Sentences with phrase «many human prostate»
Introducing human prostate cancer cell lines into mice, Wu and his colleagues saw a particular enzyme called MAOA activate a cascade of signals that made it easier for tumor cells to invade and grow in bone.
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The researchers have yet to show the same pathway is active in human prostate cancers.
FRESH insight into prostate cancer has come in a study showing that the mitochondrial DNA of human prostate cancer cells is riddled with mutations.
Coffin described how lab workers there had transplanted human prostate tumor cells into an immune - deficient lab mouse, a common procedure for procuring a colony of cells, or a human cell line, for further study.
The researchers showed that cabazitaxel worked better than docetaxel in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.
«Plant oil suppresses viability of human prostate cancer cells.»
Dr. Steven R. Goodman, Editor - in - Chief of Experimental Biology and Medicine, said «This study by Huanbiao Mo and colleagues at the Texas Woman's University and UT Southwestern Medical Center demonstrates that geranylgeraniol causes dose dependent apoptotic death of human prostate carcinoma cells.
Importantly this article suggests that geranylgeraniol deserves further study as a potential therapy for human prostate cancer.»
A team of researchers in Germany and Denmark led by Steven Johnsen, Professor at the University Medical Center Göttingen, Germany, used human prostate cancer cell lines and depleted them of the DNA - binding protein CHD1.
According to McCague, «the rarity of human prostate cancer cell cultures makes studying tamandron's potential difficult in the test tube.»
It also shrank human prostate cells by 21 per cent.
Next, the researchers tested the effects of RK - 33 and radiation in mice that had been injected with human prostate cancer cells that highly express DDX3.
In preclinical experiments using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and division.
«BPA increases risk of cancer in human prostate tissue, study shows.»
Preliminary work already indicates that a small population of CD117 cells exists in the human prostate.
«Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day - to - day lives, increases the risk for prostate cancer in human prostate tissue,» Prins said.
Signs of cancer developed in the human prostate tissue in a third of the mice fed BPA, as compared to only 12 percent in mice that had not been fed BPA.
The tissue was then allowed to mature for a month into a human prostate - like tissue.
Early exposure to BPA (bisphenol A)-- an additive commonly found in plastic water bottles and soup can liners — causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins.
Prins investigated the effect of BPA on human cells by implanting human prostate stem cells taken from deceased young - adult men into mice.
Prins took human prostate stem cells from deceased young adult male organ donors and implanted the cells into mice, where they formed human prostate tissue.
The new findings show that human prostate tissue is also susceptible.
In both laboratory dishes and mice with human prostate cancers, the nanoparticles proved extremely effective.
Tadashi Matsuda of Hokkaido University and his colleagues in Japan investigated human prostate cancer cells to determine if there is an unknown up - regulation mechanism in the EGFR pathway.
As recent data suggest, PSMA is an important cancer antigen expressed on many human prostate, bladder, renal as well as ovarian cancers, so additional study of the possible benefits of this therapy are important.»
11C - sarcosine also produced high - contrast images in a human prostate cancer case.
Development of a bioengineered model to quantitatively measure the tumorigenic properties of cancer - associated fibroblasts in human prostate cancer.
Although persistent loss of IGF - 1R expression ultimately induced cell stasis and death, both of these processes are regulated by the tumor suppressor gene p53 that is commonly mutated in human prostate cancers.
Androgen - regulated expression of arginase 1, arginase 2 and interleukin - 8 in human prostate cancer.
The Carboxyl Tail of Connexin32 Regulates Gap Junction Assembly in Human Prostate and Pancreatic Cancer Cells.
Species - specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone.
Immunohistochemical analysis of paraffin - embedded human prostate carcinoma using unpurified ab32518 at 1/50 dilution.
A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer - associated fibroblasts in human prostate cancer.
Immunohistochemical staining of paraffinembedded human prostate cancer using P2RX7 antibody (11144 -1-AP) at a dilution of 1:50 (10x objective).
A novel indium -111-labeled gonadotropin - releasing hormone peptide for human prostate cancer imaging.
, van Boxtel, R., Wongvipat, J., Dowling, C.M., Gao, D., Begthel, H., Sachs, N., Vries, R.G., Cuppen, E., Chen, Y., Sawyers, C.L., Clevers, H.C. Identification of multipotent luminal progenitor cells in human prostate organoid cultures.
In a series of lab experiments with cell lines, human xenograft tumors in mice and primary human prostate cancer samples, the researchers demonstrated that miR - 34a inhibits prostate cancer stem cells by suppressing CD44.
STAT5 promotes metastasis of human prostate cancer cells (46) and has been implicated in the resistance of metastatic breast cancer cells to targeted therapies (47).
The DAXX co-repressor is directly recruited to active regulatory elements genome - wide to regulate autophagy programs in a model of human prostate cancer
Preclinical efficacy of growth hormone - releasing hormone antagonists for androgen - dependent and castration - resistant human prostate cancer.
XMRV was initially isolated from the tissues of prostate cancer patients [1] and subsequently found to be present in 6 — 27 % of human prostate cancer cases [2].
«Theranostics» Simultaneously Kill and Image Prostate Cancer Cells Experimenting with human prostate cancer cells and mice, cancer - imaging experts developed a method for finding and killing malignant cells while sparing healthy ones.
On the basis of studies on the XMRV - producing human prostate cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mice.
We identified known and putative TSGs in multiple cancer types and validated the functional and clinical relevance of several promising candidates for human prostate cancer.
All slides mounted with FFPE human prostate cancer tissue sections were baked at 56 °C for 4 hours to fix the tissue onto the slides and were then stored at room temperature.
In 2011, Paprotka, et al. reported that XMRV likely originated through recombination between 2 endogenous murine retroviruses, PreXMRV - 1 and PreXMRV - 2, during in vivo passaging of the human prostate cancer xenograft CWR - R1, resulting in establishment of the XMRV - infected 22Rv1 cell line [38].
The test involves aggregating human prostate cancer cells into microtissues in 96 - well plates and monitoring their growth over 90 days.
Expression of RANKL / RANK / OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation.
«Effect of whey protein isolate on intracellular glutathione and oxidant - induced cell death in human prostate epithelial cells.»
«Capsaicin inhibits the growth of human prostate cancer cells in petri dishes and mice,» said lead researcher Dr. H. Phillip Koeffler, director of hematology and oncology at Cedars - Sinai Medical Center and a professor of medicine at the University of California, Los Angeles.