Sentences with phrase «many ovarian tumors»

According to Merck Manual, the ovary would also be completely removed if an ovarian tumor is present.

(A BRCA1 mutation predisposes a woman to either breast or ovarian tumors, in some cases both.)

In an earlier Penn Medicine study, 38 percent of all patients (and 46 percent of females with the condition) were found to have a tumor, most commonly it was an ovarian tumor.

It is disproportionately deadly because ovarian tumors tend to flourish while producing few obvious symptoms.

She will be using therapeutic antibodies to dampen the inflammation around ovarian tumors.

One study showed that ovarian tumors produce a signaling molecule that serves to attract regulatory T cells, a subclass of adaptive immune cells responsible for quieting other T cells.

Weisman said it should be possible to noninvasively find small ovarian tumors within rodents used for medical research by linking nanotubes to antibody biomarkers and administering the biomarkers intravenously.

Scientists identified the specific proteins secreted by the parasite Toxoplasma gondii that cause the immune system in mice to attack established ovarian tumors.

Researchers at Rice University's Laboratory for Systems Biology of Human Diseases analyzed the metabolic profiles of hundreds of ovarian tumors and discovered a new test to determine whether ovarian cancer cells have the potential to metastasize.

«We found a striking difference between the metabolic profiles of poorly aggressive and highly aggressive ovarian tumor cells, particularly with respect to their production and use of the amino acid glutamine,» said lead researcher Deepak Nagrath of Rice.

Their results demonstrate that specific rhoptry and dense granule effector proteins that T. gondii secretes before and after host cell invasion, respectively, control the development of an effective host antitumor response, and increase the survival of mice with ovarian tumors.

The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.

As proof - of - principle of the potential efficacy, Zhang's team grew human ovarian tumors in immunocompromised mice, then injected short - interfering RNAs to block the tumors» growth using RNA interference against FAL1.

This new approach to classifying ovarian tumors can help doctors make the right management decisions, which will improve the outcome for women with cancer.

But mutations, which are found in 96 percent of patients with high - grade serous ovarian tumors, can cause p53 to form clumps, or «aggregates,» which impair the protein's normal function.

Ten women underwent surgery based on their ultrasound exams, with four having invasive ovarian cancers, two having ovarian tumors of low malignant potential, one having endometrial cancer, and three having benign ovarian tumors.

Now, MIT engineers have developed a far more sensitive way to reveal ovarian tumors: In tests in mice, they were able to detect tumors composed of nodules smaller than 2 millimeters in diameter.

In humans, colon cancer often spreads to the liver and forms small tumors that are difficult to detect, similar to ovarian tumors.

«New technology can detect tiny ovarian tumors: «Synthetic biomarkers» could be used to diagnose ovarian cancer months earlier than now possible.»

Now, results of a study of nine women suggest that the genomic roots of many ovarian tumors may indeed arise in the fallopian tubes, potentially providing insights into the origin of ovarian cancer and suggesting new ways for prevention and intervention of this disease.

Although CSs comprise only 2 % -5 % of all uterine malignancies and 1 % -2 % of all ovarian tumors, they are responsible for a disproportionate number of deaths due to their high biologic aggressiveness and resistance to standard treatments, such as radiation and chemotherapy.

Led by Ludwig Lausanne investigator Alexandre Harari and George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne, the study shows that ovarian tumors harbor highly reactive killer T cells — which kill infected and cancerous cells — and demonstrates how they can be identified and selectively grown for use in personalized, cell - based immunotherapies.

And a December 2014 study found that ovarian tumors coax adult stem cells into providing key metabolites they need to grow.

In their most intriguing work, they're collaborating on something new: a «theranostic» nanoparticle that can both diagnose and attack ovarian tumors.

The earliest and one of the most striking came from observations that the presence of infiltrating T cells (called «tumor - infiltrating lymphocytes,» or TILs) in ovarian tumors is positively and strongly associated with improved survival of patients with ovarian cancer [1].

After the bulk of the ovarian tumors had been removed, the team projected near - infrared light onto the surgical site.

Hammond has ongoing investigations with both of those labs, work that could lead to a theranostic nanoparticle that simultaneously identifies ovarian tumors and hits them hard.

He previously revealed the existence of spontaneous immune responses in ovarian tumors as well as described how regulatory T cells and tumor blood vessels affect these responses.

Neither normal ovarian tissue nor benign ovarian tumors expressed HGMA2, they found.

The researchers have devised a nanosensor that breaks apart in the presence of ovarian tumor cells and sheds fragments of itself.

Among these and other results integrating multiple platforms, it's apparent that Basal subtype tumors more closely resemble ovarian tumors than other breast cancer subtypes.

Research Interests: Mechanisms of immune regulation in the breast and ovarian tumor microenvironment

Do most ovarian tumors harbor this defect?

Growth inhibition of ovarian tumor - initiating cells by niclosamide.

Claudin - 4 activity in ovarian tumor cell apoptosis resistance and migration.

Coukos, who is currently leading an ovarian cancer clinical trial sponsored by CRI's Clinical Accelerator, sought to understand why PD - 1 / PD - L1 immunotherapies are often ineffective for these patients, even though ovarian tumors are often infiltrated by «killer» T cells that recognize tumor - specific neoantigens and express high levels of PD - 1.

They all had a type of ovarian tumor called a teratoma.

iPSC - NKs themselves have already shown efficacy in the battle against leukemia and HIV infection [4, 5] and so researchers from the laboratory of Dan S. Kaufman (University of Minnesota, USA) aimed to assess their anti-tumorigenic capabilities against ovarian tumors [6].

This means things like ovarian tumors and Cushing's disease have the potential to cause similar symptoms.

Long term side effects may include increased risk of ovarian tumors.

MD Anderson cancer center uses about 4 tablespoons of flax seeds daily to significantly lower testosterone in their patients with androgen secreting ovarian tumors.

I have an ovarian tumor in my remaining ovary (other ovary remove 4 years ago due to same cause).

Many conditions can lead to naturally high testosterone, including polycystic ovarian syndrome or an ovarian tumor during pregnancy.

«I might expect to see a 25 - pound ovarian tumor, but a 132 - pound tumor is very rare,» said lead surgeon Vaagn Andikyan, MD, a gynecologic oncologist at Danbury Hospital, in a statement.

Spayed and neutered dogs have an increased incidence of mammary, testicular and ovarian tumors, as you might imagine, since these tumors are affected by the hormones.

Human Warnings: Carcinogenesis: Nitrofurazone has been shown to produce mammary tumors in rats and ovarian tumors in mice.

Ultrasonography may also be helpful: it shows possible consolidation in tissues (ovarian tumor or cyst in this case).

Most ovarian tumors are age dependent so an older animal has more risk of developing tumors.

At some stages, ovarian tumors require hormones to enable them to grow.

Granulosa cell and epithelial tumors are the most common ovarian tumors in bitches.