Sentences with phrase «mammalian gene function»

Steve Brown, MRC Harwell - Relevance of an encyclopedia of mammalian gene function for precision medicine initiatives

One of the most important tools at our scientific disposal in understanding mammalian gene function is the laboratory mouse.

Not exact matches

«New innovative method for delivering genes into cells: Modification of cell physiological function with novel parallelized electroporation of mammalian cells by using electrostatic manipulation in a water - in - oil droplet.»

First, they managed to make the bacterial lysostaphin gene function effectively in cultures of mammalian cells.

They show that CHRONO functions as a transcriptional repressor of the negative feedback loop in the mammalian clock: the protein CHRONO binds to the regulatory region of clock genes, with its repressor function oscillating in a circadian manner.

Dillin notes that this work is already being done, adding that pha - 4 has three mammalian homologues (similar genes serving similar functions) falling under the Foxa family of genes, which regulates the pancreatic hormone glucagon in the pancreas and liver.

Studying embryos of the little skate, Gillis focused on the gene Sonic hedgehog, which produces a signaling protein whose function is well understood in the mammalian limb.

Elucidating functions of commensal microbial genes in the mammalian gut is challenging because many commensals are recalcitrant to laboratory cultivation and genetic manipulation.

In the long term, the project aims to enable the research community to establish the traits associated with the function of every protein - coding gene in the mammalian genome.

The discovery of short hairpin RNAs (shRNAs) suppressing gene expression in mammalian cells enables large - scale loss - of - function screens by using genome - wide shRNA libraries.

Mammalian Y chromosome genes with important functions are transferred to autosomal chromosomes more often than previously thought, a study shows.

Improve the knowledge of the mammalian genome by deciphering the function of genes in integrated processes.

In Axel's lab, Littman embraced a then - novel technique for transferring genes into mammalian cells to parse their functions.

PHENOMIN's scientists have collaborated with 17 different centers over the world to identify and decipher the function of genes that are essential for mammalian life.