therapy,» said James Shapiro, MD, PhD, FRCSC, Director of the Clinical Islet Transplant Program, University of Alberta.

Once implanted, the cells are designed to differentiate into the various cell types that make up the pancreatic islet, which could allow for production of insulin and other hormones, such as glucagon, needed to control blood sugar levels.

The pluripotent stem cell process could allow researchers to make genetic changes to dampen or potentially eliminate the rejection of the pig islets by the human immune system.

Unfortunately, conventional sorting techniques have not been sufficient to isolate the individual islet cell types, making it impossible to analyze each one's gene expression program and its potential contribution to dysfunction.

Neuroendocrine pancreas cells (such as islet cells) make several hormones, including insulin and glucagon, that help control sugar levels in the blood.

Based on animal experimentation, PEC - 01 progenitor cells have the capacity to both self - renew; making more cells, and differentiate into mature, functional pancreatic islet cells.

The immune system attacks and damages the islet cells that make insulin in the pancreas.

Insulin is a hormone made in the beta cells in the islets of Langerhansin the pancreas.

It is critical to monitor insulin needs very closely if an attempt is made to correct high blood sugar using insulin in a dog with acute pancreatitis, in order to avoid the risk of shock due to an over dosage of insulin when the islet cell function returns and the pancreas begins to make insulin normally.