Sentences with phrase «many first line treatments»

«All endpoints of efficacy and tolerability favoured treatment with pembrolizumab, suggesting it should become one standard of care for first line treatment of patients with advanced NSCLC and high PD - L1 expression.

It is the first time a therapy has improved progression - free survival over the current standard first line treatment with platinum - based doublet chemotherapy.»

Pembrolizumab is set to become a new option for first line treatment of patients with advanced lung cancer and high PD - L1 expression, according to the results of the phase III KEYNOTE - 024 trial presented at the ESMO 2016 Congress in Copenhagen and published in the New England Journal of Medicine.

«Standard first line treatment consists of surgical resection followed by radiation and concomitant and adjuvant temozolomide therapy.

«Fortunately, the majority of cases respond very well to the current first line treatment, which is a combination of chemotherapy and immunotherapy.

It is estimated that up to 10,000 Australians with severe depression and who have not responded to first line treatments, such as medication, could benefit from the new treatment.

Subject must have achieved a CR / CRi / CRp (criteria as defined by [Cheson et al, 2003], see Section 5.3) with first line treatment and has hematologic relapse.

Highly active antiretroviral therapy, or HAART, typically combines three antiretroviral drugs (ARVs) as a first line treatment for HIV infection.

It is recommended as the first line treatment of T2D in all cases.

Three prospective studies have also been published which demonstrate efficacy of the ketogenic diet in infantile spasms unresponsive to first line treatments.

First line treatment includes weight loss, increased exercise and diet change to reduce the risk of diabetes.

Approximately 25 % of patients with PCOS may be resistant to the first line treatment and for these women, the addition of glucocorticoids has been shown to increase the number of matured follicles (Esmaeilzadeh et.

Despite the illustrious career as the star player on the PCOS treatment team, the first line treatment doesn't work for everyone.

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This drug is a sulfa class anti-seizure medication that is rapidly becoming a first line treatment choice but might also be used to supplement more traditional therapies.

# 4 Isoniazid... This is a first line treatment for tuberculosis.

Selective serotonin reuptake inhibitors (SSRIs) as first line treatment for depression were more cost effective than tricyclic antidepressants (TCAs) alone, but less cost effective than TCAs as first line treatment with SSRIs for dropouts.

However, more research is required before STPP is adopted as a first line treatment for the disorders covered in their review.

Not exact matches

An important trigger this year will be the outcome of a study where Darzalex is being tested as first - line treatment in combination with Celgene Corp's Revlimid.

That's because the combo treatment would become a go - to, first - line option in patients regardless of whether or not they have the biomarker PD - L1 (Keytruda is far more effective in people who express high levels of the biomarker).

Its first blockbuster business, a line of HIV drugs, is still growing, and it has promising cancer treatments in the pipeline.

More importantly, the shortage may have caused the deaths of 15 people in 2011 when substitute drugs were used instead of first - line treatment medicines that were in short supply, according to one news report.

Acthar is used to patients who don't respond to first - line treatments (steroids) or who can not tolerate them, the company said.

Merck R&D chief Roger Perlmutter said his company believes the Keynote - 024 results «have the potential to change the therapeutic paradigm in first - line treatment of non-small-cell lung cancer.»

For numerous medical conditions, such as obesity, diabetes, insomnia, and chronic pain, the «first - line» and most effective treatments are often behavioral.

Dr. Robert H. Felix has termed the parish clergyman «the first line of defense in mental health,» and stated that he represents an untapped resource for the early detection, referral, and treatment of persons and families in community mental health.

As with any non-traumatic knee injury, if your physician suspects you have plica syndrome the first line of treatment is rest, activity modification, anti-inflammatory medications, and physical therapy to decrease inflammation around the plica.

For some patients, IVF may be a first - line treatment.

And if that is the case... why are drugs the first line of treatment for chronic illness?

The first - line treatment for the majority of separation anxiety cases is psychotherapy; cognitive behavioral therapy in particular is used with great success on mild to moderate cases.

In the case of mild postnatal depression, therapies will always be recommended as a first line of treatment as long as there are no previous mental health problems or conditions.

Tricyclics may also cause troublesome effects, and that is why doctors shy away from using them as a first - line treatment.

Quick access to epinephrine, the first - line treatment for a severe or life - threatening allergic reaction, is critical for individuals managing food allergies.

The first line of treatment, when needed, is with prescription oral antifungal lozenges, suspensions, or mouthwashes.

Some physicians consider behavioral management (nonmedication) first - line treatment, followed by medication options if necessary.

«We need to protect what we've got and we need to encourage pharmacists and general practitioners to follow first - line treatment.»

Supporting commercial lines businesses Progress on fixed fees for costs of noise - induced hearing loss claims Support for fair compensation for mesothelioma sufferers Expansion of the Insurance Fraud Bureau's scope to commercial liability Campaigning for solutions fit for our future Our Flood Free Homes campaign Forward thinking policy for data and cyber Engaging Government to support the role of income protection Delivery of Flood Re, a world first solution for affordable flood cover Fighting fraud Partnering with Government on the Insurance Fraud Taskforce Renewing the Insurance Fraud Enforcement Department Securing new insurer access to the DVLA registered owners database Influencing sensible regulation On Solvency II, we: Secured changes to secondary legislation Clarified treatment of deferred tax Negotiated a favourable calibration of the EIOPA's fundamental spread Supporting insurance businesses Pushing for sensible development of global capital standards Securing better targeted tax legislation Managing the impact of international financial reporting standards.

The results from the Cancer Research UK - funded STAMPEDE trial could change the standard of care for men with prostate cancer, making abiraterone a first - line treatment alongside hormone therapy.

While clomiphene is a first - line treatment used to induce ovulation in women with PCOS, it has downsides — namely that in a significant number of women it does not lead to improved ovulation or live births, and if it does induce ovulation, it frequently results in pregnancies with multiples who face much higher negative outcomes including death.

The first - line designation means that some patients will have access to the drug without first having to receive other treatments such as chemotherapy.

Paclitaxel and another chemotherapy drug, carboplatin, are considered standard, first - line treatments for advanced ovarian cancer, experts say, and most patients respond to the drugs initially.

«Ultimately, everyone is hoping it will be a first line of treatment for these types of abdominal cancers,» said Dr. Roby.

«Considering that PDPN is associated with poor prognosis in GBM, CAR T - cell therapy that targets this protein is promising for treatment of patients with relapsed or resistant tumors following first - line chemotherapy,» says Toshihiko Wakabayashi, a coauthor and the chair of Department of Neurosurgery Nagoya University School of Medicine.

First - line TB tests and treatments in the developing world have not changed for over 30 years.

Instead, immune therapies are the first line of treatment.

Ozanimod is a novel, oral, selective sphingosine 1 - phosphate 1 (S1PR1) and 5 (S1PR5) receptor modulator, and was compared to the first - line treatment, Avonex ® (interferon beta - 1a)(IFN), in patients with relapsing multiple sclerosis (RMS).

She is the first of six people lined up for the landmark treatment, developed by Masayo Takahashi and her colleagues at the RIKEN Center for Developmental Biology in Kobe, Japan.

The ability to identify those patients unlikely to respond to first - line biologic anti-TNF therapies prior to their treatment would allow these patients to be prescribed alternative therapies, providing faster relief of symptoms and reducing the risk of future complications.

«Our results do not support the addition of corticosteroid to antihistamines as a first - line treatment of uncomplicated acute hives.