Sentences with phrase «many types of immune cells»

So research teams began souping up various types of immune cells and even targeting them to specific protein markers on tumors.

When the team compared the types of immune cells activated in the fetus with those in the mother, there were clear differences, suggesting that fetuses generate an independent immune response to CMV (Journal of Experimental Medicine, DOI: 10.1084 / jem.20090348).

Luznik and his team inventoried types of immune cells present in the blood of bone marrow transplant patients treated with post-transplant cyclophosphamide.

The males also had fewer nerve cells in their brains and their brains contained a type of immune cell that shouldn't be present there.

The scientists zeroed in on a type of immune cell called regulatory T - cells, which were known to suppress autoimmune responses.

Neutrophils are one of the most common types of immune cells and known to engulf microorganisms, but they are not normally associated with peripheral nerve damage, such as that caused by diabetes or trauma.

The cells are a recently discovered type of immune cell called Th17.

This sparked my interest in the role of one type of immune cell — dendritic cells — in GVHD, and I thought this could constitute a postdoc project.

Researchers also found a type of immune cell (multinucleated macrophage giant cells) in the ovaries of reproductively «old» mice only.

One advantage of this method is that it only activates a certain type of immune cell, the dendritic cell or T - cell, and only in one part of the body, near the draining lymph nodes or tumor, which helps cut down on the system - wide side effects often seen with chemotherapy.

OX40 functions as a throttle for T cells, another type of immune cell crucial for battling tumors, and the anti-OX40 antibodies rev up these cells.

Using animal models of precancerous polyps in the bowel, Chung and his team determined that certain types of immune cells within a chronically inflamed intestine can become rewired, causing them — paradoxically — to contribute to disease development rather than protect against it.

Asthma has been correlated with an overabundance of one type of immune cell called M2 macrophages in the lungs.

«A personalised immunotherapy was prepared for each patient by taking a sample of their blood and extracting a particular type of immune cell called dendritic cells.

Blood tests showed that IL - 7 curbed the production of SOCS3 in a type of immune cell called a T - cell, thereby boosting T - cell response.

Antibodies derived from a type of immune cell found in unusually high numbers in HIV - infected individuals with chronically uncontrolled virus levels are less effective at neutralizing HIV than antibodies derived from a different type of immune cell more common in people without HIV, scientists report.

«The ratio of CD4 and another type of immune cell, CD8, which is often abnormally reversed in HIV, normalized.

Immune messenger molecules called cytokines and certain types of immune cells race to the bite site, making it inhospitable for the parasite.

A few years ago, MS researchers were focused on a new type of immune cell called the Th - 17 cell, which appeared to be a key player in driving the neuronal damage in MS. Because Th - 17 cells produce the cytokine IL - 17, researchers likewise thought this chemical was essential to the disease.

The researchers noted that the two studies made strikingly similar findings despite the fact that they focused on different types of immune cells.

Professor Dan Davis and his team at the Manchester Collaborative Centre for Inflammation Research, working in collaboration with global healthcare company GSK, investigated how different types of immune cells communicate with each other — and how they kill cancerous or infected cells.

His group focused on another type of immune cell known as primary macrophages and their response to live bacterial pathogens.

The study goal was to determine if these different trajectories were associated with blood concentrations of eosinophils and neutrophils, two types of immune cells that play a role in many respiratory diseases and are routinely measured during medical evaluations.

In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.

The drug's mechanism of action was entirely new: Instead of attacking cancer cells (like chemo), or indiscriminately revving up the immune system (like IL - 2), ipilimumab blocked a single receptor on one type of immune cell.

The same area has a known role in the development of T - cells, a key type of immune cell.

The ADGRE2 gene provides instructions for production of ADGRE2 protein, which is present on the surface of several types of immune cells, including mast cells.

They were able to follow the activity of the immune cells using time - lapse 3 - D microscopy imaging of fish retinas and found that neutrophils, the type of immune cells that are typically the first responders to tissue injury, were largely unresponsive to photoreceptor death.

The researchers also wanted to revisit the Trojan horse hypothesis, to see if, as had been proposed, infected monocytes, a type of immune cell, might be responsible for carrying the parasite into the brain.

In experiments in mice, UC San Francisco researchers have discovered that regulatory T cells (Tregs; pronounced «tee - regs»), a type of immune cell generally associated with controlling inflammation, directly trigger stem cells in the skin to promote healthy hair growth.

Upon further investigation, they found that IL - 17 was produced by gamma delta T cells, a type of immune cell found in mucosal tissues.

S. mansoni IPSE binds to Immunoglobulin E (IgE), an antibody produced by the immune system that is expressed on the surface of basophils, a type of immune cell; and mast cells, another immune cell that mediates inflammation; and sequesters chemokines, signaling proteins that alert white cells to infection sites.

This study shows that in conditions like toxic shock syndrome, toxins from such bacteria can trigger one type of immune cells (MAIT cells) to turn against the host.

After 3 months, the researchers drew blood samples from the monkeys, purified five different types of immune cells, and measured gene expression across their entire genomes.

Once lymphocytes find such invaders within the lymph node, they destroy them in collaboration with other types of immune cells.

A few years ago, Chawla's group had reported that cold exposure activated macrophages, a type of immune cell, in white adipose tissue.

However, chronic liver inflammation in both mice and humans also led to the accumulation of immunosuppressive lymphocytes, a type of immune cell Karin and Shalapour first described two years ago.

«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.

«Up until now, researchers have focused on T cells — another type of immune cell,» said John J. O'Shea, M.D., scientific director of NIAMS and senior author of the paper.

Their preliminary results identified two types of immune cells, CD4 + and CD8 + T cells, which become mobilized to attack various surface molecules on the TB bacterium.

In patients with severe asthma, however, NK cells are disabled from resolving inflammation, and become outnumbered by other types of immune cells that provoke inflammation.

Moffitt researchers wanted to determine if it would be possible to activate the cancer - fighting properties of T cells indirectly by targeting another type of immune cell called a dendritic cell.

The 1 - 3 millimeter granuloma also contains fibrous and necrotic tissue as well as a number of other types of immune cells, making it an extremely complex structure.

She found that the brain depends on a type of immune cell known as the T cell, which normally kills infected cells or leads other immune cells in a campaign against foreign invaders.

«The ratio of two types of immune cells, CD4 and CD8, which are often abnormally reversed in HIV, normalized, and the HIV - resistant cells even migrated to the gut mucosa, an important site for the virus,» Lalezari says.

In the Dec. 1 issue of Science, the team from the MGH Center for Systems Biology describes a «crosstalk» between lung tumors and bone marrow, which leads to the generation of a type of immune cell that travels to the tumor and promotes its progression.

In the newly published study, Mount Sinai researchers from The Mindich Child Health and Development Institute and the Jaffe Food Allergy Institute report that by counting the numbers of one type of immune cell activated by exposure to a food, a simple, safe blood test can accurately predict the severity of each person's allergic reaction to it.

After they gave birth, she measured the levels and types of immune cells in both the mothers» blood and the babies» umbilical cord blood.

Lymph nodes have microscopic compartments called «follicles,» where they store a specific type of immune cells, the B - cells.

B cells are a type of immune cell that produce antibodies.