Sentences with phrase «many reactive oxygen»

Curcumin exerts both direct and indirect antioxidant effects by scavenging reactive oxygen species (ROS)(38) and inducing the expression of cytoprotective proteins in an Nrf2 - dependent way (39).
S. Okada, «Iron - induced tissue damage and cancer: the role of reactive oxygen species - free radicals,» Pathology International 46, no. 5 (May 1996): 311 - 32.
Reactive oxygen species, also called free radicals, are chemicals that typically contain oxygen, are known to be found in cigarette smoke, and cause DNA damage in cells.
After 10 days of smoke exposure, the scientists found an overall increase in DNA damage responses to so - called reactive oxygen species within the cells.
«These data are fully in accord with recent work on the actions of reactive oxygen species in cells, although clearly at odds with the popular concept that dietary antioxidants are inevitably beneficial,» says Malcolm Jackson at the University of Liverpool, UK, who was not involved in the research.
Most of the genes are involved in cells» ability to deal with oxidative stress, in which reactive oxygen products of metabolism harm cells.
Ocean water permeating the porous rock of the core could be exposed to ionizing radiation and undergo radiolysis, producing molecular hydrogen and reactive oxygen compounds.
Finally, while the underlying mechanism is unclear, the team found that having reduced NOX2 - derived reactive oxygen species also raised the risk for these autoimmune diseases.
When potent oxygen radical scavengers such as cerium oxide nanoparticles (nanoceria) were combined with a highly charged polymer (polyacrylic acid) and incorporated into extracted chloroplasts using the LEEP process, damage to the chloroplasts from superoxides and other reactive oxygen species was dramatically reduced.
Carbonaceous PM is made up of black carbon, primary organic aerosol (POA) and, especially, secondary organic aerosol (SOA), which is known to contain harmful reactive oxygen species and can damage lung tissue.
One lit up in the presence of hydrogen peroxide, a prominent reactive oxygen species, whereas the other two acted as mitochondrial injury sensors.
Apparently, a side reaction in the respiratory system in the mitochondria causes them to steadily release reactive oxygen species that can damage DNA, RNA and proteins.
The damage sensors lit up first, with the hydrogen peroxide marker following moments later, suggesting that the reactive oxygen molecules are indeed a sign, and not a cause, of injury.
Scientists have long assumed that wounded mitochondria release reactive oxygen molecules, which then damage DNA and proteins, increasing disease risk.
Too many reactive oxygen species can be harmful because they can damage the DNA within our cells.
For decades, researchers have known that reactive oxygen species, or free radicals, can do serious damage to cells and trigger cancer.
Brenner said the NOX family are transmembrane proteins that generate reactive oxygen species (ROS) from oxygen.
In the case of cisplatin - induced hearing loss, kenpaullone appears to protect hair cells by preventing CDK2 from stimulating the production of toxic reactive oxygen species from the cells» mitochondria.
It belongs to a group of chemicals called reactive oxygen species (ROS), which scientists suspect to have a damaging effect on cells and their components.
The immune system may kick in when animals eat, releasing reactive oxygen molecules to kill microbes on food, helping to protect from disease.
But when the lights go on, TAPP becomes active, producing chemicals called reactive oxygen species, or ROS, that rapidly kill the bacteria.
Otherwise, it would be difficult to tell what the «normal» amount of circulating reactive oxygen molecules in the animal's body was.
In medicine, they could also be used to encapsulate oxygen - sensitive active compounds and to reduce the inflammation caused by reactive oxygen species (ROS) in biomedical applications.
The researchers don't yet know the exact chemical reactions that produce the free radicals, but the work «quite solidly establishes a new role for reactive oxygen in development,» says ageing researcher Karl - Heinz Krause of the University of Geneva in Switzerland.
«There was a concept that reactive oxygen species are bad,» he says, «but they can do more than harm cells.»
Insect midgut - dwelling bacteria generate reactive oxygen species that inhibit malaria parasite development.
The find is one of the first signs that such reactive oxygen species can build as well as destroy.
We live in an oxygen - rich atmosphere, and radicals, particularly reactive oxygen species (ROS), are natural by - products of respiration.
Banfi says that the related genes expressed in a variety of tissues suggest that reactive oxygen species will turn up in other surprising roles.
On top of the problem recognition and methodology development, the article in Nature Energy also provides an initial approach to how the storage cell can protect itself from the reactive oxygen species.
It has been theorized that the major cause of bleaching is the result of chloroplast damage due to heat stress, which results in the production of toxic, highly reactive oxygen molecules during photosynthesis.
Essentially, the reactive oxygen molecules that have an extra electron exert a stronger force on the tip than the unreactive ones, and thus we can distinguish them.»
Other plasma - activated solutions have previously been shown to induce reactive oxygen species within cells, but these were not detected in plasma - activated Lactec (PAL)- treated cells, suggesting an alternative mechanism triggered cell death.
The cause of the damage is still poorly understood, but radiation is known to create highly reactive oxygen - containing molecules in the body.
They found that soluble iron in the earliest oceans quickly combined with oxygen to form rust — forming reactive oxygen molecules, which damage biological tissue and make the cyananobacteria grow more slowly and produce less oxygen.
This metabolic demand makes brain cells particularly vulnerable to damage from oxidative stress, in which reactive oxygen species (ROS), sometimes called free radicals, exert toxic effects on cellular components.
This new paper, published in the journal Applied and Environmental Microbiology, demonstrates that MRSA die on copper surfaces by a multifaceted attack from copper ions and reactive oxygen species (ROS).
This fact makes vacuum UV light extremely useful for industrial applications from sterilizing medical devices to cleaning semiconductor substrates because when it strikes oxygen - containing molecules on a surface, it generates highly reactive oxygen radicals, which can completely destroy any microbes contaminating that surface.
Free radicals, otherwise known as reactive oxygen species, are a byproduct of metabolism.
Some experts blame aging on the corrosive capability of chemically reactive oxygen molecules or «oxidants» churned out by mitochondria inside cells.
«Muscles maintain proper function by producing reactive oxygen species at the right time: Study results underscore the importance of having a nuanced view of antioxidants.»
Although reactive oxygen species can damage cells when produced in high amounts, according to a study published online Sept. 5, 2017 by Science Signaling and featured on the journal's cover, these oxidative species are crucial signals that start the process of repairing myofiber.
Geologist Martin Kennedy and his colleagues from the University of California, Riverside realized that clay minerals in marine sediments are responsible for trapping the organic carbon that would otherwise bond with highly reactive oxygen.
One explanation is that the plant sterol diet increased formation of reactive oxygen species in the hippocampus, whereas the Fortasyn diet, which yielded the best results in the spatial memory task, tended to have an opposite effect.
«Our work highlights the need to take a nuanced view of the role of reactive oxygen species, as they are necessary when they are present at the right place and right time.
Mitochondria help injured muscle cells (myofibers) repair by soaking up calcium that enters from the site of injury and using it to trigger increased production of reactive oxygen species.
Colon cancer cells produce proteins, fatty acids, nucleic acids and reactive oxygen species (ROS).
The cells» survival relies on a delicate balance between energy and reactive oxygen species (ROS) production.
«Energy production can also generate reactive chemical species — often referred to as «reactive oxygen species» or «oxidants» — as by - products, which can be damaging to cells.
High glycolytic activity leads to accumulation of toxic reactive oxygen species (ROS), as does rapid manufacture of mitochondria, which tend to leak the same chemicals.
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