Sentences with phrase «many cellular compartments»

A magnified transmission electron microscopy view of the rat nucleus accumbens neurons containing mitochondria in different cellular compartments.

Previous research conducted at Mount Sinai found that the trafficking of protein molecules between the nucleus (the cellular compartment containing the genetic information of the cell) and the cytoplasm is altered in neurodegenerative disease.

Whether in a yeast cell or in a neuron, alpha synuclein directly interfered with the rate of production of proteins in the cell, and the transport of proteins between cellular compartments.

«Cells sequester trash in compartments called autophagosomes» Cells follow a set recipe for recycling: First, the autophagosome is formed around the trash, next autophagosomes are transported and merged with lysosomes — another cellular compartment — and finally, the contents are degraded and either secreted or reused by the cell.

Because the amount of ROS present in cells is tightly regulated by iron - dependent processes in the mitochondria (the cellular compartments in which energy is generated), the researchers had proposed iron import into the mitochondria to be essential for this process.

Significantly, Salama said, the researchers found that CrvA localizes to the periplasm, a cellular compartment between the outer and inner membrane of Gram - negative bacteria such as V. cholerae.

Dr. Steven R. Goodman, Editor - in - Chief of Experimental Biology and Medicine, said «Kolossov et al have utilized a genetically - encoded redox probe that has the ability to determine oxidized / reduced glutathione levels within different cellular compartments of living cells.

Wolfram syndrome is caused by a mutation in the gene encoding a protein called wolframin, which resides in the membrane of the endoplasmic reticulum — another cellular compartment that functions as a manufacturing and packaging system and also acts as a reservoir for calcium ions.

Some of these are coated with later generation of carbon (yellow) and iron (red) giving the false impression of cellular compartments.

Using lab - grown mouse astrocytes with variant forms of NHE9, the researchers found a change in the pH (acidity) inside cellular compartments called endosomes, which in turn altered the ability of cells to take up glutamate.

Many life forms on our planet produce ATP in cellular compartments called mitochondria.

Apoptosis stimulated by the 91 - kDa caspase cleavage MEKK1 fragment requires translocation to soluble cellular compartments.

We investigated the role of Srf in two cellular compartments of mouse skeletal muscle (myofibers and adult muscle stem cells) upon different perturbation of muscle homeostasis (hypertrophy, atrophy, regeneration).

Our moxFPs currently represent one of the most inert solutions for imaging in a variety of cellular compartments including the secretory pathway (Figure 2), the inner membrane space of mitochondria and chloroplasts, the extracellular milieu, and gram negative bacteria periplasm.

Most investigators are surprised to learn that FPs are often poorly suited for cellular compartments other than the cytoplasm.

Divergent lactate dehydrogenase isoenzyme profile in cellular compartments of primate forebrain structures.

Autophagy (more specifically macroautophagy) is the process by which cellular compartments, such as membranes and organelles and also protein aggregates, are recycled back into their building blocks [122].

The process uses a computational model to generate predictions about the dynamics of cell receptors in different cellular compartments.

One important problem is automatically detecting the cellular compartment where a fluorescently tagged protein resides, a task relatively simple for an experienced human, but difficult to automate on a computer.

«Cells sequester trash in compartments called autophagosomes» Cells follow a set recipe for recycling: First, the autophagosome is formed around the trash, next autophagosomes are transported and merged with lysosomes - another cellular compartment — and finally, the contents are degraded and either secreted or reused by the cell.

These abnormalities coexist with mitochondrial structural alteration and mitochondrial DNA overproliferation and / or deletion in all brain cellular compartments.

Not exact matches

and 3 additional pockets: giant front nada compartment wherever you'll be able to different baby items; prime center mesh nada pocket, ideal for storing pacifiers and different little items; middle mesh pocket good for your cellular phone.

Derived from Greek terms meaning «self - eating,» the autophagy system sends protein aggregates and malfunctioning cellular components into acidic compartments called lysosomes, where enzymes chew them up.

This poster aims to delve down an additional layer into the cellular proteome, taking a journey into the subcellular compartments within a single cell to discover what secrets each organellar proteome might hold.

Importantly, these newly identified helper proteins channel the cellular garbage by a «self - eating» pathway (autophagy) to the lysosome, a compartment of cells dedicated for destruction and recycling.

Bits of misfolded proteins processed by specialty organelles may accumulate in the main compartment of the cell, the cytosol, where they can be tagged for disposal by the cellular garbage service.

Thus, size constraints suggest that distinct regions of the axon behave as de facto isolated subcellular compartments, and that neurons have evolved strategies to ensure tight spatial and temporal control of critical cellular functions.

This small set of dynamic protein polymer systems underpins the establishment and remodelling of long range cellular order, cell polarity, shape and division, and plays a critical role in control of the dynamic organisation of the internal membrane - bound compartments that distinguish eukaryotes from their prokaryotic ancestors.

We work across disciplines and use a variety of techniques including microfluidics, standard microscopies (electron, optical, fluorescence, confocal), spectroscopies (fluorescence, UV, CD), scattering techniques (X-ray, light), protein expression and characterization and cell - free gene expression to investigate the utility of coacervate microdroplets as robust reaction compartments and cellular mimics.

It has recently been proposed that the primary role of cellular senescence is in mitotic compartments of fixed size in which spatial considerations dictate that a deleted cell is replaced by a neighboring cell.

The iPS cells are cultured on the opposite side of the membrane in the other channel that represents the glomerulus» urinary compartment, where they are induced to form a layer of mature podocytes that extend long cellular processes through the pores in the membrane and contact the underlying endothelial cells.

Among the Elegante's standard equipment: «Twilight Sentinel,» which turns headlights on and off at the appropriate times; «Dimming Sentinel,» which dims high - beam headlights for approaching traffic, then restores high beams; center console with fold - down armrest and two storage compartments, one of which can accommodate a cellular telephone; electronic climate control; cruise control; power windows, door locks and trunk - lid release; leather - wrapped tilt - and - telescoping steering wheel.