Whereas scientists generally agree that there are anywhere from four to nine basic tastes, there are thousands upon thousands of distinct aromas, only a single molecule of which you need to light up one or more of our hundreds of
olfactory receptors.
Humans have around 10,000
olfactory receptors.
A baby in the cradle carry is too far removed from your main
olfactory receptors and an important way of bonding is lost.
Olfactory receptors are closely connected to memory, even more than any other sense.
In Nick's case, the cause was probably catastrophic damage to
his olfactory receptor neurons.
Lurking within the mucus of the nose are the tips of
olfactory receptor cells.
Another risk stems from the fact that
our olfactory receptor neurons dangle down into our nostrils, leaving them exposed to damage from environmental toxins and infections.
Dogs have more types of
olfactory receptor than we do — but as Mainland points out, cows have more than dogs (about 1,200 compared with 800) and it's not clear that cows are significantly better at smelling.
The researchers identified more than 1000
olfactory receptors in the soft - shell turtle, which is one of the largest numbers ever to be found in a non-mammalian vertebrate.
But as we get older, this process slows, and the patches of nasal tissue without
any olfactory receptors get bigger.
In 2004 the Nobel Prize in Physiology or Medicine went to Linda B. Buck and Richard Axel for their research showing that there is a huge family of genes that encode proteins called
olfactory receptors.
There are many thousands of olfactory sensory neurons expressing any particular
olfactory receptor.
Therefore, the wine activates a complex pattern of olfactory sensory neurons by engaging each of
their olfactory receptor proteins, which recognize these different features.
Toxicants like solvents, pesticides or volatile molecules from oil spills can travel straight into the brain via
the olfactory receptors — nasal neurons that number in the many millions, thickly studding the inner lining of the nose.
McRae and colleagues found that the genetic variants associated all lie in or near genes that encode so - called odorant or
olfactory receptors.
In contrast, the typical person's nose has 400
olfactory receptors.
In the case of SISSA's Neurobiology Laboratory, the focus was on the genes of
olfactory receptors which, surprisingly, are also present in the cells that synthesise dopamine and that die in Parkinson's disease.
The team uses a computer - controlled pneumatic pump to administer an odor puff to the locust, which has
olfactory receptor neurons in its antennae, similar to sensory neurons in our nose.
But now a new study, published in Frontiers in Physiology, has found two
olfactory receptors in human lung tissue.
«At the beginning of the experiment we did not expect that
the olfactory receptors would have completely different effects.»
No one had previously suspected that
olfactory receptors would be present in airways past the nasal cavity.
«Function of
olfactory receptor in the human heart identified: The new findings may be relevant in the long term for diabetic patients and patients with increased heart rates.»
Regardless, sniffing out this unexpected function of
an olfactory receptor may inspire exciting new medical developments.
It was always thought that
olfactory receptors» sole bodily function was to smell, and could only be found inside a nose.
New study has found two
olfactory receptors in human lung tissue.»
Future studies will seek to identify how Ggamma13 interacts with other molecules within
the olfactory receptor.
«This could be a consequence of the limited variety of scents to be found in the arid, alpine meadow environment, but that doesn't explain why the yak, a species that also inhabits the Tibetan Plateau, has an increased number of
olfactory receptor genes compared with cattle,» Dr Subramanian said.
After analyzing the genes of about a thousand bats, the researchers studied the exact composition of the MHC genes as well as the molecular structure of three families of
olfactory receptor genes: TAAR2, TAAR3 and TAAR8.
Mice engineered to be lacking the Ggamma13 protein in
their olfactory receptors were functionally anosmic — unable to smell.
Together, the findings demonstrate that Ggamma13 is essential for mammals to smell odors and extend the current understanding of how
olfactory receptor cells communicate information about odors to the brain.
Dogs can do that because their noses contain 900 different types of
olfactory receptors, chemical detectors in cells that respond to many different kinds of odor molecules in particular ways.
Many volatile compounds can now be detected quite well by «electronic noses» that were inspired by
the olfactory receptors of animals and provide characteristic chemical fingerprints for scents and mixtures of scents.
«To fully understand the loss of
olfactory receptor genes in the ground tit, further comparisons need to be made with genomes of closely related species inhabiting lower altitudes.»
First, they sequenced the same 50
olfactory receptor genes from two humans, two chimpanzees, two gorillas, two orangutans, and two rhesus macaques.
At least we haven't lost
the olfactory receptors that respond to the scent of roses.
«New method for exhaustively isolating
olfactory receptors responding to specific odorants: Step toward the elucidation of a mechanism for recognizing odorants in mammals.»
Related sites PNAS paper Human
Olfactory Receptor Database Exploratorium (HORDE) Yoav Gilad's home page
A research group led by Osaka University and Panasonic Corporation developed a method for making a prompt, exhaustive isolation of
olfactory receptors (ORs) responding to the odorant of interest.
Methyl laurate is also detected by another sensory neuron type that expresses
the olfactory receptor Or88a.
The compound is detected by a neuron which expresses
the olfactory receptor Or47b; this receptor responds exclusively to methyl laurate.
Flies which lack
the olfactory receptor Or47b are still attracted by the odor of other flies; however, their mating behavior is considerably reduced.
More broadly, a better grasp of how
olfactory receptor sensitivity depends on chemical structure could reveal universal secrets of receptor function, Firestein adds.
Furthermore, the same pheromone - specific neuron types which activate
the olfactory receptors Or47b or Or88a respond to methyl laurate.
Flies which lack
the olfactory receptor Or88a are no longer attracted to fly - specific odors; however, their mating behavior is uninhibited.
As all three studied insect species emerged at different times in insect evolution, the scientists wanted to track the historical development of
olfactory receptors.
Christine Mißbach, first author of the study, analyzed the active genes in the insect antennae where
the olfactory receptors are located and describes her discovery this way: «Astonishingly, the firebrat, which is more closely related to flying insects, employs several co-receptors, while the odorant receptors themselves are absent.»
In the cultivated cells, the team detected a number of typical
olfactory receptors.
They form a functional complex with another protein, the so - called
olfactory receptor co-receptor, which enables insects to smell the tiniest amounts of odor molecules in their environment very rapidly.
Next, the researchers tested whether neurons in the insects»
olfactory receptors, or sensilla, responded to nonanal.
Damage to
the olfactory receptor neurons because of a respiratory infection, a head injury or a neurodegenerative disease can disrupt the brain's ability to process different smells.