This allowed us to directly compare the patterns of
marker expression in normal and induced retina, and identify cell classes on the basis of their distinctive morphology and location within the eye.
Not exact matches
Prior update Nov 19, 2016 added Sonnenburg links (elimination of microbiota - accessible carbohydrates (MACs) from the diet results
in thinner mucus, increased proximity of microbes to the epithelium, and heightened
expression of inflammatory
markers.)
These epigenetic switches and
markers in turn help switch on or off the
expression of particular genes.
Prasher and Chalfie were awarded a patent for the use of GFP as a
marker of gene
expression;
in total, it earned Prasher just a few hundred thousand dollars
in royalties over 15 years.
At a 0.2 - millimolar sucralose dose similar to the concentration found
in the blood of people with high consumption of low - calorie sweeteners — equal to four cans of diet soda per day — the researchers said they observed increased
expression of genes that are
markers of fat production and inflammation.
Their presentation is entitled «High
expression of AF1q is an adverse prognostic factor and a prediction
marker of extramedullary disease
in multiple myeloma.»
But
in the 1 September issue of the Journal of Clinical Investigation, cardiologist Michael Parmacek and his colleagues at the University of Chicago describe how they deleted two genes from the common cold virus to make it unable to cause any sniffling or fever, then replaced them with a
marker gene that turns out an easily detected protein and the SM22 promoter, which turns on
expression of genes
in smooth muscle cells that surround arteries.
Global gene
expression studies found that the LPA - treated mice shared many similar molecular
markers as those found
in humans with schizophrenia.
The results showed that, when applied, a long - term inhibition of Rho - kinase signaling increased the
expressions of chondrocyte - specific genes and differentiation
markers in human chondrosarcoma 2/8 cells.
The figure
in question is supposed to show patterns of
expression for a range of ES cell
markers in the 11 cell lines.
New
markers suggested include total mass of hemoglobin, altered
expression of genes related to red blood cell metabolism, ironomics, storage lesions, and the presence of plasticizers from blood bags
in athlete urine samples.
Researchers from BUSM and the University of Cyprus compared the
markers on the surface of the cancer cells to gene
expression profile of breast tumors deposited by researchers
in international public databases and found that a molecule named IL13RA2 (IL13R alpha2) was abundant
in metastatic or late - stage BLBC.
In the last 15 years, researchers worldwide have generated a large amount of information about the epigenome: proteins, factors and epigenetic
markers which, when bound to DNA, regulate gene
expression.
The use of cell surface
markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA
expression is a powerful new way enabling the study of small cell niches
in nongenetically modified animal models and human tissue.
Examination of gene
expression in patients with non-small cell lung cancer (NSCLC) showed the area adjacent to tumors is rich with cancer
markers.
This observation is further supported by the fact that studying alterations
in the
expression of genes also made it possible to identify persons whose levels of interleukin 6, an inflammation
marker, were reduced as their serum vitamin D levels increased.
Additionally, the researchers said they found evidence that preconception alcohol exposure increased the
expression of some inflammatory
markers in pancreatic tissue.
The accumulation of adipose tissue macrophages
in direct proportion to adipocyte size and body mass may explain the coordinated increase
in expression of genes encoding macrophage
markers observed
in our microarray
expression data.
Not only were levels of metabolic compounds different, but the
expression of certain genes involved
in metabolism was turned up, and the epigenome of the cells — molecular
markers on DNA that change gene
expression on a broader scale — was altered.
Kinetics study on
markers of the immune system by gene
expression profiling of an
in vivo heated tumor.
(G — L)
In situ hybridization of wild - type embryos injected with wild - type (G — I) or mutant ACVR1 (J — L) to detect ventral
markers eve1 (G, n = 12/12; J, n = 10/13; onset of gastrulation) and gata2 (H, n = 14/14; K, n = 15/19; mid-gastrulation) or dorsal
marker foxb1.2 (I, n = 12/12; L, n = 6/13, 7/13 showed no
expression; mid-gastrulation).
