Sentences with phrase «many older drugs»

But the real issue on pricing is the year - on - year rises on old drugs — the deflection is to talk about new drug prices, but the sleight of hand is on the double digit rises taken every year on the portfolio staples.

The investigation targets Valeant Pharmaceuticals and Turing Pharmaceuticals, two of the biggest offenders of price hikes on older drugs.

On Thursday, Bristol - Myers Squibb abruptly ditched an accelerated approval application for a combo of its rival immunotherapy Opdivo and an older drug called Yervoy.

As lawmakers and the public scrutinize dramatic price increases for other old drugs — most recently with the Mylan - owned EpiPen, which saw its cost go up by 500 % in the past nine years — the next flash point may be insulin, a drug both ubiquitous and complicated.

In 2011 he started a pharma called Retrophin, which repeatedly raised the prices of old drugs.

While Yervoy brought in $ 960 million in sales in 2013 (an enormous figure for a two - year - old drug with a small patient population), the company currently has more than 35 ongoing clinical trials investigating another drug that disengages the immune system's brakes: the much - awaited nivolumab, which was also from the Medarex portfolio.

But these two older drugs, frequently used in emergency and intensive care situations, have no direct alternatives.

«While we understand a steady, rational increase in prices, it is the sudden, unfounded price explosions in select older drugs that hinder us in caring for patients,» Fogel told the committee.

February 2015: Launches new company, Turing Pharmaceuticals, which acquires an old drug and jacks up their prices.

Specialists in infectious disease are protesting a gigantic overnight increase in the price of a 62 - year - old drug that is the standard of care for treating a life - threatening parasitic infection.

EKR is getting its old drug back for a song.

While most of the attention on pharmaceutical prices has been on new drugs for diseases like cancer, hepatitis C and high cholesterol, there is also growing concern about huge price increases on older drugs, some of them generic, that have long been mainstays of treatment.

Adapt, which is based in Dublin, but operates out of Radnor, Pennsylvania, is one of a handful of companies that in recent years have introduced products delivering naloxone, a decades - old drug that can quickly reverse an opioid overdose, in Narcan spray.

But what Sequoia married itself to was an offshore drug company that borrowed heavily to buy other drug companies, cut costs and research, then raised prices on many older drugs to astronomical heights.

It quadrupled the price of a 55 - year - old drug that treats a rare genetic disorder.

Within weeks of the deal, Valeant went from investor idol to pariah as its business model of buying older drugs and raising the prices attracted international scorn.

I'd rather have a socialist pope than a capitalist pope, and who cares what a bitter old drug addict thinks anyway?

He was haunted by the murder of two kids he had grown close to and by the words of a 12 - year - old drug trafficker who told him, «I'm going to die young, but I'm going to live well.»

His old drug partners barely even recognized him.

The gratingly privileged 37 - year - old drug pusher, scion of Hollywood Oscar - winning royalty — son of Michael Douglas, grandson of Kirk...

Lithium — a simple metal and the oldest drug in psychiatry — might protect the brain against mental illness, Alzheimer's, and other diseases.

Unlike the older drugs, however, they do not involve antiquated steps, such as growing live flu viruses in fresh, fertilized hens» eggs and then inactivating the virus.

«An old drug can be used in a new way.»

This is an important step for determining whether the new drug is a better option than existing, older drugs.»

They hope to use Auroanofin to pave the way for discovering new uses for other old drugs.

Rice and team have been able to invigorate older drugs from the penicillin family by combining them with BPEI.

Charles Rice, principal investigator and professor in the Department of Chemistry and Biochemistry, OU College of Arts and Sciences, with team members Robert Cichewicz and Daniel Glatzhofer, both OU chemistry professors, has been able to invigorate older drugs from the penicillin family by combining them with BPEI.

Old drug, new use?

Old drugs often get a surprising second life.

Researchers at the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine have developed a computer program to find new indications for old drugs.

«Computer program finds new uses for old drugs: Researchers repurpose pain meds to kill cancer cells.»

Now, many companies are flocking to the same drug targets, which means that the first of a kind to be approved won't enjoy a monopoly for as long as older drugs did.

You know that older drugs, such as haloperidol, work well, but a third of all schizophrenia patients who take it suffer from Parkinsonian - like symptoms, such as tremors, involuntary spasms, and uncontrollable facial movements.

Though Shkreli is best known for hiking the price of a decades - old drug by 5,000 percent when he led Turing Pharmaceuticals, this trial related to an entirely different matter: Ponzi - like fraud.

And a new antibiotic can not compete with older drugs that are off - patent and therefore cheap, until bacterial resistance makes the old drugs useless.

Two newer epilepsy drugs may not harm the thinking skills or IQs of school - aged children whose mothers took them while pregnant — but an older drug is linked to cognitive problems in children, especially if their mothers took high doses — according to new research from The University of Manchester.

NEW ORLEANS, LOUISIANA — It's far from the ideal therapy, but scientists say a new combination of two old drugs is an important step forward in the fight against sleeping sickness, a long - neglected tropical disease.

«Recently, interest in re-using old drugs to treat new diseases has increased as a way to develop new therapies more quickly.

«Drug - target database lets researchers match old drugs to new uses.»

A group of new drugs against malaria does more than just kill parasites; it may also restore the efficacy of a generation of older drugs called quinolines to which parasites around the world have become resistant.

Dondorp's study showed that compared with an older drug called quinine, a new one called artesunate reduces the risk of death from severe malaria in African children by 23 % — a finding that could save tens or even hundreds of thousands of lives annually.

Researchers are also looking at new uses for old drugs — trying to prevent Alzheimer's using ibuprofen, for example.

«Back to the future: Most efficient option for treating unexplained infertility: An inexpensive 50 - year - old drug proves just as effective as more recent reproductive hormones.»

A single dose of a century - old drug has eliminated autism symptoms in adult mice with an experimental form of the disorder.

The finding also calls attention to the special medical needs of older drug users — a group that, until now, hasn't garnered much notice.

In today's issue of Science Translational Medicine, he and his colleagues present a more efficient way of finding such new uses for old drugs: by bringing together data on how diseases and drugs affect the activity of the roughly 30,000 genes in a human cell.

«Age - old malaria treatment found to improve nanoparticle delivery to tumors: Nanomedicine researchers find new use for 70 - year - old drug.»

Covalently binding drugs include old drugs such as aspirin and penicillin, as well as powerful new enzyme inhibitor drugs for treating cancers.

Multi-targeted therapy of cancer by niclosamide: A new application for an old drug.

(Thalomid) Thalidomide is an old drug, though it has not been widely available since the 1960s, when it was found to cause birth defects.