In all, the work provides a roadmap that can be applied to
other human diseases, according to Zhu.
«The vector used in these studies is one that has already been used in the treatment of
other human diseases so this is a promising approach.»
The results of this original study are highly relevant to
other human diseases that dependent on genome instability, such as fungal infection or cancer, and open new venues for anti-leishmanial drug discovery using host - directed strategies that target the parasite's metabolic dependence on the host cell, thus preventing the adaptive evolution of drug resistant parasites.
So a tropical species like Aedes aegypti, which transmits Zika, dengue, and
other human diseases, could expand its range northward in the United States as temperatures warm.
Aedes aegypti is the mosquito that carries dengue and several
other human diseases, including Zika.
«Our findings strongly implicate LGR4 in the pathogenesis of osteoporosis as well as various
other human diseases, including certain cancers,» said study lead author Kari Stefánsson, M.D., Dr. Med., President of deCODE Genetics.
The scientists, from Nanjing University, say they also intend to create dog models of muscular dystrophy, Parkinson's and
other human diseases.
The Speicher laboratory uses proteomics, metabolomics, computational methods, and biophysical approaches to characterize the roles of normal and mutant proteins in cancers and
other human diseases.
Not exact matches
Founder and CEO Social Capital LP and Golden State Warriors Owner Chamath Palihapitiya has a mission which is, «To advance humanity by solving the world's hardest problems including the advancement of
human capital, the eradication of
disease, solutions to global climate change, and
other really difficult things that are non obvious.»
Andrew Batholomaeus, a consultant toxicologist at Australia's University of Canberra and the University of Queensland, states that «the potential
human health consequences of discouraging the use of pyriproxyfen in drinking water storage and
other mosquito - reduction programs is catastrophic with potential deaths and serious
disease from otherwise avoidable malaria, dengue and
other mosquito - borne
diseases numbered in at least the hundreds of thousands.»
By treating biology as software and reprogramming cells to treat
diseases and
other ailments,
humans have already made tremendous progress in medicine, Kurzweil said Sunday.
Every
human being is on the same level... homosexuals and heterosexuals and all
others... including those with syndromes or
diseases or malformed... We're all on equal footing in our fallen state.
The struggle is against a system of Corporate Power profiting from hunger to pharmaceuticals for
disease and
other forms of
human wants.
Today the two horrors are becoming antibiotic - resistant, and AIDS, herpes, chlamydia, genital warts,
human papilloma virus, and more than a dozen
other sexually transmitted
diseases, most of them formerly rare, are ravaging the population.
Stem cells can transform into any
other human cells, so they have immense potential for generating all sorts of adult cells and thus can be used in research concerning
human degenerative (and
other)
diseases.
With the advances in knowledge that are almost certain to be gained from the
Human Genome Initiative — or, if its critics should win the day and it lose support, from more piecemeal genetic - research — we will know more and - more about genetic factors causally related to health and
disease and to
other important aspects of life, such as intelligence and emotional states.
All
human beings face death as an inevitable destiny, but those of us who are crippled by heart
disease or cerebral injury or
other illness are more conscious of this destiny, particularly as we advance in years.
On the
other hand, the techniques of postcivilization also offer us the possibility of a society in which the major sources of
human misery have been eliminated, a society in which there will be no war, poverty, or
disease, and in which a large majority of
human beings will be able to live out their lives in relative freedom from most of the ills which now oppress a major part of mankind.
so often they just look at potential markers — but those don't always equate to
diseases)- what was the health of the those being studied - I'm assuming the test subjects were people, but
other studies done on animal subjects might not be as reliable as those done on
humans.
Human breast milk that is frozen or stored for longer than 48 hours loses a significant amount of its antioxidant content, making it less able to help infants fight off free radicals that play a role in allowing infections and
other diseases.
And, it is not only nutritious, but
human milk contains
other substances that keep children healthy and help them to fight off
diseases and infections.
«The resistance to
disease that
human milk affords a baby can not be duplicated in any
other way,» the authors scold.
However, «The AAP Section on Breastfeeding, American College of Obstetricians and Gynecologists, American Academy of Family Physicians, Academy of Breastfeeding Medicine, World Health Organization, United Nations Children's Fund, and many
other health organizations recommend exclusive breastfeeding for the first 6 months of life.2, 127 — 130 Exclusive breastfeeding is defined as an infant's consumption of
human milk with no supplementation of any type (no water, no juice, no nonhuman milk, and no foods) except for vitamins, minerals, and medications.131 Exclusive breastfeeding has been shown to provide improved protection against many
diseases and to increase the likelihood of continued breastfeeding for at least the first year of life.
These include the infant with galactosemia, 53,54 the infant whose mother uses illegal drugs, 55 the infant whose mother has untreated active tuberculosis, and the infant in the United States whose mother has been infected with the
human immunodeficiency virus.56, 57 In countries with populations at increased risk for
other infectious
diseases and nutritional deficiencies resulting in infant death, the mortality risks associated with not breastfeeding may outweigh the possible risks of acquiring
human immunodeficiency virus infection.58 Although most prescribed and over-the-counter medications are safe for the breastfed infant, there are a few medications that mothers may need to take that may make it necessary to interrupt breastfeeding temporarily.
