Inflammatory breast cancer is a rare and aggressive form of breast cancer that occurs when
malignant cells block the skin and lymph vessels of the...
Not exact matches
The researchers demonstrated that
blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and
malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect on normal
cells or peritoneal pancreatic cancer controls.
When the researchers deliberately
blocked the gene's activity in cultured breast
cells by adding RNA sequences that bound to BRCA1 mRNA, preventing it making protein, they found that the
cells began to divide rapidly, just like
malignant cells.
Researchers at the University of Chicago noted that in recent years, genetically engineered herpes simplex virus studied for its efficacy against
malignant tumors of the central nervous system and the liver was
blocking certain types of
cell death and proliferation of surviving
cells.
They report that the use of PD - 1 / PD - L1 monoclonal
blocking antibody allows T
cells to remain active and fight
malignant evolution.
Malignant cells also depend on another fuel, glutamine, an amino acid that
cells can metabolize to produce both energy and building
blocks.
Researchers report that PD - 1 / PD - L1 monoclonal
blocking antibody allows T
cells to remain active and fight
malignant evolution, subsequently preventing tumor resistance.
The lab further developed inhibitors to target the expression of XBP - 1 and established that
blocking the expression of XBP - 1 by specific small - molecule chemical inhibitors can stall
malignant progression of leukemia in mice and induce apoptosis in primary human leukemic
cells.
In a paper published online Aug. 31, by Nature Medicine, researchers report that using a monoclonal antibody called anti-CD47, which
blocks the «don't - eat - me» signal on
malignant cells, to treat mice with an intact immune system provides a much more lifelike way to study and develop an immune - based cancer therapy.
Blocking Hemangiosarcoma Tumor Growth Hemangiosarcoma, a
malignant cancer of blood vessel
cells, is an aggressive disease that is rapidly fatal in dogs.