Sentences with phrase «map genes in the genome»

The RNA being used to map genes in the genome has been obtained from another of Sally's progeny obtained in 2015.

The RNA being used to map genes in the genome has been obtained from another of Sally's progeny obtained in 2015.

Not exact matches

As the cost for a full gene map approaches $ 1,000, the opportunity increases for business owners to get in on the genome mapping industry.

Then, given your clearly profound understanding of the relevant science, you can explain how humans came to possess a defunct gene for egg - yolk proteins in our placental mammal genomes and why the presence of this dead gene and the mutations rendering it defunct map to the lineages observable in the fossil record?

«Cancer cells disguise themselves by switching off genes, new research reveals: A genome - wide map of the genes switched off in aggressive tumors reveals a «signature».»

In a study published in Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genomIn a study published in Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genomin Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genomin different parts of the tumor, providing a «signature» of these switches throughout the genome.

In this genome - wide association study, researchers found gene variants mapping to five loci associated with intrinsic epigenetic age acceleration (IEAA) and gene variants in three loci associated with extrinsic epigenetic age acceleratioIn this genome - wide association study, researchers found gene variants mapping to five loci associated with intrinsic epigenetic age acceleration (IEAA) and gene variants in three loci associated with extrinsic epigenetic age acceleratioin three loci associated with extrinsic epigenetic age acceleration.

Erwin compares the endeavor to the Human Genome Project, in which scientists mapped the sequence of our genes.

In this month's issue of Genome Research, Elizabeth Stewart and her colleagues at Stanford University present this new map, which places about 8000 landmarks along the genome's 3 billion bases — DNA's building blocks — yielding twice the resolution of gene maps currently in usIn this month's issue of Genome Research, Elizabeth Stewart and her colleagues at Stanford University present this new map, which places about 8000 landmarks along the genome's 3 billion bases — DNA's building blocks — yielding twice the resolution of gene maps currently iGenome Research, Elizabeth Stewart and her colleagues at Stanford University present this new map, which places about 8000 landmarks along the genome's 3 billion bases — DNA's building blocks — yielding twice the resolution of gene maps currently igenome's 3 billion bases — DNA's building blocks — yielding twice the resolution of gene maps currently in usin use.

In a 1995 Science paper, Venter's team sequenced the genome of Mycoplasma genitalium, a sexually transmitted microbe with the smallest genome of any known free - living organism, and mapped its 470 genes.

A comprehensive map of genome - wide gene regulation in Mycobacterium tuberculosis.

And the shared map implies that genes for important characteristics, such as disease resistance, photoperiodism, drought tolerance, storage proteins and the like, can be plucked direct from one genome and applied in another.

Researchers analyzed the genomes of 16 related orange and white tigers in captivity, fully mapping those of the three parent tigers to show that a mutation in one pigment gene called SLC45A2 is at play — the very same gene that drives lighter coloring in people of European ancestry, chickens, and some mice.

«When the genome of the black Perigord truffle was mapped in 2010, we thought that the fungus had sufficient genes to create its flavour on its own,» junior professor Richard Splivallo from the Institute for Molecular Life Sciences at the Goethe University explained.

With chronically infected mice as their model, the researchers used a new technology called ATAC - seq to map the regulatory regions of the genome — the sections of DNA involved in switching genes on and off — in the animals» exhausted and functional CD8 + T cells.

The answer lies in proteins, and the map of the genome does not reveal what proteins genes make to carry out their work, what the proteins do, or how the proteins interact.

«For our new systemic viral vectors — AAV PHP.S and AAV PHP.eB — there are many potential uses, from mapping circuits in the periphery and fast screening of gene regulatory elements to genome editing with powerful tools such as CRISPR - Cas9,» says Gradinaru.

«With this comprehensive catalog of mutations present in the Ashkenazi Jewish population, we will be able to more effectively map disease genes onto the genome and thus gain a better understanding of common disorders.

Uncovering the genetic pathogenesis of Alzheimer's disease has been a target of great interest over the past few years, and genome - wide mapping studies focusing on risk genes have led to significant advances in the field.

By the time the DNA sequencer made the Human Genome Project possible in the late 1990s, scientists were mapping genes at thousands of times the rate that they had done two decades before.

Using a technique called whole - genome random sequencing, a TIGR team mapped the entire two - million - gene sequence of Thermotoga maritima, a bacterium first plucked from hot geothermal springs in Vulcano, Italy.

