Sentences with phrase «marked by the discovery»

But the past decade or two of research, which is marked by the discovery of thousands of specimens of early birds and flying dinosaurs, also shows that feathers were an early evolutionary innovation — even if they probably arose for reasons unrelated to powered flight, such as insulation or sexual display.

Not exact matches

When Cassini plunges into the cloud tops of Saturn later this year, it will mark the end of one of the most successful missions of discovery ever launched by humanity.

• For biologists, 1995 was a banner year, marked by the first discovery in decades of a whole new kind of animal life.

As Boodin has said, the new intellectual renaissance into which physics has led us in the twentieth century is marked, not only by the emancipation from mechanism, but «the discovery of form or structure as fundamental in reality.

This month marks the 100th anniversary of the discovery by Sir Ronald Ross that mosquitoes transmit malaria.

It builds on a 2011 discovery by Berman and Laird that first determined loss of these DNA marks — called methyl groups — occurs in specific areas of the genome in cancer.

This year marks the semicentennial of the discovery of pulsars, first observed by Jocelyn Bell Burnell, shown here in 1968 at the Mullard Radio Astronomy Observatory in Cambridge, England.

The discovery of sparticles would mark its first failure to adequately explain the tiny quantum world and would unleash an avalanche of new tests by experimental particle physicists, who sometimes deride string theory as too abstract.

The researchers, led by Yale chemistry professor Mark Johnson, report their discovery in the Dec. 1 edition of the journal Science.

The research marks a major milestone and, while a long way from clinical use, it may speed stroke discoveries by providing a better, more predictive translational model.

Dr. Jiangshan Yu at the University of Luxembourg, Professor Mark Ryan at the University of Birmingham and Professor Cas Cremers at the University of Oxford, were motivated by the discovery of mass software vulnerabilities, such as the Heartbleed bug, that make the majority of devices vulnerable to compromise.

The discovery suggests that when the rover descends into the crater in a few months, it may find a bathtub ring of the tiny concretions — an ancient high - water mark suggesting the area was altered by ground, not surface, water.

Institute Director Professor Mark von Itzstein, of the Institute for Glycomics, said research findings published in the international journal Angewandte Chemie International Edition this week offers a new direction in drug discovery for the treatment of respiratory infections caused by this virus.

The previous discovery of soft, pliable tissues recovered from the dissolved remains of Tyrannosaur bone in 2005 [1], potentially marked a major turning point in the science of paleontology given that it extended the known range of preserved biomolecules by many orders of magnitude.

This discovery and the introduction of 11 other new small habitable zone candidate planets were originally made by NASA's Kepler space telescopes and mark another milestone in the journey to finding another «Earth.»

These results mark some of the first science to come from a two - wheel - controlled Kepler spacecraft, proving the capability for unprecedented discoveries afforded by extending Kepler observations to the ecliptic.

The symposium marks the 10th anniversary of the Nobel Prize - winning discovery of induced pluripotent stem cells (iPSCs) by Yamanaka and Kazutoshi Takahashi.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Flappers» swinging silhouettes were inspired by the bold patterns that marked Art Deco and surrealism, jazz music, and Egyptian motifs (thanks to the discovery of King Tut's tomb).

Bucking the odds against a 2nd sequel delivering the excitement and discovery of a hugely successful original, and after a first sequel («Shrek 2») that outdid its predecessor by $ hundreds of millions and critical approval, Shrek the Third holds onto the cast of characters and the animated expressiveness that marks the series.

Review I have seen this movie twice, probably the third romantic movie that compelled me to do that, and the reasons are quite simple: It's probably impossible that anyone can't relate to young Josh Hutcherson's character, an 11 year old with a normal middle class life and problems (parents initiating divorce); that its surprise by the rediscovery of a young classmate (Charley Ray) initially as an unexpected friend and later as something else... The well crafted work of director Mark Levin is based on the mutual discovery of all these feelings (mostly new and uncontrolled) that evolved in Josh's character and in another particular viewer: you.

One of my favorite late-fest discoveries at Sundance 2012 was The End of Love, a film directed / written by, and starring, Mark Webber and his 2 - year - old son.

Hader's interview is marked by startling discoveries.

TRANSFORMERS: AGE OF EXTINCTION Starring: Mark Wahlerg and Nicola Peltz Directed by: Michael Bay An automobile mechanic and his daughter make a discovery that brings down the Autobots and Decepticons — and a paranoid government official — on them.

A heady topic distracted from by too many pointless discoveries of broken glasses and old bikes, none of which go anywhere in a picture marked mainly by its aimlessness.

From marketing and discovery discussions with Author Day co-sponsor (thank you) Publishers Weekly's Cevin Bryarman and Kobo's Mark Lefevbre to community and audience - creation debate with Wattpad's Allen Lau and distribution points from Net Minds» Tim Sanders, the tone and pitch of the day was rooted in responsibility — the author's responsibility to educate him - and herself, to learn to flex long - unused business muscles by understanding the business and tackling deficiencies.

Combined efforts of the dedicated Miniature Poodle breeders and the research team led by Dr. Mark Neff at the Van Andel Research Institute culminated in the discovery of a partial deletion of the sulfate transporter gene, SLC13A1, as a cause of the osteochondrodysplasia in this breed (2,3).

The water here is usually calm so it is a great choice if you're traveling with kids, and the gentle surf and reefs make it a good spot for beginning snorkelers too — a snorkel trail stretching 200 yards is marked by underwater signs to guide you on your below - the - surface discoveries.

They might include towering industrial landscapes by Edward Burtynsky with Koch and, among Discoveries, garage interiors wide open to the light by Mark Lyon or walls as visual collage by Andy Mattern, both with Elizabeth Houston.

It is the discovery of an unusual and intriguing detail (lip marks on a mirror) which leads to an investigation by the psychiatrist and an epiphany for the patient.

-- One of Rembrandt's rarest prints, Woman Sitting Half Dressed Beside a Stove (c. 1658) will be presented by David Tunick, Inc. in a newly discovered state, marking a significant discovery in Rembrandt scholarship and connoisseurship.

He was influenced in this direction by his discovery of the abstract paintings of Barnett Newman and Mark Rothko that he saw in 1959 at the Tate Gallery.

by Viktor Katona for Oilprice.com On a global level, 2015 and 2016 marked the lowest level of new conventional oil discoveries since 1952.

This dramatization of the early days in the history of Facebook is told largely through flashbacks from examination for discovery transcripts related to lawsuits between the founders of Facebook, including Mark Zuckerberg (played by Jesse Eisenberg).

While often the end of a relationships is a time marked by grief, sadness, and regret, it can also be a time of discovery, learning, and maybe even a sense of liberation.In my work as a relationship therapist, I see individual therapy clients who struggle with breakups and heartache regularly, and refocusing their energy on the lessons and potential growth during this time of grieving can be a particularly effective way to grow and learn from the experience.