Sentences with phrase «many other cancer types»

«This puts the existing U.S. bladder cancer approval in serious doubt, and will also, of course, raise market concerns about Tecentriq's efficacy in other cancer types,» Kepler Cheuvreux analyst David Evans wrote in a note to investors.

Celgene's lead product, Revlimid, a drug designed to treat multiple myeloma and a few other cancer types, has been benefiting from longer duration of use, strong pricing power, and high multiple myeloma market share.

The Lund researchers have already started new studies in which a larger number of women will be monitored from breast cancer diagnosis and onwards, as well as testing ctDNA methods in other cancer types.

It will, therefore, be very interesting and potentially promising if similar effects are seen in other cancer types, such as lung cancer,» Balkwill noted.

The findings may be applicable to other cancer types such as lung cancer or melanoma, they say.

The genes that affect hair colour also affect other cancer types, while other pigment genes affect the chances of having Crohn's and other forms of bowel disease.

Using Epiviz and Bioconductor, the research team found consistent regions of DNA methylation changes in colon cancer samples generated by the public Cancer Genome Atlas project and similar gene expression in these regions of DNA methylation changes in other cancer types.

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

The team also found that there were also cases of other cancer types in families with these hereditary mutations such as leukemias and brain tumours.

«While there is understandable excitement around new therapies that enlist the immune system to fight cancer, we are still in a situation where greater than half of patients don't respond in melanoma and the response rate is even worse in other cancer types,» Hanks said.

For this purpose, the researchers used the computational tool IMPACT, developed in the Tan lab, to sort functional from missense mutations and to cross-reference candidate mutations with those previously reported in other cancer types.

Following the ovarian cancer analysis, the team expanded the study to include other cancer types.

The researchers» next steps will involve expansion of the biomarkers identified in this study to other cancer types, especially breast cancer, due to the hormonal input that is a common factor in gynecologic tumors.

«We would also like to determine if this combination is effective against other cancer types.»

To explore this idea, Hopkins oncologists Dung Le, Luis Diaz, and others looked for mismatch repair mutations in tumor samples from patients with advanced colon cancer and other cancer types whose tumors had stopped responding to other treatments.

Confirmation of the biomarkers in other cancer types will facilitate further characterization and validation to provide mechanistic understanding of how and why these specific gene - targets become modulated to accentuate or inhibit tumor metastasis.

The researchers» study also found that, compared with patients with other cancer types, patients with breast cancer were 3.7 times less likely to develop PTSD at six months, but not at four years.

«The next step of our work will see how this approach works in other cancer types, and we hope it could ultimately lead to testing this technique in trials to see if it can help patients.»

«What we think this might mean is that these de novo, new, genetic changes may be more relevant to early onset cancers with an impact on fertility,» says Stadler, since testicular cancers more often occur during reproductively active years than the other cancer types.

For example, HPV - inactive tumors were 17 times more likely to contain TP53 gene mutations — which are common in other cancer types — than HPV - active cervical cancers.

In addition, the study, led by investigators in The Cancer Genome Atlas (TCGA) Research Network, revealed four novel tumor subtypes, while also identifying genomic similarities between endometrial and other cancer types, including breast, ovarian, and colorectal cancers.

The company is developing CAR T - cell immunotherapies for multiple myeloma, prostate and other cancer types, as well as gene therapies for orphan diseases.

Additionally, the compound they have developed allows them to profile other cancer types and see if they are dependent on BFL - 1 for their survival.

FOXA1 activation, inducing enhancer reprogramming that endows a cancer cell with metastatic properties, is an epigenetic mechanism, as opposed to a genetic one, that explains at least one mechanism of metastasis in this form of pancreatic cancer, and likely, other cancer types as well.

Other Cancers: Distribution of Other Cancer Types in Arab States; Basal Cell Carcinoma (Qatar), Basal Cell Nevus Syndrome (Egypt), Becker Nevus Syndrome (Saudi Arabia)...

Despite being less funded than many other cancer types, exciting diagnostic and treatment advances are beginning to emerge; however, more rapid progress is needed.

«This heralds a new era in cancer treatment which is potentially revolutionary as it is likely similar techniques can be used in other cancer types.

As the biomarker literature becomes more expansive in other cancer types, Dr. Petty and his team aim to expand their work to other forms of cancer.

The tumor suppressor, which could be useful as a biomarker to help diagnose and monitor treatment for liver cancer, could also be relevant for other cancer types.

GSK3β, the first neighbour of β - catenin is a central, highly multi-functional protein known as a key protein difficult to inhibit without causing side effects and toxicity.41 In glioblastoma and NSCLC cancer, previous studies found that the decreased level of FRAT1 influences the GSK3β activity to phosphorylate β - catenin and by that, inhibit the WNT pathway.39, 40 The role of FRAT1 in colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3d).

Unlike other cancer types, prostate cancer sometimes grows very slowly.

While history, physical exam, and X-rays often suggest a diagnosis of bone cancer, bone biopsy is the only way of truly confirming diagnosis, and differentiating primary bone tumors from other cancer types.

In some situations, these tumors are hard to tell apart from other cancer types.

The most common cancer types were breast (8), lung (3) and prostate (3), with other cancer types including endometrial, lymphoma, ovarian, rectal and renal cancer.

Not exact matches

In the most recent of these reports (in the latest issue of Science), Dr. Jennifer Wargo, a surgeon and research scientist at M.D. Anderson, along with several dozen colleagues at other institutions, reveal that the composition of a patient's gut microbiota can significantly influence whether he or she responds to an immune checkpoint inhibitor — the type of cancer immunotherapy that releases the emergency brakes in the car analogy above.

Other times, certain types of cancer appear to be the source.

Novartis and Gilead Sciences already received the first two approvals of CAR T for other types of cancer.

Among others, he's invested in the cervical cancer screening tool MobileODT and Biomeme, which claims to do genetic testing for certain types of diseases within an hour.

There's still much more work to do with other types of cancer, but the overall trajectory is pointing in the right direction.

Effective PARP inhibitors are particularly sought after by drugmakers because of their potential to be used in combination with other types of cancer treatments to create new breakthroughs in treatments.

The two companies plan to develop drugs to fight multiple cancer types, either alone or in combination with their other cancer treatments.

While it has shown promise for some types of tumors and become standard of care for others, researchers are just beginning to explore how different immunotherapy technologies can be applied to brain cancer.

The act of breastfeeding, designed by God to sustain new life, imparts protection to the mother from certain types of cancer and other diseases.

Studies also show a strong link between other types of cancer and processed meats.

Crisco is very unhealthy — it's highly processed, hydrogenated and contains trans fats which have been linked to cancer, type 2 diabetes, hardening of the arteries, stroke, immune dysfunction and a whole host of other diseases.

It is also used with surgery and other medicines for managing certain types of thyroid cancer.

American Lung Association www.lungusa.org/stop-smoking/ Information about lung cancer, asthma and other types of lung ailments.

Other benefits of breastfeeding for mothers include protection against some types of cancers and osteoporosis.

Other fish oil benefits that may have made it popular include claims to help ADHD, asthma, arthritis, abnormal heart rhythms, and that it may help prevent some types of cancer.

Studies show that children who are not breastfed have higher rates of mortality, meningitis, some types of cancers, asthma and other respiratory illnesses, bacterial and viral infections, ear infections, juvenile diabetes, some chronic liver diseases, allergies and obesity.