We are investigating the cellular and genetic damages that transposons can inflict on
the male germ line, as well as the cooperation of different levels of transposon control, including specialized small interfering RNAs.
The first focuses on the protection of
the male germ line against transposons.
Thus, regional / species specific variation in DNA gain and loss are primarily driven by clade specific / recent transposons interacting with open chromatin either in
the male germ line, female germ line or early embryo.
Not exact matches
But because the vinclozolin - induced fertility changes occurred in almost every
male rat descended from a treated mother rather than in a small percentage of offspring (as is seen in
germ line mutations caused by radiation), Skinner suspects an epigenetic mechanism — a change that doesn't mutate the DNA sequence of an animal, but rather affects how genes are expressed.
To begin passenger pigeon de-extinction we need the successful establishment of both a
male and female primordial
germ cell cell
line.
What ensures that at these DMRs, DNA methylation is established in only tile
male or the female
germ line is unknown.
When a
male germ -
line chimera is mated to a female
germ -
line chimera they will have three types of offspring — pure band - tailed pigeons, band - tail - passenger pigeon hybrids, and when an engineered sperm meets an engineered egg cell the result will be a fully formed de-extinct passenger pigeon.