Sentences with phrase «many influenza strains»

A part of the research will include analyzing exactly why this year's flu vaccine proved so ineffective against the most common strains circulating (the shot was just 25 % effective against influenza A strains).

At that time scientists knew that antibodies from people infected by the 1968 pandemic virus also reacted with an influenza strain isolated in 1963 from flu - ridden ducks.

In 1980 Fiers first sequenced the gene for hemagglutinin derived from the human influenza strain H3N2 that circulated in 1965.

«Even when the vaccine is not a perfect match to the circulating influenza strain, as is the case this year, the vaccine still helps prevent more severe infections if children get sick with the flu,» she says.

Each year, scientists create an influenza (flu) vaccine that protects against a few specific influenza strains that researchers predict are going to be the most common during that year.

Scientists have already synthesized the genomes of the poliovirus and the 1918 influenza strain, and molecular biologist Anthony Forster of Vanderbilt University acknowledges that safety is always a concern.

Scientists may be able to create a «universal» vaccine that can provide broad protection against numerous influenza strains, including those that could cause future pandemics.

In a series of experiments, the researchers found that 95 % of mice vaccinated with the investigational cocktail were protected against a lethal challenge with eight different influenza strains expressing seven different influenza A subtypes, compared to only 5 % of mice who received mock vaccinations.

Alf Hamann, from Deutsches Rheuma - Forschungszentrum and Charité Universitätsmedizin Berlin, Germany, and colleagues, did a comprehensive analysis of IL - 27 function in mice infected with a highly pathogenic influenza strain.

Highly pathogenic (dangerous) influenza strains elicit a strong immune response which can lead to uncontrolled inflammation in the lung and potentially fatal lung injury.

It is widely noted that influenza strains vary each year.

A migratory waterfowl carrying multiple influenza strains nudged another bird, one with a different cocktail of influenza, and the viruses swapped pieces of genetic code in a process called reassortment.

Pandemic flu continues to threaten public health, especially in the wake of the recent emergence of an H7N9 low pathogenic avian influenza strain in humans.

There are several steps between an influenza strain's emergence from its natural animal host and a large - scale human outbreak.

Potential pandemic influenza strain H7N9's gracile structure is captured in a negatively stained transmission electron migrograph (TEM).

Modus operandi: The 2009 H1N1 strain is worrisome because, like the 1918 influenza, it appeared to be more lethal in young adults than most influenza strains.

However, even in previous years when the vaccine has been well - matched to circulating influenza strains, effectiveness has been low (40 to 60 percent).

«Different influenza strains are predominant in different parts of the world and the strains themselves behave differently.

Many individual studies have looked at how effective the available vaccines were at preventing illness and hospitalisation caused by the pandemic influenza strain but up until now no - one has summarised all the available data.

Image courtesy of Vmenkov / Wikimedia Commons After public outcry against research into avian flu strains that can be transmitted among mammals, 40 of the top scientists working on the influenza strains signed a voluntary moratorium on research last January.

► Last month, Science's news department reported an incident in March in which the U.S. Centers for Disease Control and Prevention (CDC) sent the U.S. Department of Agriculture a sample of low - pathogenicity H9N2 avian influenza that was contaminated by deadly H5N1 avian influenza strain.

«That is not enough for a country that seems to be a natural bioreactor for influenza strains,» says Michael Greger, director of public health and animal agriculture at the Humane Society of the United States.

The H5N1 avian influenza strain developed strong resistance to oseltamivir, better known as Tamiflu, in two Vietnamese patients who died from the virus early this year, according to a new study.

The findings highlight a novel way to generate antibodies that recognize and target proteins shared by most influenza A strains rather than those unique to each strain.

Genetic analysis shows that the virus is a mix of avian and swine viruses from North America, a swine flu strain usually seen in Asia, and a human influenza strain.

Severity is tricky to define as it includes everything from the virulence of a particular influenza strain to the vulnerability of a particular population and its ability to respond, Fukuda said, which means it can differ from place to place.

