Sentences with phrase «many different kinds of cells»
«We were starting to understand a lot about circuits and cells, and we had the tools to look at gene expression in different kinds of cells?
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Transcription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kinds of cells.
Using a mouse model, the team also demonstrated that two processes during neurodevelopment are regulated by the gene: proliferation — the replication of neuronal stem cells that have the potential to become multiple different kinds of cells, including neurons — and migration — the movement of neurons to specific locations in the brain during development.
For example, nobody knows how many different kinds of cells there are in our bodies.
In a paper published online yesterday in Stem Cells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested embryos.
However, different kinds of cells have different epigenetics, so their expression patterns are different.»
He was particularly interested in creating the simplest of solid organs, a phallus, which has just two different kinds of cells to manage.
Stem cells are renowned for their regenerative capacity, able to grow into many different kinds of cells in the body.
We believe there is an undiscovered world of biology that allows different kinds of cells to synthesize protein at different rates and in different ways, and that those differences are important for cellular survival.»
«Bringing together this team, to do this kind of work means we will be better able to understand how stem cells change as they grow and become different kinds of cells.
A key step in disentangling this vast network is to find ways to access each of the thousands of different kinds of cells in the brain.
Even though they are located in similar locations with very similar feeling and texture on physical examination, these masses are made of of very different kinds of cells.
Not exact matches
This feat is possible because cancer cells emit a different kind of metabolic waste than healthy cells.
That means that the stem - cell therapies have to be converted into whatever cell they're meant to be (heart - muscle cells, neurons, and so forth) before going into the body, rather than using different kinds of stem cells to treat the condition.
Since the first human brain organoids were created from stem cells in 2013, scientists have gotten them to form structures like those in the brains of fetuses, to sprout dozens of different kinds of brain cells, and to develop abnormalities like those causing neurological diseases such as Timothy syndrome.
«What this research shows is that they're using the same cell types with the same kinds of connections we see in the neocortex, but with a very different kind of organization.»
Next steps include expanding the use of the technology to different applications, such as solar and fuel cells; and using the battery to power different kinds of electronic devices.
Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.
At Northwestern University, chemist Samuel Stupp and his research team have developed various types of amphiphile molecules (each end is chemically attracted to a different kind of material) that form self - assembling nanofibers, which in turn can prompt the regeneration of bone and brain cells.
Sean Morrison, director of the Center for Stem Cell Biology at the University of Michigan at Ann Arbor, pointed out that pitting different kinds of stem cell research against each other makes little sense from a research perspectCell Biology at the University of Michigan at Ann Arbor, pointed out that pitting different kinds of stem cell research against each other makes little sense from a research perspectcell research against each other makes little sense from a research perspective.
The «kind of murky status quo» that exists now for regulating stem cell clinics «is quite different than there being laws on the books that explicitly say that what the clinics are doing is legal at the state level,» Knoepfler wrote in an email.
«My sense is that there are different groups out there doing this kind of work, but they haven't opened up their labs» to reporters, says stem cell biologist Paul Knoepfler at the
Two kinds of mouse glial brain cells, microglia and astrocytes, making different versions of the APOE protein were grown with brain nerve cells, or neurons, that make disease - causing forms of tau.
«When you look at the varying types of cell morphologies that correspond to different leukemias, you can statistically look at enough cells using this system to be able to classify different kinds of leukemias,» says Yousaf.
But with humans, she is using iPS cells and has been working to develop the correct protocols to induce her stem cells to differentiate into different kinds of lung tissue.
Healthy skin is protected against microbial attack by different kinds of immune cell, including T cells.
Dogs can do that because their noses contain 900 different types of olfactory receptors, chemical detectors in cells that respond to many different kinds of odor molecules in particular ways.
In spite of the size disadvantage and cell overcrowding, the researchers find the juveniles doing many of the sophisticated things their big brothers can do such as deciphering between different kinds of prey like a mosquito versus a fly.
Our bodies are made of more than 10 trillion cells of hundreds of different kinds, each of which plays its unique role in keeping us alive and healthy.
«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.
Put simply, the pattern of microRNA genes turned on in one kind of tumor was entirely different from the pattern in another kind of tumor, and entirely different again from that seen in healthy cells.
The team uncovered different kinds of dependencies that cancer cells exploit, such as underactive or overactive genes.
Then they determine the sequence of as many of those genes as their grant money will allow — typically around a thousand, coming from a thousand bacterial cells — and use that information to estimate how many different kinds of bacteria are present in the sample.
Leukemia starts in the «hematopoietic» stem cells in the bone marrow that give rise to all the different kinds of mature blood cells.
The researchers harvested satellite cells from both healthy and injured muscle tissue of young mice and from healthy tissue of old mice; extracted these cells» DNA with the histone coatings intact; and used tagged antibodies targeting the different kinds of marks to find which spots on those histones were flagged with either «stop» or «go» signals.
Different materials in the cell use their individual identity, which is not appropriate for this kind of calculation.»
In theory, silicon - based solar cells are capable of converting up to 30 percent of sunlight to electricity — although, in reality, the different kinds of loss mechanisms ensure that even under ideal lab conditions it does not exceed 25 %.
Instead, we observed cells of a different kind, that are anti-inflammatory, which we believe could be significant in accelerating healing,» explains Lucas Kumosa.
These are all questions the researchers hope to answer by studying other kinds of life — such as prokaryotes, organisms devoid of cell nuclei, like bacteria — over longer periods of time, and even in different cities.
The researchers first simulated what kinds of materials and structures would work well to make lithium - sulfur cells last longer, computing how molecules in the cathode would interact with different materials.
By studying the brains of adult birds, scientists may discover the cells that give birth to different kinds of neurons and the growth factors that nurture them.
Moreover, all of the donated pancreases displayed active insulin - producing beta cells, with some of the cells scattered individually and others clumped with different kinds of hormone - producing cells in the normal pancreatic structures called islets.
The quickest, most efficient way to micromanage the cells» developmental decisions was to apply a simultaneous combination of factors that both encouraged the differentiation into one lineage while also actively blocking the cells from a different fate — a kind of «yes» and «no» strategy.
«We think that if this property of mixed lineage transcriptional priming is shared amongst different kinds of stem cells, then resolving these mixed - lineage states will invariably involve counteracting repressors.»
Understanding the circuitry that controls these decisions is central to learning how different kinds of stem cells develop.
The research team discovered that two kinds of T cells, CD4 + and CD8 +, segregated into different zones of the spleen before an immune response took place in mice.
Cardiovascular progenitor cells (CPCs) are generated naturally as the heart forms in an embryo and give rise to a selection of different kinds of heart cells.
In their 2015 study, Tomasetti and Vogelstein compared cancer incidence in the United States to the total number of cell divisions to different kinds of tissues in the body.
«It's a whole bunch of different kinds of cancer cells that are all competing at different growth rates.»
However, the efficacy of this kind of cocktail treatment suffers when the drugs require access to different parts of the cell, a bit like fighting a battle by depositing all your archers on the same spot as your infantrymen.