Sentences with phrase «many glaucomatous»

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy.

Overall, this simple technique (see figure for overview) produces therapeutically relevant cells in a safe and efficacious manner, which may be used in in vitro models for the investigation of glaucoma disease mechanisms, RGC development, drug testing, and may in the future lead to a treatment of glaucomatous neuropathy.

Review of «Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy» from Stem Cells by Stuart P. Atkinson

We discovered in the laboratory, our lab and others, that mitochondria — these are the little energy powerhouses inside the cells, inside all cells including retinal ganglion cells — they fragment and stop moving in retinal ganglion cell axons very early in glaucomatous insults.

I have been working in the field of glaucoma research, on pathophysiology and diagnostics, for the past 18 years, and have become increasingly interested in the use of advanced imaging techniques for characterization of glaucomatous changes within the retina and optic nerve head.

The published paper concluded that» «molecular alterations detected in the ocular hypertensive human retina as opposed to previously detected alterations in human donor retinas with clinically manifest glaucoma suggest that proteome alterations determine the individual threshold to tolerate the ocular hypertension - induced tissue stress or convert to glaucomatous neurodegeneration when intrinsic adaptive / protective responses are overwhelmed.»

W. Daniel Stamer, PhD Duke University Eye Center, Durham, NC Funded by The Alcon Foundation Project: Role of Exosomes in Glaucomatous Lamina Cribrosa Remodeling

These proteins, if their roles in neuroprotection in the retina are fully established in the future by more comprehensive studies, may present novel therapeutic targets in treating retinal disorders including glaucomatous conditions.»

Tara Tovar - Vidales, MS, PhD University of North Texas Health Science Center, Fort Worth, TX Funded by The Alcon Foundation Project: Role of microRNAs (miRNAs) in Pathologic Fibrosis in the Glaucomatous Optic Nerve Head

Glaucomatous optic nerve injury involves early astrocyte reactivity and late oligodendrocyte loss.

Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T cell - derived Fas - ligand Wax, M.B., Tezel, G., Yang, J., Peng, G., Patil, R.V., Agarwal, N., Sappington, R.M. & Calkins, D.J. (2008) Journal of Neuroscience, 28:12085 - 12096.

Marsh - Armstrong N, Cox E, Soto I. (2008) Gamma synuclein changes cellular distribution in glaucomatous DBA / 2J mice (Investigative Ophthalmology & Visual Science, 49: ARVO E-Abstract 5490).

Soto, I., Son, J., Marsh - Armstrong, N (2008) Proliferation and Oligodendrocyte Turnover in Optic Nerves of Glaucomatous DBA / 2J Mice.

Metabolic Vulnerability Disposes Retinal Ganglion Cell Axons to Dysfunction in a Model of Glaucomatous Degeneration Baltan, S., Inman DM., Danilov, CA., Morrison, RS., Horner, PJ.

AIM We determined the relationship between vascular risk factors and structural glaucomatous

Association of blood and ocular perfusion pressure with structural glaucomatous progression by flicker chronoscopy.

BACKGROUND Vascular risk factors have been associated with glaucomatous visual field progression.

Owner Responsibilities: Although we expect to gain the majority of information from your dog in a single visit, we may want to do additional tests if your dog has a glaucomatous attack.

The best options for a blind, glaucomatous eye are intraocular prosthesis, enucleation, or intraocular injection (ciliary ablation).

Because Golden Retrievers are wonderful, uncomplaining dogs, they will not usually let their owners know that their glaucomatous eyes are bothering them.