«A way to stabilize haploidy in animal cells:
Mammalian haploid cells present problems during mitosis that limit their viability; the removal of the p53 tumor suppressor gene increases the survival rate of these cells thereby stabilising their haploid state.»
The emergence, in recent years, of the first
mammalian haploid cell lines has raised great expectations in the scientific community.
Not exact matches
Here, we demonstrate the feasibility of classical genetic screening in
mammalian systems by using
haploid cells, chemical mutagenesis and next - generation sequencing, providing a new tool to explore
mammalian genetic interactions.