Cambridge, Mass. — June 16, 2014 — A team of researchers led by David J. Mooney, Robert P. Pinkas Family Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences (SEAS), have identified a possible mechanism by which normal cells turn malignant in
mammary epithelial tissues, the tissues frequently involved in breast cancer.
By manipulating it in vitro, a team of researchers led by Prof. David Mooney at Harvard SEAS have identified a possible mechanism by which normal cells turn malignant in
mammary epithelial tissues, the tissues frequently involved in breast cancer.
Not exact matches
They removed
epithelial cells from the fourth
mammary gland of each mouse, leaving behind the stromal
tissue.
Using cutting - edge techniques enabled by next - generation sequencing, the authors generated complete methylome maps at single nucleotide resolution in a low - passage breast cancer cell line and normal breast
tissue (primary human
mammary epithelial cells).
(C) Degree of branching and number of
mammary epithelial cell layers in the
mammary tissue formed by
mammary cells infected with miR - 150.
In normal
mammary tissues, LARP7 was highly expressed in the
epithelial cells of the
mammary lobuli and terminal ducts (Figure 1C).
They arise from different types of
tissues (
epithelial or glandular
tissues, and mesenchymal or connective
tissues) in the
mammary gland.
Mammary gland tumors can be either malignant (cancerous) or benign (non-cancerous) and arise from the different types of tissues (epithelial or glandular tissues, and mesenchymal or connective tissues) in the mammary
Mammary gland tumors can be either malignant (cancerous) or benign (non-cancerous) and arise from the different types of
tissues (
epithelial or glandular
tissues, and mesenchymal or connective
tissues) in the
mammarymammary gland.