Sentences with phrase «many aggressive cancers»

April learned about her aggressive cancer just 11 days after giving birth to her fourth child.

How long until the aggressive cancer that ran rampant through my pregnant body, and only my pregnant body, dug in its heels and took me down?

Pre-pubertal girls can't yet biologically produce mature oocytes, and some sexually mature women, such as Bott, have aggressive cancers that must be treated immediately.

To their surprise, they found that these Th17 - deficient mice experienced far more aggressive cancer growth than normal mice — with the cancer completely smothering the lungs within 16 days.

Sonali Setua, a PhD student who worked on the project, said: «It was hugely satisfying to chase such a challenging goal and to be able to target and destroy these aggressive cancer cells.

Due to an inability to differentiate aggressive cancers from nonaggressive types, physicians treat the majority of cases, which may lead to side effects such as impotence and / or incontinence.

Researchers at A * STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers.

«This is not a cure, but it does demonstrate what nanotechnology can achieve in fighting these aggressive cancers.

The hardy cells that survive anticancer drugs and radiation often produce aggressive cancers.

«We discovered that the aggressive cancer cells that are spreading in colon, breast, and skin cancer contained a much higher portion of the protein PITPNC1, than the non-aggressive cancer cells,» says researcher Nils Halberg of the CELLNET Group at the Department of Biomedicine at UiB.

This is likely another reason aggressive cancer rates are rising among young adults.

«Study identifies potential treatment target for pancreatic cancer: Molecular signature found in 30 percent of PDAC tumors associated with more aggressive cancer.»

In testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemotherapy treatment.

The researchers found that patients diagnosed with the most aggressive cancers had higher prevalence and severity of obstructive sleep apnea.

The most common type of non-Hodgkin lymphoma in adults, DLBCL is an aggressive cancer that can develop in many types of tissue.

Of the 113 volunteers enrolled in the study, 41 men — or 36 percent — were found to have more aggressive cancer than initially suspected, meaning they were not good candidates for active surveillance.

UCLA researchers found that conventional «blind» biopsy failed to reveal the true extent of presumed low - risk prostate cancers, and that when targeted biopsy was used, more than a third of these men had more aggressive cancers than they thought.

«The goal is to find specific biomarkers of aggressive cancers,» said Charles Brendler, MD, Co-Director of the John and Carol Walter Center for Urological Health & Program for Personalized Cancer Care at NorthShore and author of the study.

Silverman, too, suspected an RNA virus might be the infectious cause of aggressive cancers in relatively young men.

«Aggressive cancers contain regions where the cancer cells are starved for oxygen and die off, yet patients with these tumors generally have the worst outcome.

«This remodeling process of the cell proteome by autophagy is an important immune - suppressive survival mechanism for Ras - driven cancers, and inhibiting autophagy can provide a means to target these aggressive cancers,» notes White, who is also a distinguished professor of molecular biology and biochemistry at Rutgers School of Arts and Sciences.

Nagrath said, «The higher STAT3 is, the more aggressive the cancer.

This correlation made sense for such an aggressive cancer.

Pancreatic cancer is among the most aggressive cancers known today.

It is the unfortunate few who will develop an aggressive cancer.

The researchers found that the more aggressive the cancer, the higher the expression of this protein, which helps maintain cellular stability.

Prostate cancer is has a genetic component but it has until now been impossible to understand how aggressive the cancer might be Now a new multi-national study has discovered the basis of a simple blood test which can predict whether a man is susceptible to aggressive prostate cancer.

Specifically, they found that mutations of KRAS and IDHs, which are linked to more aggressive cancers, were less common in the cancers in patients with chronic hepatitis.

MYC's role in cancer was discovered more than 30 years ago in the laboratory of UCSF Nobel laureate and Chancellor Emeritus J. Michael Bishop, MD, and it has since been implicated in many aggressive cancers.

The targets of these drugs were not know to be present in cancer cells and therefore no one had considered the possibility that these drugs might be effective against aggressive cancer types, says Professor Ivaska.

«We believe that this novel platform is also important to explore to control more aggressive cancers.»

«It's incredibly encouraging to find possible new options for patients with an aggressive cancer like triple negative breast cancer, and that studies conducted by separate teams at leading institutions agree on the implications of the findings,» said Alan Ashworth, PhD, FRS, president of UCSF Helen Diller Family Comprehensive Cancer Center, and former CEO of the ICR.

The genomic particularities of HeLa cells relate to their origin from an aggressive cancer and subsequent cultivation in laboratories for decades, both of which cause considerable genomic alterations.

The Decision Counseling Program © developed by Dr. Myers and colleagues differs from previous decision aids in that a nurse educator uses the program not only to provide information about options, but also to identify and weigh the importance of things that matter to the patient (e.g., worry about treatment side effects, concern about developing aggressive cancer).

Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.

New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers.

The fused gene in turn produces abnormal proteins that destabilize entire chromosomes, resulting in aggressive cancers.

Yet some men with borderline Gleason scores undergo surgery and are found to have aggressive cancers.

Concerned that the drug by itself might not keep his aggressive cancer at bay, Wartman opted for a second transplant — this time with stem cells isolated from peripheral blood from an unrelated donor.

While the disease can be treated successfully in its early stages, Dr. Nghiem says, it is a highly aggressive cancer that is likely to grow quickly and metastasize.

«This could lead to a more aggressive cancer and worse outcomes for cancer patients ─ poorer survival rates.»

The results suggest that the pockets of stiffer extracellular matrix in the breasts of obese women contribute to tumor growth as well as to more aggressive cancers, Fischbach says: «People always think it's all about soluble factors, chemicals.

When researchers looked at subtypes of pancreatic cancer, they found the lowest levels of PDX1 were actually in the most aggressive cancers.

More precise dosing methods and cellular engineering techniques show promise in the effort to improve treatment of aggressive cancers with personalized cellular therapies, according to new studies from researchers in the Perelman School of Medicine and the Abramson Cancer Center at the University of Pennsylvania and The Children's Hospital of Philadelphia.

Combined treatment with two cancer immunotherapy drugs — one a novel immune modulator and one that focuses and activates the antitumor immune response — significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

Glioblastoma, is an aggressive cancer in which tumors grow rapidly and spread rapidly to new sites.

Patients with glioblastoma have very few treatment options, and we need to continue our search for new ways to attack this very aggressive cancer.»

The study's findings, published in the journal Cancer Research, are the first to use these combined agents as an immune stimulator and may have the potential to kill cancerous cells in solid tumors, including some of the most aggressive cancers that form in the lung and pancreas.

The notoriously aggressive cancer has received a lot of publicity in recent years with the deaths of Patrick Swayze and Steve Jobs, both of whom suffered from the disease.

AML is an aggressive cancer.