Sentences with phrase «manipulate host responses»
«Paradoxically, the study does offer some good news for those working on live vaccines or live vaccine vectors because these are not just vaccine antigens but organisms in their own right that necessarily manipulate host responses (such as those involving IL28B) for their own survival.
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In addition, the strain isolated from lions and hyenas during the 1993/1994 epidemic had rare mutations in two viral proteins: the CDV - H protein, which binds to the host cell receptor (called SLAM CD 150) and therefore plays an important role to facilitate viral entry into host cells, and the CDV - V protein, which enables the virus to manipulate the innate immune response of the host.
Malcolm's main research interest lies in determining and examining the host / pathogen interactions that initiate and control immune responses, how these interactions can be beneficially manipulated, and, ultimately, their practical application within disease control programs.
These results suggest that C. rodentium manipulates host metabolism to evade innate immune responses and establish a favorable gut ecosystem.