J. Marc Simard, professor of neurosurgery at the University of Maryland School of Medicine, along with colleagues at Yale University and Massachusetts General Hospital, found that Cirara, an investigational drug, powerfully reduced brain swelling and death in patients who had suffered a type of large stroke called
malignant infarction, which normally carries a high mortality rate.
Patients received E-CPR for a number of reasons, such as acute myocardial
infarction,
malignant arrhythmia, myocarditis, acute pulmonary embolism, and hypothermia.