Sentences with phrase «many classes of drugs»

From this theory came a promising class of drugs called checkpoint inhibitors, which effectively release those brakes.

or, more radically, for posting their genetic data to an anonymized, shared research database that might be used to identify those at risk for certain diseases or to identify those who respond better to specific classes of drugs, from beta blockers to cancer medicines.

The news underlines a larger trend of a promising new class of drugs that could fundamentally shift the way hepatitis C is treated.

Earlier this month, the FDA approved two other treatments for multiple myeloma, including another kind of monoclonal antibody drug (the same class of drug that elotuzumab is in).

Still, fentanyl belongs to the larger class of drugs that includes these prescription drugs.

While high price tags are common for rare disease drugs, Emflaza is part of a class of drugs called corticosteroids that are used for DMD in other parts of the world.

Tecentriq belongs to a class of drugs called PD - 1 inhibitors, which help the immune system to fight cancer by blocking a mechanism that tumors use to evade attack.

A pharmacologist by training, I also knew that the bisphosphonates — a class of drugs developed for osteoporosis sufferers — were then being tested on OI patients.

There are many classes of drugs given during anesthesia, and most of them only make you talkative and amnestic.

Interestingly, theophylline and caffeine are both members of the methylxanthine class of drugs.

The article I read (years ago) was about narcotics so this may not apply to other classes of drugs.

Never mind that the agency's own panel of advisers urged that the drug be rejected, citing concerns that it could promote emergence of drug - resistant bacteria and that the drug belongs to an class of drugs needed as a last line of defense against serious human infections.

The new research, published recently as two separate studies in ACS Central Science and the Journal of the American Chemical Society, demonstrates that a new class of drugs called small molecule RNA inhibitors can successfully target and kill specific types of cancer.

«I don't know if I've ever been more excited about a class of drug than I am about [mRNA],» Whitehead says.

«A new class of drug to treat herpes simplex virus infection.»

«In the future, it's possible that a similar class of drug could be tried on humans.

The researchers, however, also found that it may be possible to mitigate these effects with the use of an experimental class of drugs that can block stress.

To bolster the effects of the BRAF inhibitors, recently a new class of drugs was developed to block an enzyme that acts downstream of BRAF / MEK.

Ergotamines, a class of drugs that constrict blood vessels, come from a toxic fungus that attacks rye.

When a class of drugs called triptans became available in the early 1990s, Healy used them, but over time their effectiveness dimmed.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

Various companies are also testing a class of drugs that target both IGF - 1R and the insulin receptor.

In the fall of 2006, the FDA's veterinary advisory committee voted against approving cefquinome, citing concerns that resistance to this vital class of drug could spread from bacteria in beef to hospital superbugs that respond to little else.

«New synthetic amino acid for emerging class of drugs.»

Among medications that lower cholesterol, ezetimibe is not in the widely prescribed class of drugs called statins, which stop the body from manufacturing its own cholesterol.

This strain of Klebsiella pneumoniae is resistant to most antibiotics, including carbapenems, a class of drugs long used to treat this infection.

Statins, a class of drugs that lower cholesterol in the blood, are prescribed to reduce the incidence of cardiovascular events such as heart attacks and strokes.

OCA is the first in a new class of drugs, farnesoid X receptor (FXR) agonists, and the response of the patients to OCA shows that abnormalities in the system it targets may be critical for this condition.

The long term use of proton pump inhibitors (PPIs), a class of drugs commonly used to treat acid reflux, is linked to a more than doubling in the risk of developing stomach cancer, finds research published online in the journal Gut.

With the release and aggressive marketing of the long - acting narcotic OxyContin in 1996, a class of drugs that had largely been reserved for cancer patients was becoming a go - to treatment for conditions such as lower back pain.

A new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

«We have a lot to figure out about how to use this therapy, and we need to treat a few hundred patients in order to get a better sense of how to refine the synergy of these two classes of drugs.

«New class of drugs shows promise in treating chronic diarrhea.»

The rationale for using spironolactone - an inexpensive, generic, medication - stems from the pioneering research of Bertram Pitt, MD, University of Michigan School of Medicine, who showed the benefit of this class of drugs in patients with heart failure and reduced ejection fraction, and who also served as chair of the TOPCAT Steering Committee.

NEW ORLEANS — A long - awaited study on painkillers called nonsteroidal anti-inflammatory drugs, the most widely prescribed class of drugs in the world, has concluded that the three most commonly used carry a similar risk of cardiovascular complications.

The results of the study, funded by the Malaria Eradication Scientific Alliance (MESA), are published in one of the world's leading medical journals The Lancet Infectious Diseases, and show that adding high doses of ivermectin, an endectocide class of drug, to the antimalarial dihydroartemisinin - piperaquine (DP) had a major and prolonged effect on mosquito mortality.

Crockett points out that antidepressants are the most widely prescribed class of drugs in the US and that it is therefore important to investigate their effects on users» social behaviour and moral judgement.

«Popular class of drugs reverse potentially harmful genetic changes from heart disease.»

«There are incredible synergies between the classes of drugs,» he says.

But then a new class of drugs was developed that proved helpful in treating people in the grip of acute psychosis.

Serial entrepreneur Robert Langer of the Massachusetts Institute of Technology (MIT) and Noubar Afeyan, CEO of the venture capital firm Flagship Pioneering, both in Cambridge, saw the makings of a whole new class of drugs — and the idea of Moderna was born.

A wave of encouraging clinical - trial data is raising hopes for a new class of drugs to treat rheumatoid arthritis.

Mental illness has reached crisis proportions, yet we still have no clear links between psychiatric diagnoses and what's going on in the brain — and no effective new classes of drugs.

Three distinct classes of drugs: dopaminergic agonists (such as D - amphetamine), serotonergic agonists (such as LSD), and glutamatergic antagonists (such as PCP) all induce psychotomimetic states in experimental animals that closely resemble schizophrenia symptoms in humans.

Based on these ratings, each class of drugs was deemed effective (Level A), probably effective (Level B), possibly effective (Level C), or judged to have inadequate or conflicting evidence to support or refute the medications» use (Level U).

The determination of each efficacy level was also based on the rigor and quantity of published studies on the drug class: to be in Level A, for example, a class of drugs must have been supported by at least two «Class I» studies — well - designed, double - blind, randomized, placebo - controlled clinical trials.

Lucy Jones, a tenured professor, has pioneered the use of a certain class of drugs to treat AIDS.

At the moment, no other class of drugs is available to replace artemisinin, and none are near the end of the development pipeline.

The study focused on various classes of drugs used to treat pain (analgesics) and insomnia (hypnotics), as well as drugs to treat anxiety and depression.

Preventative treatment of malaria is a useful strategy to protect young children in Africa, but it is unclear which drug and dosing strategy is most effective, especially with the rise of resistance to a class of drug known as antifolates, such as sulfadoxine - pyrimethamine (SP) and trimethoprim - sulfamethoxozole (TS).