Sentences with phrase «many types of tumors»
Novocure's main focus to date has been treating glioblastoma, or GBM, a type of tumor that affects the brain.
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It's wrong for this type of tumor.
While it has shown promise for some types of tumors and become standard of care for others, researchers are just beginning to explore how different immunotherapy technologies can be applied to brain cancer.
... have a protective effect against the development of certain types of tumors.
A couple of doctors assume that those who sleep with eyes open might be a damaged sign of the nerve, the problems related to the thyroid gland, and the various types of tumors.
Different CARs determine what types of tumors T cells target.
Since the cancer cells in both types of tumors were the same, the researchers compared the noncancerous cells present in the induced and transplanted tumors to explore what might be causing the T cell apoptosis.
They found that depending on the cell of origin, mutations in PIK3CA and p53 induced very different types of tumors.
According to the American Brain Tumor Association, this type of tumor is the most common in adults, affecting as many as 300,000 people each year.
«Shifting bacterial communities in the stomach may influence cancer risk: Microbe changes linked with specific conditions could explain differences in risk and type of tumor.»
This bumped up sensitivity and allowed the team to home in on the tissue type of the tumor.
In blood samples from 1005 patients with eight types of tumors that had evidently not yet metastasized, the test detected between 33 % and 98 % of cases, depending on the tumor type (see graph, above).
The authors explain in the article that NSD1 mutation has recently been linked in the scientific literature to the blocking of cellular differentiation and the promotion of oncogenesis in this type of tumor.
Consider Cushing's disease, in which any of several types of tumors produce astronomically high glucocorticoid levels.
Most cancer vaccines developed to date have been designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient with that type of tumor.
Cancer is a heterogeneous disease, with genetic variations occurring between different types of tumors and different patients.
After surgical removal, radiation, and chemotherapy, this type of tumor often returns; drugs are then usually no longer effective.
They report that the test can detect significant drops in the metabolic activity levels of all three types of tumors within 72 hours when exposed to an effective drug whereas tumors that were resistant to a drug show no change.
This is important because tumors are not all alike and some types of tumor cells may respond differently to a specific drug than others, Skala pointed out.
When breast cancer is diagnosed, the drug regimen that the patient receives is based primarily on the results of a biopsy that is used to identify the type of tumor she has.
Glioblastoma is the most aggressive type of tumor that originates in the brain and with no curative treatments currently available, the average survival time for patients ranges from 15 to 18 months.
To streamline this process, Uhlén's team has created standardized arrays containing microscopic samples from 48 kinds of normal human tissue and 20 types of tumors.
In recent years a body of evidence has accumulated to show that chronic inflammation can play an important role in the progression of some types of tumors from a premalignant state to full - blown disease.
That's the nodule type of tumor we saw in the mice with the silenced protein,» said Douglas Kniss, professor of obstetrics and gynecology at Ohio State's Wexner Medical Center and senior author of the study.
These are two pathways that are very commonly mutated in human tumors, and we try to understand where those pathways are mutated, which type of tumors, what are the mutations that co-occur with mutations in those pathways; and try to understand, if we try to inhibit those pathways, what can we expect in patients.
The researchers also note that more investigation is needed to fully understand all the mechanisms by which HOXC10 mediates cell proliferation and death, and the roles it may play in different types of tumors.
«Previous monotherapies have not extended the lifetimes of mice bearing this type of tumor,» Petty said.
If it is malignant, you need to know what type of tumor it is to choose the best treatment and that treatment needs to be carried out by specialist gynaecological cancer surgeon»
Successful treatment depends in part on accurately identifying the type of tumor, but this can be difficult.
As well as identifying the type of tumor, the test expresses the confidence of the diagnosis as a percentage.
The method is fast and inexpensive and should be applicable to other types of tumors than colon cancer.»
She estimates that about 50 percent of women with ovarian cancer have tumors with this type of tumor and would qualify for the trial, which needs about $ 2 million in philanthropic funding before it could begin.
Two case studies provide an important potential new avenue for treatment of these types of tumors, which are resistant to traditional radiation therapies and difficult to manage even with surgery, the current standard of care.
«A number of other types of tumors have been shown to be driven by chimeras, but this one is unique — it codes for a kinase, an enzyme that modifies other proteins, that has not been identified in cancers.»
Undifferentiated iPS cells can form teratomas, a type of tumor.
We believe that each dog breed may correspond to one type of B - or T - cell lymphoma and so studies within and between breeds gives us a unique possibility to understand how the genetic background affects what type of tumor develops, and how its progression is regulated,» says Ingegerd Elvers.
«Our work outlines the genetic similarities of the tissue and cells in different types of tumors and shows the strong relationships mice can have to other human cancers too.»
The Heidelberg epidemiologists now plan to extend their investigation to other types of tumor.
Occurrence of this type of tumor on the tongue is exceedingly rare, says author Dr Manisha Biradar.
Another possibility that Irvine's lab is working on is developing treatments that could be used against tumors even when scientists don't know of a specific vaccine target for that type of tumor.
The analysis of the lymphoma - like cancers was the first proteomic study of this type of tumor.
Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.
The circuit, which can be customized to respond to different types of tumor, is based on the simple AND gates used in electronics.
VIC - 008 is a fusion protein combining an immune - activating protein from the tuberculosis bacteria with a small antibody fragment targeting mesothelin, a protein expressed in several types of tumor — including mesothelioma, pancreatic and ovarian cancer.
What has changed about care for this type of tumor since Sen. Ted Kennedy was diagnosed with it in May 2008?
So it's generally a very aggressive type of tumor.
He adds, «This study was actually a pilot project for a much larger effort within the Center for Molecular Therapeutics to map responses against drug combinations across hundreds of cancer cell lines, not just melanoma, and look for novel combinations that will benefit subsets of patients regardless of the particular type of tumor they have.
The researchers found what they refer to as the mastermind fusion gene — the first fusion gene associated with this type of tumor.
The types of tumor that can be particularly responsive to immunotherapy generally happen in older people, or people who have genetic factors that allow their tumors to acquire a lot of mutations — so that the tumor has a lot of different antigens that are recognized by the immunotherapy.
They found that, in these particular types of tumors, PLK4 regulates tumor growth and the tumor's tendency to metastasize.