Hubbard does not dispute this: what concerns her, rather, is that the intensified effort to «map» the human genome puts too much emphasis on genes and too little on the contexts in which they work — or in which people work.

Two groups of researchers published the first genome - wide CNV maps, which illustrated that variation in gene quantity is actually quite common: each group found about 12 copy number imbalances per person.

Geneticists speak of «mapping» the human genome, so that we know where genes «for» all kinds of things (from homosexuality to manic depression) are located; a promotional video produced by the Human Genome Project asks viewers to «imagine a map that would lead us to the richest treasure in the world», with which we will know «where... every genetic inheritance of humankind is to be found&rgenome, so that we know where genes «for» all kinds of things (from homosexuality to manic depression) are located; a promotional video produced by the Human Genome Project asks viewers to «imagine a map that would lead us to the richest treasure in the world», with which we will know «where... every genetic inheritance of humankind is to be found&rGenome Project asks viewers to «imagine a map that would lead us to the richest treasure in the world», with which we will know «where... every genetic inheritance of humankind is to be found».

Pairwise alignments were calculated using Shuffle - LAGAN (window size, 400 bp; step size 40 bp; translated anchoring), a glocal alignment algorithm that is able to calculate optimal alignments by using both local alignments and global maps of sequence rearrangements (e.g. duplications of the fiber gene in adenovirus genomes with 2 fibers)[57].

A spruce gene map infers ancient plant genome reshuffling and subsequent slow evolution in the gymnosperm lineage leading to extant conifers.

«A three - dimensional map of the genome: Gene mapping technique promises to unlock the power of proximity to find genes implicated in diseases.»

For instance, the Human Microbiome Project (HMP)(Turnbaugh et al, 2007; Peterson et al, 2009; Huttenhower et al, 2012) and MetaHIT (Qin et al, 2010) have generated maps of bacterial species abundances throughout the human body, reference genomes, and catalogs of more than 100 million microbial genes assembled from shotgun sequencing of in vivo communities.

In cancer, a state marked by increased protein translation and biomass expansion, HSF1 is activated and binds to numerous genes throughout the genome, as seen in the heat map of HSF1 ChIP - Seq read density in M0 - 91acute myeloid leukemia cells (DMSO, far leftIn cancer, a state marked by increased protein translation and biomass expansion, HSF1 is activated and binds to numerous genes throughout the genome, as seen in the heat map of HSF1 ChIP - Seq read density in M0 - 91acute myeloid leukemia cells (DMSO, far leftin the heat map of HSF1 ChIP - Seq read density in M0 - 91acute myeloid leukemia cells (DMSO, far leftin M0 - 91acute myeloid leukemia cells (DMSO, far left).

To explore the kinetics of gene selection in vivo, we plotted the percentage of sequencing reads mapped to genes in the Bt genome over time and examined genes constituting > 0.2 % of total reads.