Research in the United States, Canada, Europe, and
other developed countries, among predominantly middle - class populations, provides strong evidence that
human milk feeding decreases the incidence and / or severity of diarrhea,1 - 5 lower respiratory infection,6 - 9 otitis media,3,10 - 14bacteremia, 15,16 bacterial meningitis, 15,17 botulism, 18 urinary tract infection, 19 and necrotizing enterocolitis.20, 21 There are a number of studies that show a possible protective effect of
human milk feeding against sudden infant death syndrome,22 - 24insulin - dependent diabetes mellitus,25 - 27 Crohn's
disease, 28,29 ulcerative colitis, 29 lymphoma, 30,31 allergic diseases,32 - 34 and
other chronic digestive diseases.35 - 37 Breastfeeding has also been related to possible enhancement of cognitive development.38, 39
Excessive and unnecessary use of the drugs, which are similar to what doctors prescribe for people's ear infections, strep throats and
other illnesses, can lead to super-resistant strains of bacteria that can cause serious
human diseases that have no cure.
These and
other food allergens implicated in atopic
disease, such as egg and peanut, can be detected in
human breast milk 4 hours after maternal intake and remain in the milk for several days (20).
Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis
disease or are
human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of
other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from
other breast if clear of lesions).
Physiologic sleep studies have found that breastfed infants are more easily aroused from sleep than their formula - fed counterparts.247, 248 In addition, breastfeeding results in a decreased incidence of diarrhea, upper and lower respiratory infections, and
other infectious
diseases249 that are associated with an increased vulnerability to SIDS and provides overall immune system benefits from maternal antibodies and micronutrients in
human milk.250, 251 Exclusive breastfeeding for 6 months has been found to be more protective against infectious
diseases compared with exclusive breastfeeding to 4 months of age and partial breastfeeding thereafter.249
When we are faced with incurable congenital
diseases, when our fellow
human beings are afflicted with cancer, diabetes, tumours, arthritis, damaged organs and
other body parts, and many
others, I believe a miracle is indispensable.
Capra and
others have evidence that Neandertal versions of genes make
humans more prone to some
diseases (SN: 3/5/16, p. 18).
«But in this case, when this virus infects cells, the virus makes its own transcription factors, and those sit on the
human genome at lupus risk variants (and at the variants for
other diseases) and that's what we suspect is increasing risk for the
disease.»
The stocks are helping the development of new countermeasures such as drugs, vaccines and diagnostics in case smallpox should reappear, and may also allow researchers to explore the impact of smallpox on the
human immune system, providing insights into
other diseases such as AIDS.
Mid-career and more senior Franklin Fellows, both sponsored and self - nominated, work on global issues of vital importance to the United States, such as the environment; counterterrorism;
human rights; consular matters; international development assistance; HIV / AIDS and
other trans - national
diseases; trade, energy and financial policy; and many
others.
The behavioral tests used here modeled one dimension of the
disease — an inability to experience pleasure from normal activities — but not
others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in
humans, he says.
One has not yet been tested in
humans and the
other has not made it through all the mandatory stages of testing to ensure it is effective at preventing the
disease.
Several species of mammal, including mice, rats and dogs, are able to sniff out
disease in
humans and
other animals.
One piece of evidence is the fact that leprosy is a strict
human disease without
other hosts or reservoirs.
Reductions in biodiversity from illegal wildlife trade can have
other substantial negative
human health impacts, including the loss of potential sources of pharmaceuticals, experimental models for studying
disease, crop pollination and micronutrients for
humans lacking alternative sources of protein.
It causes the
disease tularemia in
humans, rabbits and rodents, among
others.
An inflammatory protein that triggers a pregnant mouse's immune response to an infection or
other disease appears to cause brain injury in her fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and
humans, new Johns Hopkins - led research suggests.
He carried one genetic mutation that in modern
humans raises the risk of coronary heart
disease by 40 per cent, and two
others that made him prone to a build - up of fat in the linings of his arteries.
Preliminary results of the study were presented at a World Health Organization (WHO) evidence review group meeting, while UNITAID has issued a call for further research into the use of endectocide class drugs, of which ivermectin is currently the only one registered for
human use, as new vector control tools in the fight against malaria and
other mosquito borne
disease.
• In
other funding news, the National Institutes of Health announced a new $ 17 million program to investigate whether extracellular RNA plays an important signaling role in people, and whether it can be harnessed to diagnose and treat
human diseases, Mitch Leslie reports in News & Analysis.
If further studies in
humans prove successful, this research could have broad implications for the prevention of influenza and, by extension, as an approach for
other infectious
diseases as well.
«Healthy gut bacterial communities are known to benefit immune regulation, metabolism and potentially even the nervous system, so if cholera or
other diarrheal
diseases permanently impact the microbiota, there could be long - term effects on
human health,» explains Regina LaRocque, MD, MPH, of the Massachusetts General Hospital (MGH) Division of Infectious
Diseases, co-senior author of the paper.
Humans might be able to direct gene drives to kill only female mosquitoes (the ones that bite and spread
disease), or render the insects incapable of carrying malaria, dengue or
other diseases.
The most serious forms of the
disease are caused by Plasmodium falciparum and Plasmodium vivax, but
other related species (Plasmodium ovale and Plasmodium malariae) can also infect
humans.
The study was done with rodent malaria, but the researchers, at Pennsylvania State University in University Park, expect the pattern to apply to
human malaria and possibly to
other mosquito - borne
diseases such as dengue fever and West Nile virus.
After all,
other humans are all potential
disease - carriers, says Valerie Curtis, director of the Hygiene Centre at the London School of Hygiene and Tropical Medicine.