Sentences with phrase «many cellular behaviors»

The cell influences its microenvironment and, at the same time, the microenvironment influences cellular behavior — I am exploring this interrelationship.

«Despite their importance, cellular behaviors that are largely responsible for cancer mortality are poorly understood,» Dr. Terada said.

As a result, scaffold proteins have been exploited by evolution, pathogens, and cellular engineers to reshape cellular behavior.

The living organism is often too complex to identify the specific causes of a particular cellular behavior.

«Our findings fit with the growing appreciation of the importance of a cell's structural and biochemical surroundings in influencing cellular behavior.

However, due to technological limitations, previous genetic studies largely focused on mixed populations of cells, obscuring critical nuances in cellular behavior.

Their observation provides a better understanding of cytoskeletal self - organization in general, which may in turn lead to better drug design and new materials that can mimic cellular behaviors.

Systems biology provides better methods of drug discovery: research teams can measure changes in genetic activity, protein levels and cellular behavior of the immune system in response to a potential vaccine.

UB researchers have pinpointed important changes in cellular behavior that occur in Pemphigus Vulgaris, the rare, blistering skin disease shown in this microscopic image.

Due to these crucial roles in regulating normal cellular behavior, redox status has been recognized as a key area of biological research in various diseases, including cancer.

Importantly, Zika virus also follows the same pattern of cellular behavior of repressing the cell's translation and stress response while promoting its own protein translation.

He also envisions that this kind of nanomechanical phenotyping should allow for the development of predictive models for cellular behavior for any kind of cell.

Proteins perform virtually every task within cells, and accordingly the composition of the ensemble of proteins present at a given time generally determines cellular behavior.

Previous work by Fredberg and colleagues had documented the importance of collective cellular behavior in asthma, showing that cells comprising epithelial tissues — which line the surfaces of all organs throughout the body — can unjam and flow like a fluid, or jam and freeze like a solid.

The goal is to not only provide broadly applicable experimental tools but also help transform the way in which we think about single cells, cell - cell interactions, diseased cellular states and therapeutics so as to create a new paradigm for understanding and designing systems - level cellular behaviors in multicellular organisms.

Neglecting to trim away introns is sometimes associated with abnormal cellular behavior and disease.

They can also spur chronic inflammation and other bad cellular behavior by interacting with the receptor for AGEs, RAGE.

The question of how cellular behavior is controlled is at the center of stem cell biology, and understanding the mechanisms of cell fate regulation is key for treating diseases that occur upon dysregulation, such as cancer or diabetes.

«Noise can be both an obstacle for some types of cellular behaviors as well as a useful feature for others,» Elowitz said.

«Now I see noise as a lens through which to look at all kinds of cellular behaviors.»

Further, there is evidence to suggest that AGEs produce raised levels of chronic inflammation by altering cellular behavior through the receptor for AGEs, RAGE.

ATF2 is a protein that can regulate a vast array of gene expression and therefore can contribute to many cellular behaviors and processes.

By comparing the regulatory networks of pathologic conditions, I expect to gain new insights into the central question: how do regulatory networks instruct cellular behavior under diseased condition and can we discover drugs that can alter these regulatory networks.

The concentrated antioxidants found in this amazing red fruit can actually promote and support proper cellular behavior when abnormal cells begin to wreak havoc in the body, especially for men.

Not exact matches

The model has allowed scientists to get a much closer look into the cellular interactions and biological behavior of M. genitalium, a very simple bacterium that is sexually transmitted between primates and can cause itching, burning or discharge.

I needed to get into the nitty - gritty details of what drives behavior on a cellular or even molecular level.

The group tries to model biological behavior at the tissue, cellular and cell signaling levels.

Using what is called «calcium reporters,» researchers were able to see the neurons firing up inside the worm and record the changes in cellular activity during the egg - laying behavior.

So in 1974, he headed south to Tulane University in New Orleans, Louisiana, for graduate training in physiological psychology: the study of how the brain influences behavior at the neurochemical and cellular levels.

And once I got into brain biology, it became clear you needed to study the brain on the cellular level, and once you began to understand aspects of behavior in the cellular level, you wanted to understand the molecular level.

The sea slug was the model organism for Kreiner's thesis research, which explored how cellular mechanisms mediate simple behaviors and led to a publication in Science.

At the cellular level, these disorders are associated with heightened activity in the basolateral amygdala (BLA), which is known to play a central role in emotional behavior.

The changes in cellular structure and behavior were the opposite of what Xu - Friedman team's saw in a previous study that placed mice in a consistently noisy environment.

These interactions not only enable cell survival, but also influence fundamental cellular properties and behaviors.

White is interested in human behavior, but said humans are difficult to study at the cellular and synaptic level.

«In this way, modern supercomputers allow millions of small timesteps of atomic motions to be simulated, getting us to examine the protein but also cellular membrane behavior on the microsecond timescale.»

Knowledge of the cellular and molecular details of these adaptations could lead to new treatments for the compulsive behaviors that underlie addiction

His research group focuses on big data network biology, exploring biological systems by developing and deploying algorithms aimed to predict cell behavior, in particular looking at cellular signal processing and decision making.

This finding is an important step towards a better understanding of the cellular and molecular underpinnings of addictive behavior, paving the way for the development of effective therapeutics.

In the past decade, researchers have used mouse models to unravel how cellular changes in the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction - related behavior.

These data indicate that cellular metabolic communication plays a critical role in addiction - related behaviors, which may have implications for new strategies to prevent cocaine addiction.

A multicellular marine animal without organs, Trichoplax's feeding behavior may include cellular coordination, resulting in external food digestion, according to a study published September 2, 2015 in the open - access journal PLOS ONE by Carolyn Smith and colleagues from the National Institute of Health in Bethesda, MD..

«Animal without synapses feeds by external digestion using global, local cellular control: Trichoplax feeding behavior may include cellular coordination, communication.»

A team of researchers led by Charles D. Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has successfully translated a new technology to better study behaviors and cellular function to fruit flies.

«It's cellular makeup, it's child behaviors and child attributes, it's family behaviors within communities and environments within state and national level policies,» says Kristen Harrison, founder of the university's Synergistic Theory and Research on Obesity and Nutrition Group (STRONG) Kids project.

Those data were then combined with information about functional changes in cell behavior to develop a nanomechanical profile, or phenotype, for specific cellular states.

Manipulating biological processes with minimal interference, from the cellular level to the behavior of whole organisms, is a burgeoning scientific effort to better understand how living things work and to develop more effective treatments for a range of medical disorders.

Though much is known about the cellular and molecular components of the clock, the connections that link clock cells to overt behaviors, such as rest / activity behavior, have not been identified.

«What we found at the cellular level correlates with the behaviors we saw in the less - anxious, hyper - active mice, which means having overactive pyramidal neurons with their brakes removed could be contributing to these behaviors,» says Zhu.

Neuroscience can range from studying psychology or behavior to investigating how the nervous system functions at a cellular or molecular level.