Four European countries have ordered a vaccine tailor - made for the new H1N1 influenza strain by GlaxoSmithKline.

Then, in a 2011 paper in Science, immunologist Antonio Lanzavecchia at the Institute for Research in Biomedicine in Bellinzona, Switzerland, reported isolating a rare «broadly neutralizing antibody,» able to fight off many influenza strains.

A proactive infection prevention plan implemented widely in a Hong Kong healthcare system was a significant factor preventing the spread of influenza strain A H7N9, otherwise known as Avian flu.

Teijaro adds that the ideal approach may be to combine the HIS virus vaccine with a strategy to generate broadly neutralizing antibodies — those that can bind many different influenza strains — to create a universal flu vaccine (SN: 10/28/17, p. 18).

Besser said officials were already taking preliminary steps toward manufacturing a vaccine against the influenza strain responsible for swine flu.

But «the breadth of protection against numerous influenza strains was not investigated here,» and will be important work for the future, he says.

Mice vaccinated with the newly designed influenza virus, called hyper - interferon - sensitive (HIS) virus, survived exposure to lethal doses of several different influenza A strains.

► Also on Thursday, Martin Enserink provided an update on virologist Ron Fouchier, who for the past 3 years «has battled the Dutch government over a fundamental question in the balance between academic freedom and biosecurity: Did he need a government license to publish his hotly debated gain - of - function (GOF) studies on the H5N1 influenza strain?»

Sasisekharan and colleagues are now doing a similar genetic study of H5 influenza strains.

The Medical Systems Virology group at FIMM, together with collaborators has recently sequenced genomes of 135 pH1N1 influenza strains isolated from Finnish patients in 2009 - 2013 and found one Tamiflu - resistant strain from the 2012 - 2013 epidemic season.

In the past two years, genetic sequence information of the flu - virus protein hemagglutinin from only two influenza strains from India has been deposited into publicly available influenza databases, making it difficult to determine exactly which strain is causing the new outbreak, and how it differs from previous strains.

The creation of novel, transmissible, virulent influenza strains is exceptionally risky and has little public health benefit; such research should be stopped.

And because this is such a fundamental piece of the viral machinery, not only are the versions in the different influenza strains very similar to each other, but they also hold many similarities to their counterparts in related viruses such as lassa, hanta, rabies or ebola.

The result is often a new influenza strain born with genetic information from multiple parental strains.

AMSTERDAM — For more than 3 years, virologist Ron Fouchier has battled the Dutch government over a fundamental question in the balance between academic freedom and biosecurity: Did he need a government license to publish his hotly debated gain - of - function (GOF) studies on the H5N1 influenza strain?

The letter states that the pause potentially applies to six projects that range from studying the ecology of avian flu in live bird markets in Colombia to looking at drug - resistance mutations in seasonal influenza strains.

World Health Organization (WHO) is responsible for predicting the influenza strains that will be most common during the next season and for giving recommendations on the particular virus strains that should be used for producing the vaccines for the next influenza season.

But the so - called pause also applies to GOF work on any influenza strain and two coronaviruses, MERS and SARS.

In an ambitious study, the authors attempt to trace drug resistance against all strains of the flu by using an extensive influenza virus database containing all known genetic sequence information (70,000 complete nucleotide sequences) for influenza strains.

The agency also pledged to immediately release newly generated flu sequence information from now on — including data on the dangerous H5N1 avian influenza strain, should it arrive in the United States.

The debate continues about two papers that resulted in H5N1 influenza strains that are more easily transmissible between mammals and may have the potential to trigger a pandemic.

What many feared and some predicted has happened: The H5N1 avian influenza strain has reached Africa.

Widespread use of an over-the-counter product containing amantadine may have caused the H3N2 influenza strain to lose its sensitivity to the drug.

Tests there revealed it was contaminated with the highly virulent H5N1 avian influenza strain, which can infect and sicken humans.