Sentences with phrase «many of the diseases»

During the session, a trio of experts discussed the opportunities and challenges of a more globalized world, including cross-border clinical trials, the spread of disease and emerging pathogens and managing supply chains.
To try and stop the spread of disease, scientists have started looking into how to quell mosquito populations.
The changing of the food chain around the world has dramatically changed the onset of diseases
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
Tehrani targeted the most conservative companies in the business, ones that had no presence in a particular class of disease targets, to entice those who might jump on the bandwagon later.
Not surprisingly, the spread of diseases (not to mention unhealthy lifestyles that lead to diseases) on a global level is much easier than coordinating care, managing supply chains and clinical trials and rolling out treatments.
«It is our hope that by targeting people earlier, we will have a better chance of delaying or preventing the onset of the disease,» said BAI director Dr. Pierre N. Tariot in a statement.
Darzalex, however, has not yet reached its peak potential as the drug moves into earlier stages of the disease and is being tested on solid tumours like lung cancer.
Eric Dolan, co-founder of software company Neutun Labs, is clear about the importance of the disease that led him to become an entrepreneur.
A study of increases or decreases in rates of a disease across years, calculated for groups of people, is called an ecologic study.
The Texas - based company created a virus - zapping robot that can effectively stop the spread of the disease by using light to disinfect contaminated rooms.
The Chinese government financed nationwide studies into cockroaches» medical value that, after more than two decades of laboratory investigation and clinical trials, had discovered or confirmed dozens of disease - fighting proteins and biochemical compounds with huge potential value in medicine.
Danish pharma company Novo Nordisk (nvo), best known for its insulin - based treatments for diabetes, said Tuesday it's going to shift its focus slightly to fighting obesity, one of the primary causes of that disease.
Newfoundland and Labrador also has some of the highest per capita rates of a number of diseases, including colon cancer, diabetes, and psoriasis.
Brian Cheng, executive director at NWS Holdings, said: «We believe Medopad will succeed in revolutionizing the current convoluted methods of disease treatment and prevention into a more succinct ecosystem with the development of its artificial intelligence and big data gathering capabilities.»
Congress's failure to resolve the Zika funding impasse may reflect a larger political reality: Most Americans just don't care about it or else feel they are safe from the possible spread of the disease.
It is, in short, a giant iceberg of disease that keeps getting bigger.
If that is the case, some people will need an «open procedure,» Brightman told INSIDER, depending on their level of scarring and the nature of their disease.
Traditional lab companies like Quest have also started talking about using blood tests for a personalized medicine approach to the early detection of diseases.
It's a fascinating story and one that offers hope that we can not only make progress against a litany of diseases, but also — just maybe — begin to reverse our soaring national health bill.
Study after study overwhelmingly suggests that a quick cat nap (even 10 minutes helps) can boost brain activity, enhance concentration, support creativity and even reduce the risk of disease.
And Marathon barely did any actual clinical legwork to get the drug cleared for Duchenne — it relied on 1990 - era clinical trial data before tacking on just enough study material to win an approval that doesn't even address the root cause of the disease.
These smells can be signs of disease or infection.
«Procrastination is one of the most common and deadliest of diseases and its toll on success and happiness is heavy.»
Founder and CEO Social Capital LP and Golden State Warriors Owner Chamath Palihapitiya has a mission which is, «To advance humanity by solving the world's hardest problems including the advancement of human capital, the eradication of disease, solutions to global climate change, and other really difficult things that are non obvious.»
A stronger immune system: Another study found that taking daily cold showers increases the number of disease - fighting white blood cells.
BenevolentAI created a bioscience machine «brain» that uses algorithms and data to locate the cause of diseases and generate insights into them that humans otherwise couldn't.
But I was also curious to see what kind of diseases I might be at risk of passing down to my kids and whether the health concerns that run in my family could be spotted in my spit.
Her mother died a few years ago, the father of her two - year - old died of the disease shortly after their daughter was born.
The risk of disease recurrence in a five - year time period also must be greater than or equal to 30 percent.
This means that in the global fight against malaria, we need to do everything we can to slow the rise of drug - resistant forms of the disease.
Glen Macdonald, president of the Wealth & Giving Forum, said there could even be a backlash against the bucket challenge because the serious message of a disease is getting lost in all the stunts and videos.
Production shifted from the island of Oahu to the main Hawaiian island in the 1960s to escape the spread of the disease, which is transmitted by insects.
«When you have these low levels of disease, or no disease at all, it's the best time to get your body to destroy the cancer,» Stanton told CNBC.
'» As part of that effort Marsh is studying the ecosystem of disease — identifying the factors, like hopelessness and isolation, that are at the root of health problems.
And while some, like a 2013 study in the journal The Lancet and a 2015 paper in the journal Nature, have yielded promising clues, none have been able to spot any precise, reliable genetic markers of the disease.
There are only four drugs that have been approved to treat the symptoms of the disease, and the most recent drug approval happened in 2003.
The growing number of people who have the disease is troubling, because there are only four approved drugs that treat symptoms of the disease, and several hopeful treatments have failed key studies in 2017.
But they may have limitations because of their disease,» Bertolini told Fortune editor - in - chief Clifton Leaf during a one - on - one interview.
Sub-Saharan Africa, a region of endemic poverty, has 11 % of the world's population, 24 % of the world's burden of disease, and less than 5 % of its health workforce, said Gottlieb.
At a very simplified level, the cause of the diseases might hold the biggest clue.
It's entirely symptomatic; what you feel inside — that brew of emotions that people often lack the vocabulary to describe — is the measure of the disease.
(Though it's important to note that the treatment, Mitsubishi Tanabe Pharma America's Radicava, is mightily expensive and only treats symptom progression rather than the root cause of the disease.)
While the pill is still in its experimental stage — the company has said it could take up to 10 years for the pill to be prescribed, the AP reports — this technology has the potential to dramatically transform the way we diagnose and treat a host of diseases, most notably cancer.
«Patients and their families can't freeze the progress of a disease while the FDA waits to fill critical positions.»
Studies — including at least one clinical trial with 100 participants — have found that this diet can significantly alter signs of disease, reduce weight and body fat, lower blood pressure, decrease levels of biomarkers associated with cancer, and improve blood - sugar levels.
Gene therapy is, in essence, a type of biotechnology that replaces mutated genes with healthy ones, reversing the effects of disease or damage.
Insufficient or poor - quality sleep has been shown to wreck short term memory, cause weight gain, and increase the risk of diseases ranging from depression to cancer.
Precision medicine is the «cure» piece, but even that isn't possible if we don't move the intervention curve closer and accurately predict and prevent early enough in the progression of disease
As a result, there may be a time lag in reporting the spread of disease locally.
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