g (acceleration due to gravity) G (gravitational constant) G star G1.9 +0.3 gabbro Gabor, Dennis (1900 — 1979) Gabriel's Horn Gacrux (Gamma Crucis) gadolinium Gagarin, Yuri Alexeyevich (1934 — 1968) Gagarin Cosmonaut Training Center GAIA Gaia Hypothesis galactic anticenter galactic bulge galactic center Galactic Club galactic coordinates galactic disk galactic empire galactic equator galactic habitable zone galactic halo galactic magnetic field galactic noise galactic plane galactic rotation galactose Galatea GALAXIES galaxy galaxy cannibalism galaxy classification galaxy formation galaxy interaction galaxy merger Galaxy, The Galaxy satellite series Gale Crater Galen (c. AD 129 — c. 216) galena GALEX (Galaxy Evolution Explorer) Galilean satellites Galilean telescope Galileo (Galilei, Galileo)(1564 — 1642) Galileo (spacecraft) Galileo Europa Mission (GEM) Galileo satellite navigation system gall gall bladder Galle, Johann Gottfried (1812 — 1910) gallic acid gallium gallon gallstone Galois, Évariste (1811 — 1832) Galois theory Galton, Francis (1822 — 1911) Galvani, Luigi (1737 — 1798) galvanizing galvanometer game game theory GAMES AND PUZZLES gamete gametophyte Gamma (Soviet orbiting telescope) Gamma Cassiopeiae Gamma Cassiopeiae star gamma function gamma globulin gamma rays Gamma Velorum gamma - ray burst gamma - ray satellites Gamow, George (1904 — 1968) ganglion gangrene Ganswindt, Hermann (1856 — 1934) Ganymede «garbage theory», of the origin of life Gardner, Martin (1914 — 2010) Garneau, Marc (1949 ---RRB- garnet Garnet Star (Mu Cephei) Garnet Star Nebula (IC 1396) garnierite Garriott, Owen K. (1930 ---RRB- Garuda gas gas chromatography gas constant gas giant gas laws gas - bounded nebula gaseous nebula gaseous propellant gaseous - propellant rocket engine gasoline Gaspra (minor planet 951) Gassendi, Pierre (1592 — 1655) gastric juice gastrin gastrocnemius gastroenteritis gastrointestinal tract gastropod gastrulation Gatewood, George D. (1940 ---RRB- Gauer - Henry reflex gauge boson gauge theory gauss (unit) Gauss, Carl Friedrich (1777 — 1855) Gaussian distribution Gay - Lussac, Joseph Louis (1778 — 1850) GCOM (Global Change Observing Mission) Geber (c. 720 — 815) gegenschein Geiger, Hans Wilhelm (1882 — 1945) Geiger - Müller counter Giessler tube gel gelatin Gelfond's theorem Gell - Mann, Murray (1929 ---RRB- GEM «gemination,» of martian canals Geminga Gemini (constellation) Gemini Observatory Gemini Project Gemini - Titan II gemstone gene gene expression gene mapping gene pool gene therapy gene transfer General Catalogue of Variable Stars (GCVS) general precession general theory of relativity generation ship generator Genesis (inflatable orbiting module) Genesis (sample return probe) genetic code genetic counseling genetic disorder genetic drift genetic engineering genetic marker genetic material genetic pool genetic recombination genetics GENETICS AND HEREDITY Geneva Extrasolar Planet Search Program genome genome, interstellar transmission of genotype gentian violet genus geoboard geode geodesic geodesy geodesy satellites geodetic precession Geographos (minor planet 1620) geography GEOGRAPHY Geo - IK geologic time geology GEOLOGY AND PLANETARY SCIENCE geomagnetic field geomagnetic storm geometric mean geometric sequence geometry GEOMETRY geometry puzzles geophysics GEOS (Geodetic Earth Orbiting Satellite) Geosat geostationary orbit geosynchronous orbit geosynchronous / geostationary transfer orbit (GTO) geosyncline Geotail (satellite) geotropism germ germ cells Germain, Sophie (1776 — 1831) German Rocket Society germanium germination Gesner, Konrad von (1516 — 1565) gestation Get Off the Earth puzzle Gettier problem geyser g - force GFO (Geosat Follow - On) GFZ - 1 (GeoForschungsZentrum) ghost crater Ghost Head Nebula (NGC 2080) ghost image Ghost of Jupiter (NGC 3242) Giacconi, Riccardo (1931 ---RRB- Giacobini - Zinner, Comet (Comet 21P /) Giaever, Ivar (1929 ---RRB- giant branch Giant Magellan Telescope giant molecular cloud giant planet giant star Giant's Causeway Giauque, William Francis (1895 — 1982) gibberellins Gibbs, Josiah Willard (1839 — 1903) Gibbs free energy Gibson, Edward G. (1936 ---RRB- Gilbert, William (1544 — 1603) gilbert (unit) Gilbreath's conjecture gilding gill gill (unit) Gilruth, Robert R. (1913 — 2000) gilsonite gimbal Ginga ginkgo Giotto (ESA Halley probe) GIRD (Gruppa Isutcheniya Reaktivnovo Dvisheniya) girder glacial drift glacial groove glacier gland Glaser, Donald Arthur (1926 — 2013) Glashow, Sheldon (1932 ---RRB- glass GLAST (Gamma - ray Large Area Space Telescope) Glauber, Johann Rudolf (1607 — 1670) glaucoma glauconite Glenn, John Herschel, Jr. (1921 ---RRB- Glenn Research Center Glennan, T (homas) Keith (1905 — 1995) glenoid cavity glia glial cell glider Gliese 