Sentences with phrase «many genes involved»

Scientists have already begun to pinpoint the genes involved in Huntington's chorea and muscular dystrophy.

In many animal model systems, for example, the precise genes involved in sexual partner selection have been identified, and their neuro - biochemical pathways have been worked out in great detail.

However, Darnovsky points out that the genes involved affect development and metabolism — very much linked to personal identity.

But, as journalist Steve Connor reports, the reference to editing was intentional: «Scientists have used the genome - editing technology to cure adult laboratory mice of an inherited liver disease by correcting a single «letter» of the genetic alphabet which had been mutated in a vital gene involved in liver metabolism.»

ANTI-CIO # 4: In a study performed on rats, rat mothers who were nurturing towards their rat babies (i.e. licked their babies often) produced more growth hormones and changed the chemistry of the DNA in certain genes involved in the offspring's stress response.

We observed strong modulation of key genes involved in lactose synthesis and insulin signaling.

For instance, van't Hof and colleagues (2016) showed recently that the dark colouration of the peppered moth is caused by the insertion of 22,000 bases into the DNA of a gene involved in wing development (Figure 1).

She demonstrated that early experience leads to lasting changes in the molecular structure of the brain and discovered a gene involved in the spread of brain cancer cells into healthy brain tissue.

Wang designed genetic screens that allowed her to find several new genes involved in engulfment.

The new work, says Fitch, is consistent with his prediction — he would love to know the genes involved.

Researchers still have much to learn about the imprinting process and the genes involved, Zhang says, but the discovery of a second mechanism for silencing one copy of these genes underscores imprinting's importance.

A large number of genes involved in nervous system development and function were also deregulated.

According to the study, identifying the lncRNAs that play an unknown role in regulating genes involved in deafness will have an impact.

But the anti-cancer drug romidepsin, a highly potent HDAC inhibitor, turned down the effects of HDAC2, allowing genes involved in neuronal signaling to be expressed normally.

New research at the University at Buffalo reveals the first evidence that it may be possible to use a single compound to alleviate the behavioral symptoms by targeting sets of genes involved in the disease.

Of the genes involved in Parkinson's disease that are present in indicated regions, the strategy captured all but one.

Five genes involved with embryo development differ between wild and domesticated cats, researchers report November 10 in the Proceedings of the National Academy of Sciences.

Crucially, this molecule seems to damp down the activity of a gene involved in glutamate signalling in the brain.

Bernard Friedenson, associate professor of biochemistry and molecular genetics at UIC, looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them.

But when they tried to pinpoint the genes involved, something unexpected happened: they stumbled on C1q, a gene for a protein important in the body's immune system.

«We've known other people who have looked at genes involved in brain size evolution, tested them out and done the same kinds of experiments we've done and come up dry.»

«This paper offers a significant advance in mapping genes involved in disease.

It was deep in the TGF — beta signaling pathway in a gene involved with uvula development.

Such relaxation techniques can boost the activity of genes involved in several processes beneficial to health, and they only take a few minutes each day to show results.

Friedenson thinks that cancer - related viruses that are normally harmless can become dangerous if genes involved in immunity are mutated, either through heredity or environmental causes.

Unravelling the epigenetic control of the lactase gene involved a collaborative effort of CAMH, University of Toronto, the Hospital for Sick Children, Vilnius University and the Lithuanian University of Health Sciences.

Zika induced changes that were more focused on genes involved on DNA replication and repair, indicating that Zika infection disrupts cell replication more.

Comparisons of the Neandertal genome to the genomes of five present - day humans from different parts of the world identify a number of genomic regions that may have been affected by positive selection in ancestral modern humans, including genes involved in metabolism and in cognitive and skeletal development.

An alternative way of tracking dietary changes is to look at the genes involved in digestion.

Killary and colleagues earlier identified a cluster of genes involved in cancer migration and then analyzed the proteins produced by those genes.

For example, the study found down - regulation of genes involved in interferon tau, the major signal of pregnancy recognition.

«In 2010, we unsuccessfully tried testing genes involved in detoxification and concluded that variants in detoxification genes and pathways are less important than previously thought,» says the center's director, Sine Skovbjerg Jakobsen.

Now experiments suggest genes involved in cell stickiness may have given our brain its folds

To identify genes involved in the patterning of adult structures, Gal4 - UAS (upstream activating site) technology was used to visualize patterns of gene expression directly in living flies.

Moreno's first job in the lab — helping a postdoc develop a mutagenesis technique to identify new genes involved in organ development and positioning — earned him a second - author paper in Science just a couple of years into his Ph.D..

Sure enough, plant root cells that harbor fungal arbuscules increase their expression of genes involved in producing such lipids by 3000-fold.

Moreno also found a homologue of a human cancer gene involved in cell competition.

Next, he synthesised 50,000 DNA strands with sequences that almost matched parts of the 24 genes involved in lycopene production, but with a range of variations that he hoped would affect the amount of lycopene produced.

The center is now planning a study to look at genes involved in sensitization in the brain, to see if they are activated in chemically sensitive individuals.

Such analyses have tied Alzheimer's risk to several genes involved in innate immunity — the body's immediate defenses that indiscriminately attack pathogens and other foreign molecules and cells.

They did this by testing tissue concentrations of fatty acids in liver, muscle and brain tissue, along with the expression of genes involved in regulating EPA status and its physiological benefits.

Its altered form moves to the nucleus, where it increases the activity of a gene involved in metastasis (The Journal of Clinical Investigation, DOI: 10.1172 / JCI40433).

So we sequenced a gene involved in cell growth and found a correlation in about 85 percent of the patients: If you had a certain mutation in the EGFR gene, you responded to the drug; if you didn't have the mutation, you didn't.

The activity of genes involved in cholesterol production in the hypothalamus — an area involved in the brain's energy maintenance — was reduced by 25 per cent in both groups of diabetic mice.

But because sponges lack the genes involved in expelling molecules, it was assumed that this was not a functional organ.

Toshihiro Sassa and Takashi Murayama, the first and second authors of the paper, respectively, say, «we would like to identify the other genes involved in downstream signaling from this calcium channel to understand how the signal leads to aversion to high pH.» Sensing alkaline environments is only the first step; the worm must then quickly react to the stimulus by moving away.

They then used a genetic technique called quantitative trait locus analysis to search for the genes involved in generating phenolics in the most promising progeny.

Genes involved in mammary gland development and function had variants associated with greater milk production, perhaps indicating that the Scythians milked their horses.

For example, genes involved in suppressing tumor formation are turned off via epigenetic mechanisms, and genes involved in rapid growth and replication are turned on too high.

Gore's team shows that the silencing of the eye genes is due to the increased activity of a specific gene involved in methylation, Futuyma points out.