Sentences with phrase «many cell processes»

Instead, it will conduct a Phase 1b / 2a study that will use «an improved cell processing technique to hopefully improve efficacy,» Fein noted.

As such, it is uncertain that use of an enhanced cell processing method will yield different results.

Along with the study's co-first authors, Drs. Aayoung Hong and Gatien Moriceau, Lo hypothesized that if they could identify the key tumor cell processes triggered by withdrawal of MAPK inhibitors, then scientists can exploit these process with existing or investigational drugs to trigger the maximal levels of tumor cell death immediately following cessation of the initial therapy.

«If we win, the entire regulatory structure for autologous cell processing, with or without culture, will be rewritten such that any physician using good practices and treating patients responsibly can use stem cells as part of his or her medical practice,» he says.

Much of what is known about nerve cell processing comes from single - cell recordings, Singer says.

We have found that there are many well - preserved cell processes in the two species, for example, in embryonic development.

CdLS is known to result from mutations in subunits or regulators of cohesin, a group of linked proteins necessary for cell division and other cell processes.

Cell processes are also determined by the chemical labeling (or marks) and specific spatial organization of our genomes, which are epigenetic characteristics — that is, nongenetic but nonetheless inheritable traits.

Despite all they have learned in the past century, neuroscientists have made little headway in figuring out exactly how brain cells process information.

The IFNGR receptor is one of these membrane proteins and undertakes to activate genes involved in a huge variety of cell processes, including defence against pathogens and cancer.

Unlike genetic mutations that affect DNA and the genome, epigenetic markers turn genes on and off to regulate cell processes, which if altered may lead to disease, he explains.

By examining cell processes both in mice and in human cells, the researchers found out why: Re-esterification helps protect a key cell organelle called the endoplasmic reticulum (ER).

«We know that the pathway is important for normal cells to carry their activities as it is involved in regulating metabolism, that is, how cells process nutrients to obtain energy and how cells use energy to grow.

In both humans and birds, cells process this gene in a way that produces both a full - length protein and a shorter version of the protein.

In collaboration with the team of Eduard Sabidó at the Proteomics Unit of the Centre for Genomic Regulation and Universitat Pompeu Fabra, the researchers analyzed the proteins in Capsaspora to determine how the organism might be regulating its internal cell processes at different life stages.

When this happens, cell processes go out of control.

NPC is caused by a mutation in one of two genes, resulting in problems in how a person's cells process cholesterol in structures called lysosomes.

«New insight on a familiar glow: Green fluorescent proteins for monitoring cell processes.»

Cancer tumours manipulate a natural cell process to promote their survival suggesting that controlling this mechanism could stop progress of the disease, according to new research led by the University of Oxford.

«Cancer hijacks natural cell process to survive.»

The findings may help scientists to better understand the earliest epigenetic changes which can initiate abnormal cell processes, and the transition between the pre-disease state and cancer.

Following cell processing, the ADRCs were injected directly into the patient's heart muscle.

Researchers try to prevent onset of the disease by correcting a brain cell process that goes awry

Each patient then received a kidney from a genetically mismatched relative or unrelated donor; the concoction of donor cells processed by Ildstad's team was given a day later.

Horizontal cells process visual information by integrating and regulating input from rod and cone photoreceptors, which allow eyes to adjust to see well in both bright and dim light conditions.

These toxins manipulate host cell processes to create optimal growth conditions for the bacteria in hiding.

In addition to mature biochemical and cell biological techniques, we've developed and invented a number of advanced laser - based optical techniques to study live - cell processes.

After editing occurs, the Cas9 - sgRNA RNP complex is degraded over time by endogenous cell processes, leaving no remaining footprint that would be capable of producing off - target effects.

In undifferentiated state, they appear fibroblastoid and have small cell body with few long and thin cell processes.

This track will focus on aspects of cell processing relevant to manufacturing of cell - based products.

These are just two examples of the wide - ranging implications of virology research — with revelations about one virus often applying to several others, as well as to normal cell processes.

The cell processing track aims at reproducible, safe and sustainable methods applicable in manufacturing settings for cell - based products intended for cellular therapy.

A revolutionary cell processing technology enabling superior staining and retention of suspension cells for flow cytometry using centrifuge-less washing

Specific approaches taken to overcome these challenges including optimizing cell processing steps such as isolation, washing, expansion, enrichment, labelling and purification.

As the instructions for all cell processes, the DNA must be accessible to the cell's transcription machinery yet be compressed tightly enough to fit inside the nucleus.

An [Na + + K +] coupled L - glutamate transporter purified from rat brain is located in glial cell processes

Cell processing devices, cultureware, bioreactors, GMP - grade reagents, cell separation techniques.

Nucleic acids are not only key molecules for the storage, replication and transcription of genetic information, but also serve as enzymes or regulators of a number of cell processes.

Danbolt NC, Storm - Mathisen J, Kanner BI (1992) An [Na + + K +] coupled L - glutamate transporter purified from rat brain is located in glial cell processes Neuroscience, 51 (2), 295 - 310 PubMed 1465194

Clinical Cell Processing News is a series about new protocols, products and techniques for clinical - grade cell processing and manufacturing.

Stathmin is essential for the regulation of the cell cytoskeleton, which is required for numerous cell processes including regulating the cell cycle, cytoplasmic organization, cell division and cell motility...

This cell processing system is used to produce a cell solution which can engraft to the damaged tissue or bone, further aiding the healing process.

At Okyanos, Adipose - Derived Stem and Regenerative Cells (ADRCs) are isolated and prepared for intravenous delivery utilizing a closed / sterile, fully automated CGMP cell processing system.

For patients receiving direct injections, a closed / sterile, manually operated cell processing technology will also be used to obtain a micro-fragmented, cell - rich product for injection.

The pattern of RGC loss in patients as well as information obtained from laboratory research all point to the fact that an important site of pathology occurs at the optic nerve head, a region where the axonal cell processes of RGCs exit the eye on their way to the visual centers of the brain.

The pluripotent stem cell process could allow researchers to make genetic changes to dampen or potentially eliminate the rejection of the pig islets by the human immune system.

What could medicine look like someday if, instead of focusing primarily on the organ affected by a disease — neurologists examining brain diseases, pulmonologists focusing on lung diseases — our system was centered on how cells process energy?

BSRI has state - of - the - art equipment to support research related to blood and blood product safety in the areas of molecular biology, immunology, virology, tissue culture, cell processing and epidemiology

Once the fat harvesting procedure is completed (Step 1), you will rest in a private patient suite where family members are permitted to join while the cell processing (Step 2) is completed.

The systems biology approach is characterised by a cycle of theory, computational modelling and experiment to quantitatively describe cells or cell processes.