Sentences with phrase «mammary epithelium»

Decreased IGF type 1 receptor signaling in mammary epithelium during pregnancy leads to reduced proliferation, alveolar differentiation, and expression of insulin receptor substrate (IRS)-1 and IRS - 2.

Selective response to insulin versus insulin - like growth factor - I and - II and up - regulation of insulin receptor splice variant B in the differentiated mouse mammary epithelium.

When this model was in its softest mode, normal (benign) mammary epithelial cells behaved normally within it, forming cellular structures referred to as acini that capture many key features of the normal in vivo mammary epithelium.

Among the experimental MMTV - tva virgin mice that were euthanized at 8.5 weeks post RCAS - caErbb2 infection (described in Figure 1C — E), a small subset (20 %) exhibited high baseline levels of pSTAT5 in both the normal mammary epithelium and early lesions, while the rest had barely detectable pSTAT5 in either (Figure 4 — figure supplement 2A).

In this study, we show that miR - 142 reduced the protein level of APC and enhanced the canonical WNT signaling pathway in normal and malignant mammary epithelium.

Human milk contains live maternal cells, which include blood - derived leukocytes, cells of the mammary epithelium and cell fragments.

These include blood - derived leukocytes, cells of the mammary epithelium, stem cells and cell fragments, which provide immune - protection to the infant.

These cells, called the mammary epithelium, undergo drastic changes throughout a woman's life, and the majority of breast cancers originate in these tissues.

Fibrous collagen is not normally found in the basement membrane that surrounds the mammary epithelium, so any collagen signaling could confound the conclusions of those studies.

This period is characterized by rapid ductal growth and active proliferative activity of the mammary epithelium of Lob 1.