229B Gliese 581 Gliese 67 (HD 10307, HIP 7918) Gliese 710 (HD 168442, HIP 89825) Gliese 86 Gliese 876 Gliese Catalogue glioma glissette glitch Global Astrometric Interferometer for Astrophysics (GAIA) Global Oscillation Network Group (GONG) Globalstar globe Globigerina globular cluster globular proteins globule globulin globus pallidus GLOMR (Global Low Orbiting Message Relay) GLONASS (Global Navigation Satellite System) glossopharyngeal nerve Gloster E. 28/39 glottis glow - worm glucagon glucocorticoid glucose glucoside gluon Glushko, Valentin Petrovitch (1908 — 1989) glutamic acid glutamine gluten gluteus maximus glycerol glycine glycogen glycol glycolysis glycoprotein glycosidic bond glycosuria glyoxysome GMS (Geosynchronous Meteorological Satellite) GMT (Greenwich Mean Time) Gnathostomata gneiss Go Go, No - go goblet cell GOCE (Gravity field and steady - state Ocean Circulation Explorer) God Goddard, Robert Hutchings (1882 — 1945) Goddard Institute for Space Studies Goddard Space Flight Center Gödel, Kurt (1906 — 1978) Gödel universe Godwin, Francis (1562 — 1633) GOES (Geostationary Operational Environmental Satellite) goethite goiter gold Gold, Thomas (1920 — 2004) Goldbach conjecture golden ratio (phi) Goldin, Daniel Saul (1940 ---RRB- gold - leaf electroscope Goldstone Tracking Facility Golgi, Camillo (1844 — 1926) Golgi apparatus Golomb, Solomon W. (1932 — 2016) golygon GOMS (Geostationary Operational Meteorological Satellite) gonad gonadotrophin - releasing hormone gonadotrophins Gondwanaland Gonets goniatite goniometer gonorrhea Goodricke, John (1764 — 1786) googol Gordian Knot Gordon, Richard Francis, Jr. (1929 — 2017) Gore, John Ellard (1845 — 1910) gorge gorilla Gorizont Gott loop Goudsmit, Samuel Abraham (1902 — 1978) Gould, Benjamin Apthorp (1824 — 1896) Gould, Stephen Jay (1941 — 2002) Gould Belt gout governor GPS (Global Positioning System) Graaf, Regnier de (1641 — 1673) Graafian follicle GRAB graben GRACE (Gravity Recovery and Climate Experiment) graceful graph gradient Graham, Ronald (1935 ---RRB- Graham, Thomas (1805 — 1869) Graham's law of diffusion Graham's number GRAIL (Gravity Recovery and Interior Laboratory) grain (cereal) grain (unit) gram gram - atom Gramme, Zénobe Théophile (1826 — 1901) gramophone Gram's stain Gran Telescopio Canarias (GTC) Granat Grand Tour grand unified theory (GUT) Grandfather Paradox Granit, Ragnar Arthur (1900 — 1991) granite granulation granule granulocyte graph graph theory graphene graphite GRAPHS AND GRAPH THEORY graptolite grass grassland gravel graveyard orbit gravimeter gravimetric analysis Gravitational Biology Facility gravitational collapse gravitational constant (G) gravitational instability gravitational lens gravitational life gravitational lock gravitational microlensing GRAVITATIONAL PHYSICS gravitational slingshot effect gravitational waves graviton gravity gravity gradient gravity gradient stabilization Gravity Probe A Gravity Probe B gravity - assist gray (Gy) gray goo gray matter grazing - incidence telescope Great Annihilator Great Attractor great circle Great Comets Great Hercules Cluster (M13, NGC 6205) Great Monad Great Observatories Great Red Spot Great Rift (in Milky Way) Great Rift Valley Great Square of Pegasus Great Wall greater omentum greatest elongation Green, George (1793 — 1841) Green, Nathaniel E. Green, Thomas Hill (1836 — 1882) green algae Green Bank Green Bank conference (1961) Green Bank Telescope green flash greenhouse effect greenhouse gases Green's theorem Greg, Percy (1836 — 1889) Gregorian calendar Grelling's paradox Griffith, George (1857 — 1906) Griffith Observatory Grignard, François Auguste Victor (1871 — 1935) Grignard reagent grike Grimaldi, Francesco Maria (1618 — 1663) Grissom, Virgil (1926 — 1967) grit gritstone Groom Lake Groombridge 34 Groombridge Catalogue gross ground, electrical ground state ground - track group group theory GROUPS AND GROUP THEORY growing season growth growth hormone growth hormone - releasing hormone growth plate Grudge, Project Gruithuisen, Franz von Paula (1774 — 1852) Grus (constellation) Grus Quartet (NGC 7552, NGC 7582, NGC 7590, and NGC 7599) GSLV (Geosynchronous Satellite Launch Vehicle) g - suit G - type asteroid Guericke, Otto von (1602 — 1686) guanine Guiana Space Centre guidance, inertial Guide Star Catalog (GSC) guided missile guided missiles, postwar development Guillaume, Charles Édouard (1861 — 1938) Gulf Stream (ocean current) Gulfstream (jet plane) Gullstrand, Allvar (1862 — 1930) gum Gum Nebula gun metal gunpowder Gurwin Gusev Crater gut Gutenberg, Johann (c. 1400 — 1468) Guy, Richard Kenneth (1916 ---RRB- guyot Guzman Prize gymnosperm gynecology gynoecium gypsum gyrocompass gyrofrequency gyropilot gyroscope gyrostabilizer Gyulbudagian's Nebula (HH215)

