Sentences with phrase «many vacuoles»

The self of the twentieth century is a voracious nought which expands like the feeding vacuole of an amoeba seeking to nourish and inform its own nothingness by ingesting new objects in the world but, like a vacuole, only succeeds in emptying them out.

The platelets showed an unusual size and shape, an abnormal structure and excessive vacuoles.

Bacteria (colorized in blue) are located either in the cytosol or within a membrane - bound vacuole.

However, FPs have usage limitations for imaging in low pH environments, such as in acidic organelles, including endosomes, lysosomes, and plant vacuoles.

The larger organelles, such as the nucleus and vacuoles, are easily visible with moderate magnification (although sometimes a clear view requires the application of chemicals that selectively stain parts of the cells); they were among the first biological discoveries made after the invention of the microscope.

The mitochondria circling the vacuole actually fuse together, allowing them to efficiently use nutrients.

The parasite sends out the MAF1 protein to tether the mitochondria to the vacuole, which may be what breaks them apart, giving the parasite the greater share of fatty acids.

With this knowledge, Pernas and colleagues identified the correct parasitic protein that tethers the organelles to the vacuole.

When Toxoplasma infects a mammalian cell, it uses part of the cell's membrane to wrap itself in a little sac, called a vacuole.

A vacuole containing a Toxoplasma parasite is surrounded by mitochondria (indicated by arrows).

Rather, she says, the crystals appear to form because the vacuoles in which they collect are rich in sulfate.

But the crescent - shaped C. moniliferum caught Krejci's eye because of its unusual ability to remove strontium from water, depositing it in crystals that form in subcellular structures known as vacuoles — an knack that could include the radioactive isotope strontium 90.

These bags fuse with other bags, enzyme - rich lysosomes, which are filled with acids that degrade the contents of the vacuoles.

«To prevent arsenic toxicity, we think the fungus put the arsenic in «a safehouse» — storing it in its vacuole — before the toxin gets loaded to the grain,» explained Bais.

Genetically disabling one of those pore - forming proteins, called PPLP2, allows the malaria parasites to break free of the vacuole but keeps them firmly sealed inside the red blood cell, Glushakova and colleagues discovered.

Perhaps they are simply waste, forming by accident in vacuoles that serve as storage depots for sulfate, said Krejci.

When the scientists recently gave mice a single dose of cocaine and looked for signs of autophagy in their brain cells, they detected autophagy - associated proteins and changes in vacuoles in adults and in mouse pups whose mothers had received cocaine while pregnant.

It might also be possible to improve the process by tinkering with sulfate levels in the environment, thereby changing the amount of sulfate in the vacuoles.

The first real clue was the drug's ability to concentrate in the food vacuole — or so - called acid stomach — of the malaria parasite.

By now, some parasites have evolved resistance to the drug: genetic adaptations that allow them to expel chloroquine from their food vacuoles 40 to 50 times faster than their drug - sensitive kin.

The right image shows red spherical bodies of chloroplasts that are removed and mobilized to the vacuole by chlorophagy.

However, the Agriculture Department microbiologist found, the voracious bacteria eaters weren't able to digest their lunch, so they just left it bundled inside the now - protective vacuole.

Ohsumi then used chemicals to induce more mutations in the yeast strains, looking for cells that failed to form visible vacuoles even when they were starving.

Usually yeast vacuoles were too small to see under the light microscope, but in the mutant yeast, they grew so large they were easy to observe.

The Listeria protein snippet apparently prompts the macrophage to obliterate the escaped protein once it's out of the vacuole but before it can get to the macrophage's outer membrane, suggests Patrick Berche, a microbiologist at the Necker Hospital in Paris.

Bright fluorescence was observed in parts considered to be vacuoles in the cells.

«We want to know if the experience of being in this vacuole upregulates a whole set of virulence traits that make the [surviving] bacteria more infectious,» Brandl says.

When they starved the yeast, the scientists found that the cells developed unusually large vacuoles, the cellular garbage dumps that collect materials to be recycled.

But Listeria builds a protein that burns holes in the vacuole membrane, allowing it to escape.

Membrane ruffles surround and engulf extracellular fluid (top panels), creating the spherical intracellular vacuoles seen inside the cell (bottom panels).

This is possible because quinolines are active inside a cell organelle called the digestive vacuole; resistance occurs when the parasite finds ways of keeping the drug out of the vacuole.

And indeed, as more of the eggs filled the screen of the monitor — some fertilized, most not — the cells frequently had large vacuoles, or fluid - filled bubbles, in their interior.

They discerned a u-shaped chain of magnetite within a fluid - filled sac resembling a vacuole of a cell.

Megalencephalic leukoencephalopathy (MLC), caused by mutations in MLC1 and GlialCAM, is a rare disease that entails this type of vacuoles.

It is now clear that mutations in the cancer cell cause the violent ruffling, which leads to a high density of vacuoles (those fluid - filled bubbles visible within the cell).

On the right, you see the plant transporting the dissolved salts sodium and chloride first into the bladder and then in its vacuoles.

For one thing, says Joyce, the paper shows that the organisms appear bloated, and contain large, vacuole - like structures — often a sign of sequestered toxic material.

The HOPS complex facilitates the fusion between MVB and the vacuole.

Current model of endosomal maturation and cargo sorting at the endosome - vacuole interface.

Ltc1 is an ER - localized sterol transporter and a component of ER — mitochondria and ER — vacuole contacts.

Rab8a regulates the exocyst - mediated kiss - and - run discharge of the Dictyostelium contractile vacuole.

«By removing the tip and replacing it with one from shigella, the salmonella didn't dwell inside the vacuoles.

Envelopment of human cytomegalovirus occurs by budding into Golgi - derived vacuole compartments positive for gB, Rab 3, trans - Golgi network 46, and mannosidase II.

Anaplasma phagocytophilum APH0032 is exposed on the cytosolic face of the pathogen - occupied vacuole and co-opts host cell SUMOylation.

As seen in Figure 2, the abnormal BM cells were found to exhibit eccentric, large, round - to - oval / convoluted nuclei with mostly fine chromatin and prominent nucleoli and moderate - to - abundant gray cytoplasm with several cells exhibiting multiple diminutive cytoplasmic vacuoles.

An initial step of GAS - containing autophagosome - like vacuoles formation requires Rab7.

But the researchers uncovered something more — that the business end of the syringe device serves a critical role in directing bacterial traffic, thus controlling whether the bacteria become «chronic dwellers» inside the membrane - bound vacuole or break out into the cell fluid.

«Until now, it wasn't known how these pathogens decide to remain trapped inside a chamber - like vacuole or to move freely in the cellular fluid,» said microbiologist Leigh Knodler of WSU's Paul G. Allen School for Global Animal Health, who co-led the study with Cammie Lesser of Harvard.

Perforin - 2 protects host cells and mice by restricting the vacuole to cytosol transitioning of a bacterial pathogen.

He decided to explore how the vacuole breaks down biomolecules.