Thus far, innate resistance to
malaria infections in humans has been attributed to blood group polymorphisms.
Not exact matches
A study of the way
malaria parasites behave when they live
in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single
infection in order to hide from the immune system.
For their studies on a species of
human malaria that is also carried by monkeys, as part of a larger project funded by the UK Research Council Living with Environmental Change initiative, Fornace and her colleagues are using a drone to map changes
in mosquito and monkey habitats and correlate how those changes affect
human infection.
«The first generation GAP strain had two genes removed from the
malaria parasite, but this new «triple punch», developed
in collaboration with scientists at the Walter and Eliza Hall Institute
in Australia, removes three separate genes associated with the pathogenicity of the parasite, effectively abrogating its ability to establish an
infection in humans.»
Recent studies have identified genetic variants that account for variability
in human susceptibility and severity of
infection and might be useful for vaccine and treatment development
in malaria [80][84] and dengue [85], [86], for example.
Ethical considerations
in Controlled
Human Malaria Infection studies in low resource settings: Experiences and perceptions of study participants in a malaria Challenge study i
Malaria Infection studies
in low resource settings: Experiences and perceptions of study participants
in a
malaria Challenge study i
malaria Challenge study
in Kenya
The long - tailed macaque carries a virulent strain of
malaria that is responsible for an increasing number of
human infections in Malaysia.