Sentences with phrase «many new tumors»

So even if a tumor is surgically removed, it is difficult to extract every cancerous cell; any left behind will result in the growth of a new tumor.

Four days before Lent, I hold a tried and true friend's hand and she takes off her wig and looks me straight in the eye when she tells me that this new tumor's inoperable and this will be her Cancer 2.0.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

Published in the February 27 issue of Cell, the study found that tumor cells that reach the brain — and successfully grow into new tumors — hug capillaries and express specific proteins that overcome the brain's natural defense against metastatic invasion.

And how do occasional cells survive in this vulnerable state — sometimes hiding out in the brain for years — to eventually spawn new tumors?

Comparing the metastasized tumors with the original breast tumors, the researchers were surprised to learn that multiple, slightly genetically different cells from the original site had broken away together and established the new tumors.

Next steps for this research will see new refinements in the endomicroscope instrument and development of new tumor cell stains and probes that light up the tumor cells to an even greater degree.

The initial experiments made use of cancer cells that Quiñones - Hinojosa and his team removed from willing patients and grew in the laboratory until they formed little spheres of cells, termed oncospheres, likely to be the most resistant to chemotherapy and radiation, and capable of creating new tumors.

It is well established that melanoma cells can spread through the blood to accumulate and form new tumors (metastases) in other parts of the body away from the original tumor.

There is increasing evidence that this is due to the presence of cancer stem cells — cells that reproduce indefinitely and may seed new tumors.

They find that the cells can remain dormant during chemotherapy that kills off most of the cancer and can give rise to new tumors once the drug treatment stops.

Some scientists have blamed so - called cancer stem cells, a subset of cancer cells that might be able to remain dormant, evading chemotherapy or radiation treatments, only to form new tumors months or years later.

«Some cells that we call cancer stem cells adopt deadly characteristics where they can travel through the bloodstream to other tissue and form new tumors.

Only a small portion of cancer cells can form new tumors or metastases, and these are called «cancer stem cells.»

«New tumor analysis method identifies high - risk prostate cancer: Cancer cells» genetic pathways show which patients are likely to develop aggressive types of the disease.»

Metastasis is the process in which cells from a primary tumor break - off, enter the blood stream and create new tumors elsewhere in the body.

Studies have shown that stress might promote cancer indirectly by weakening the immune system's anti-tumor defense or by encouraging new tumor - feeding blood vessels to form.

This allows cancer cells to break off from tumors, spread throughout the body (in blood or other fluid) and form new tumors at distant sites — a process called metastasis.

On the safety side, the panelists delved into the possible risks of injecting genetically modified cells into patients, including the potential for deadly viral infections, brain toxicity, and, paradoxically, the growth of new tumors brought about by CAR - T cells years after treatment.

And while the altered protein also contributed to the growth of already - present tumors, it did not trigger the spontaneous development of new tumors.

Singlet oxygen tends to rip apart tumor cells in a manner that exposes many new tumor antigens to immune cells called dendritic cells, which, like police executing a dragnet, grab the antigens and present them to T cells for closer inspection.

«Blocking known cancer driver unexpectedly reveals a new tumor - promoting pathway: Targeting both pathways with drug inhibitors more effective in stopping colorectal cancer growth.»

This could help eliminate the residual cancer cells that often form new tumors following surgery.

«This combination of features means that the drugs can not only attack the main tumor site, but are more likely to find and attach themselves to tumor cells circulating in the bloodstream — essentially attacking new tumors before they start,» says Quanyin Hu, lead author of the paper and a Ph.D. student in the joint biomedical engineering program.

CellSearch is used primarily to check the progress of cancer treatment, whereas U.C.L.A.'s imaging technology could find cancerous cells at an earlier stage, before they can form a new tumor.

When the two relapsed patients in Wu's study received a PD - 1 inhibitor, their new tumors vanished.

This allowed them to map a «family tree» of the changes happening at a genetic level as the disease spreads, forms new tumors, and becomes resistant to treatment.

«A new tumor suppressor gene for breast cancer in mice.»

The team also found that these genes had different functions in promoting metastasis: One group encouraged growth of tumor cells in both breast and lungs, whereas the other only helped the new tumor thrive in the lungs.

Applying their technique to head and neck cancers, they've discovered seven new tumor - suppressor genes whose role in cancer was previously unknown.

The safe use of a stem - cell - based therapy against brain metastasis would require preventing the engineered cells from persisting within the brain, where they could affect normal tissue and possibly give rise to new tumors.

Rose is currently awaiting results from a new round of mice in development using newer tumor cells.

In cancer, however, this process can produce invasive and mobile cells that can pass through membranes and travel to distant sites, where they seed new tumors.

Both microRNA families have the connection to drug resistance as well as to cancer stem cells, sub-population of cancer cells that have self - renewal properties and the ability to give rise to new tumors that are more resistant to current therapy.

«Circulating tumor cells (CTCs) have been shed by the original tumor and entered the bloodstream — they can then form into new tumors if they lodge in distant tissue,» Wang says.

Yongwon Choi, with Ralph Steinman and others, identifies a new tumor necrosis factor family member TRANCE (later called RANKL), [i] and subsequently demonstrates its role in the immune and bone system, and also in bone - residing cancers such as multiple myelomas.

Just as adults might not stay healthy if they only ate liquid baby formula, new tumors have a different set of requirements than more mature, established cancers to thrive and spread.

Metastasis is a dangerous phenomenon in which cancer cells separate from the original tumor, move into the bloodstream or lymphatic system, anchor in a distant tissue or organ, and begin a new tumor.

CXCR4 is a receptor that cancer cells use like antennae to feel their way from their parent tumor to distinct sites in the body where they will establish a new tumor.

The CSC theory suggests that such CSCs persist in tumors as a distinct population and cause relapse and metastasis by giving rise to new tumors [8 — 10].

The aggressive basal - type breast cancers often metastasize, seeding new tumors in distant parts of the body.

«In a setting with so much diversity, those cells could multiply to form new tumors, which would be resistant to standard treatments.»

Metastatic disease refers to cancer that has spread through the blood or lymph system to form new tumors in other parts of the body distinct from the original site.

It is defined as the complete disappearance of all tumors identified at the beginning of the trial, as well as any new tumors.

At the same time, new tumor entities have been identified that can not be defined histologically.

We validated ZBTB20, CELF2, PARD3, AKAP13 and WAC, which were identified by our screens in multiple cancer types, as new tumor suppressor genes in prostate cancer.

If they are not completely destroyed they are capable of continuous differentiation, they able to self renew and create new tumor colonies.

Since her treatment back then, she has been diagnosed with a couple of new tumors, and she's now starting a new chemo.

In the laboratory animal study, ursolic acid, the active compound in holy basil, combined with radiation was more effective at inducing skin cancer cell death and inhibiting new tumors from forming than radiation alone.

The new tumors, although uncommon, are more difficult to treat.