Sentences with phrase «mammary tumors in mice»

Linoleic acid, an omega - 6 fatty acid, has been shown to encourage the growth of mammary tumors in mice.

The researchers studied mammary tumors in mice caused by the over production of a protein called Wnt1, which is secreted by tumor cells and is needed to advance tumor growth.

Not exact matches

The researchers confirmed these findings in a mammary carcinoma mouse model — treatment with dasatinib just a few days after administering two high doses of chemotherapy prevented tumor growth and increased survival rates.

In one experiment, 26 of 50 well - fed mice developed mammary tumors after two years, compared with zero of 50 that were allowed only enough food to keep them going.

Loss of the RING domain predicted poor treatment responses in both mouse and human mammary tumors.

«For example, mouse mammary tumors shared a signaling pathway that is found in human lung cancer and controls how cells reproduce and move from one location to another.»

The absence of tumors in virgin Nrk mutant mice strongly suggests that the tumorigenesis is closely related to the proliferation of mammary epithelial cells during pregnancy.

«The current study investigated the impact of dietary sugar on mammary gland tumor development in multiple mouse models, along with mechanisms that may be involved,» said co-author Lorenzo Cohen, Ph.D., professor of Palliative, Rehabilitation, and Integrative Medicine.

The Rac inhibitor EHop - 016 inhibits mammary tumor growth and metastasis in a nude mouse model.

The Rac inhibitor EHop - 016 Inhibits Mammary Tumor Growth And Metastasis In A Nude Mouse Model Translational Oncology PMID: 25389450 [PubMed] PMCID: PMC4225654.

The expression of a tumor - suppressing protein called TGF beta is more pronounced in the mammary gland of mice that are resistant to cancer (right column) than in the mammary gland of mice that are susceptible to cancer (left column).

Moreover, ablation of a STAT5A allele reduces tumor incidence in a mouse model of breast cancer in which mammary epithelial cells express T antigen (48).

These mice developed multiple independent mammary tumors of which the majority resembled human ILC in terms of morphology and gene expression.

Last year, Mandriota and collaborators demonstrated that in a cancer mouse model, concentrations of aluminum in the amount of those measured in the human breast are able to transform cultured mammary epithelial cells, allowing them to form tumors and to metastasize.

Wang et al. tested a large collection of kinases and found that one called MELK caused tumors to grow in the mammary glands of mice.

Spontaneous mammary tumor development in C3H / HeJ mice was reduced.

«The current study investigated the impact of dietary sugar on mammary gland tumor development in multiple mouse models, along with mechanisms that may be involved,» said co-author Lorenzo Cohen, Ph.D., professor of Palliative, Rehabilitation, and Integrative Medicine.

Etiology: The cause of mammary tumors is unknown in any species except mice, in which an oncornavirus is causative in certain inbred strains.

Mammary (breast) tumors are probably the most common type of cancer seen especially in rats and mice.

Human Warnings: Carcinogenesis: Nitrofurazone has been shown to produce mammary tumors in rats and ovarian tumors in mice.