The studies support the concept of using natural exposure in combination with malaria - fighting drugs to help people build up protection against disease, says
malaria vaccine researcher Robert Sauerwein of the Radboud University Nijmegen Medical Center in the Netherlands.
Not exact matches
By examining blood plasma of two - year - olds exposed to the disease,
researchers have discovered a new
vaccine target: a protein recognized by the immune systems of
malaria - resistant children.
In these countries pneumonia,
malaria and diarrhea were the leading causes of death), so to improve survival in these regions the
researchers recommended improving the uptake of breastfeeding, providing
vaccines for pneumonia,
malaria and diarrhea, and improving water and sanitation.
«New
malaria vaccine effective in clinical trial:
Researchers achieve protection of up to 100 percent using fully viable
malaria parasites.»
The
researchers analyzed the bodies» immune reactions and identified protein patterns which will make it possible to further improve
malaria vaccines, Kremsner added.
University of Tübingen
researchers in collaboration with the biotech company Sanaria Inc. have demonstrated in a clinical trial that a new
vaccine for
malaria called Sanaria ® PfSPZ - CVac has been up to 100 percent effective when assessed at 10 weeks after last dose of
vaccine.
When a biotech company called Sanaria presented the results of a clinical study of its unconventional
malaria vaccine last year, many
researchers were disappointed.
A study led by Johns Hopkins Bloomberg School of Public Health
researchers found that injecting a
vaccine - like compound into mice was effective in protecting them from
malaria.
That
vaccine, called RTS, S and produced by GlaxoSmithKline, has provided between 50 % and 60 % protection in previous studies; although it could make a major dent in
malaria deaths,
researchers are hoping for something far better in the long run.
But as
researchers turn to diseases that are more difficult to protect against, such as
malaria or HIV, they are setting their sights lower, aiming for
vaccines that prevent severe disease but not infection.
The
malaria researchers want the president to initiate an «aggressive
malaria vaccine program» and raise federal funding from the current $ 25 million to $ 500 million a year; in addition, the U.S. should commit to buying $ 500 million a year worth of
vaccines once they've been developed, to guarantee the industry a market.
«Many
researchers are trying to find ways to develop a
malaria vaccine by preventing the parasite from entering the red blood cell, and here we found a way to block it from leaving the cell once it has entered.
Only one
vaccine has been licensed, and neither it nor any others in development today will be 100 percent effective against
malaria infection, said lead
researcher José A. Stoute, associate professor of medicine and microbiology and immunology.
While attempts to eradicate the disease often focus on killing mosquitoes — the carrier of the disease — Yale
researchers have recently made strides in finding a
malaria vaccine...
Massachusetts Institute of Technology (MIT)
researchers have discovered a new way to model
malaria using stem cells in a petri dish, which will allow them to test potential antimalarial drugs and
vaccines.
The finding «can color how we approach future
vaccine discovery and development,» said Broad senior associate member Dr. Dyann Wirth, a top
malaria researcher at Harvard who led the study along with Fred Hutch biostatistician Dr. Peter Gilbert.
Progress towards the development of highly effective
vaccines for
malaria has been frustratingly slow, but a distinctive bright spot for
malaria vaccine and immunology
researchers is the availability of human experimental models of P. falciparum - infection and
malaria immunity.
While
researchers are working to find better cures and ways to prevent contracting the diseases and hopefully a
vaccine for
malaria, there is still more work to be done.