To this end we will implement a 3D browser to map genomic features as they really localize in the nucleus, for a better characterizing how genome architecture dynamically integrates external signals to orchestrate gene expression.

GS showed genome - wide significant slope decrease by — 3.86 (95 % CI: — 4.64 to — 3.07, p < 2 × 10 — 16) per standard deviation of the GS for 6 SNPs mapping to genes involved in neuronal development and signaling, axonal myelinization, and glutamatergic / GABA neurotransmission.

This genome map gives us a pretty comprehensive view of the genes in there.

The ENCODE maps allow researchers to inspect the chromosomes, genes, functional elements and individual nucleotides in the human genome in much the same way.»

In 1997, when few genome sequences were available, Hieter helped create XREFdb, a public database that linked the functional annotations of genes studied in model organisms with the phenotypic annotations on the human and mouse genetic mapIn 1997, when few genome sequences were available, Hieter helped create XREFdb, a public database that linked the functional annotations of genes studied in model organisms with the phenotypic annotations on the human and mouse genetic mapin model organisms with the phenotypic annotations on the human and mouse genetic maps.

To capture additional spliced reads that remained unmapped, we remapped all unmapped reads against the OGSv2 predicted transcriptome using the — very - sensitive - local option in bowtie2 [47], and added the counts of reads mapped to each gene to the counts derived from the genome mapping.

The mapping of the genome was finished in 2003, and scientists are continuing on the quest to discover what each gene does and how it functions.

In 2001, it took 15 months and 300 million dollars to map the 20,000 genes in the human genomIn 2001, it took 15 months and 300 million dollars to map the 20,000 genes in the human genomin the human genome.

This section invites manuscripts describing (a) Linkage, association, substitution or positional mapping and epigenetic studies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence variation.

Any reads that map to multiple locations in the genome (also called multireads) are not counted towards the expression estimates since they can not be assigned to any gene unambiguously, but these provide evidence of transcription in at least one of the loci to which they map.

In an interview with Seeker, lead author Michael Palmgren explained that mapping plant genomes has led to exciting new knowledge about how domestication works on the genetic level, including which specific genes were mutated to create the traits we most desire in our agricultural cropIn an interview with Seeker, lead author Michael Palmgren explained that mapping plant genomes has led to exciting new knowledge about how domestication works on the genetic level, including which specific genes were mutated to create the traits we most desire in our agricultural cropin our agricultural crops.

With funding for over a decade from the NSF and the USDA, the Rice Diversity Project supports QTL mapping, Genome Wide Association Studies (GWAS), and gene discovery using a suite of open - source genetic, genomic and bioinformatic resources developed in the McCouch lab.

An international team of scientists sequenced the genome of the California two - spot octopus — the first cephalopod ever to be fully sequenced — and mapped gene expression profiles in 12 different tissues.

In the figure: ChIA - PET genomic analyses successfully mapped condensin (left) and cohesin (right)- mediated gene contacts throughout the fission yeast genome.

NCBI provides Gene, Online Mendelian Inheritance in Man, the Molecular Modeling Database (3D protein structures), dbSNP (a database of single - nucleotide polymorphisms), the Reference Sequence Collection, a map of the human genome, and a taxonomy browser, and coordinates with the National Cancer Institute to provide the Cancer Genome Anatomy Prgenome, and a taxonomy browser, and coordinates with the National Cancer Institute to provide the Cancer Genome Anatomy PrGenome Anatomy Project.

This is similar to understanding the genome project that has been in the news that helps explain the DNA and the mapping of all genes.

Now that we have mapped the complete dog genome, genes involved in both disease and desired traits can be identified much more quickly.

In addition to specific disease research, CHF funds the gargantuan canine genome project to map the entire gene code of man's best friend.