Drawing upon the cell culture expertise of Noriyoshi Sakai, Ph.D., and Kayoko Kurita, of Fukui Prefectural University, the Japanese - U.S. team developed a system that enables immature sperm cells, or spermatagonia, taken from
male zebrafish to survive long enough in vitro that they can receive foreign genes inserted by a retrovirus.
For example,
male zebrafish with more numerous or more effective breeding ornaments — and thus lower regenerative potential — might contribute more to the gene pool, phasing out regenerative potential over generations.
«We discovered that
male zebrafish have a very important set of structures on their pectoral fins that they use for breeding and that these structures secrete a potent molecular inhibitor of a key signaling pathway to aid their cycles of regular replacement,» explains senior author Kenneth Poss of Duke University Medical Center.
Spiked structures on
male zebrafish pectoral fins are important for mating but also produce a potent signaling inhibitor.
Not exact matches
Studies found that a derivative excreted by juiced cattle reduces minnows» fertility, transforms female
zebrafish into
males, and induces other masculinizing effects.
At Baltimore's Thomas Jefferson Elementary Middle, third - grade students who were given
male and female
zebrafish one day this fall were amazed, just 24 hours later, to see embryos form, and thrilled to observe the growing life forms under a microscope.