The key experiments included for replication were selected because they examine the induction of POSTN
expression in the pulmonary stromal fibroblasts and test the role of POSTN
in primary tumor formation and metastatic efficiency, which are relevant as the role of POSTN as a possible prognostic
marker and target for anticancer therapies is explored (Xu et al., 2012; Nuzzo et al., 2014).
Overexpression of wild - type ACVR1
in chick micromass cultures resulted
in expression levels of
marker genes that are comparable to those of the empty viral vector, while cells overexpressing R206H ACVR1 showed upregulation of collagen type II and aggrecan.
A short - term inhibition of Rho - kinase failed to induce extracellular matrix production
in fibroblasts or
in HCS - 2 / 8 cells, while its long - term exposure increased the
expressions of chondrocyte - specific genes and differentiation
markers, and also promoted the synthesis of sulfated glycosaminoglycans by chondrocytic cells.
In line with our in vitro data, Pkn1 — / — mice showed AKT hyperactivation, elevated NeuroD2 levels, and reduced expression of PF - PC synaptic markers during stages of PF maturation in viv
In line with our
in vitro data, Pkn1 — / — mice showed AKT hyperactivation, elevated NeuroD2 levels, and reduced expression of PF - PC synaptic markers during stages of PF maturation in viv
in vitro data, Pkn1 — / — mice showed AKT hyperactivation, elevated NeuroD2 levels, and reduced
expression of PF - PC synaptic
markers during stages of PF maturation
in viv
in vivo.
While
expression levels of all
marker genes remained almost unchanged
in wild - type ACVR1 cultures compared with the empty viral vector, the
expression profile induced by caACVR1 Q207D displayed evidence of advanced chondrogenic differentiation as shown by decreased levels of the early differentiation stage
marker collagen type II together with enhanced
expression of the later - stage
markers Ihh and collagen type X. Indian hedgehog has been shown previously to be induced by BMP signaling transmitted via the ACVR1 receptor (9).
g (acceleration due to gravity) G (gravitational constant) G star G1.9 +0.3 gabbro Gabor, Dennis (1900 — 1979) Gabriel's Horn Gacrux (Gamma Crucis) gadolinium Gagarin, Yuri Alexeyevich (1934 — 1968) Gagarin Cosmonaut Training Center GAIA Gaia Hypothesis galactic anticenter galactic bulge galactic center Galactic Club galactic coordinates galactic disk galactic empire galactic equator galactic habitable zone galactic halo galactic magnetic field galactic noise galactic plane galactic rotation galactose Galatea GALAXIES galaxy galaxy cannibalism galaxy classification galaxy formation galaxy interaction galaxy merger Galaxy, The Galaxy satellite series Gale Crater Galen (c. AD 129 — c. 216) galena GALEX (Galaxy Evolution Explorer) Galilean satellites Galilean telescope Galileo (Galilei, Galileo)(1564 — 1642) Galileo (spacecraft) Galileo Europa Mission (GEM) Galileo satellite navigation system gall gall bladder Galle, Johann Gottfried (1812 — 1910) gallic acid gallium gallon gallstone Galois, Évariste (1811 — 1832) Galois theory Galton, Francis (1822 — 1911) Galvani, Luigi (1737 — 1798) galvanizing galvanometer game game theory GAMES AND PUZZLES gamete gametophyte Gamma (Soviet orbiting telescope) Gamma Cassiopeiae Gamma Cassiopeiae star gamma function gamma globulin gamma rays Gamma Velorum gamma - ray burst gamma - ray satellites Gamow, George (1904 — 1968) ganglion gangrene Ganswindt, Hermann (1856 — 1934) Ganymede «garbage theory», of the origin of life Gardner, Martin (1914 — 2010) Garneau, Marc (1949 ---RRB- garnet Garnet Star (Mu Cephei) Garnet Star Nebula (IC 1396) garnierite Garriott, Owen K. (1930 ---RRB- Garuda gas gas chromatography gas constant gas giant gas laws gas - bounded nebula gaseous nebula gaseous propellant gaseous - propellant rocket engine gasoline Gaspra (minor planet 951) Gassendi, Pierre (1592 — 1655) gastric juice gastrin gastrocnemius gastroenteritis gastrointestinal tract gastropod gastrulation Gatewood, George D. (1940 ---RRB- Gauer - Henry reflex gauge boson gauge theory gauss (unit) Gauss, Carl Friedrich (1777 — 1855) Gaussian distribution Gay - Lussac, Joseph Louis (1778 — 1850) GCOM (Global Change Observing Mission) Geber (c. 720 — 815) gegenschein Geiger, Hans Wilhelm (1882 — 1945) Geiger - Müller counter Giessler tube gel gelatin Gelfond's theorem Gell - Mann, Murray (1929 ---RRB- GEM «gemination,» of martian canals Geminga Gemini (constellation) Gemini Observatory Gemini Project Gemini - Titan II gemstone gene gene
expression gene mapping gene pool gene therapy gene transfer General Catalogue of Variable Stars (GCVS) general precession general theory of relativity generation ship generator Genesis (inflatable orbiting module) Genesis (sample return probe) genetic code genetic counseling genetic disorder genetic drift genetic engineering genetic
marker genetic material genetic pool genetic recombination genetics GENETICS AND HEREDITY Geneva Extrasolar Planet Search Program genome genome, interstellar transmission of genotype gentian violet genus geoboard geode geodesic geodesy geodesy satellites geodetic precession Geographos (minor planet 1620) geography GEOGRAPHY Geo - IK geologic time geology GEOLOGY AND PLANETARY SCIENCE geomagnetic field geomagnetic storm geometric mean geometric sequence geometry GEOMETRY geometry puzzles geophysics GEOS (Geodetic Earth Orbiting Satellite) Geosat geostationary orbit geosynchronous orbit geosynchronous / geostationary transfer orbit (GTO) geosyncline Geotail (satellite) geotropism germ germ cells Germain, Sophie (1776 — 1831) German Rocket Society germanium germination Gesner, Konrad von (1516 — 1565) gestation Get Off the Earth puzzle Gettier problem geyser g - force GFO (Geosat Follow - On) GFZ - 1 (GeoForschungsZentrum) ghost crater Ghost Head Nebula (NGC 2080) ghost image Ghost of Jupiter (NGC 3242) Giacconi, Riccardo (1931 ---RRB- Giacobini - Zinner, Comet (Comet 21P /) Giaever, Ivar (1929 ---RRB- giant branch Giant Magellan Telescope giant molecular cloud giant planet giant star Giant's Causeway Giauque, William Francis (1895 — 1982) gibberellins Gibbs, Josiah Willard (1839 — 1903) Gibbs free energy Gibson, Edward G. (1936 ---RRB- Gilbert, William (1544 — 1603) gilbert (unit) Gilbreath's conjecture gilding gill gill (unit) Gilruth, Robert R. (1913 — 2000) gilsonite gimbal Ginga ginkgo Giotto (ESA Halley probe) GIRD (Gruppa Isutcheniya Reaktivnovo Dvisheniya) girder glacial drift glacial groove glacier gland Glaser, Donald Arthur (1926 — 2013) Glashow, Sheldon (1932 ---RRB- glass GLAST (Gamma - ray Large Area Space Telescope) Glauber, Johann Rudolf (1607 — 1670) glaucoma glauconite Glenn, John Herschel, Jr. (1921 ---RRB- Glenn Research Center Glennan, T (homas) Keith (1905 — 1995) glenoid cavity glia glial cell glider Gliese 229B Gliese 581 Gliese 67 (HD 10307, HIP 7918) Gliese 710 (HD 168442, HIP 89825) Gliese 86 Gliese 876 Gliese Catalogue glioma glissette glitch Global Astrometric Interferometer for Astrophysics (GAIA) Global Oscillation Network Group (GONG) Globalstar globe Globigerina globular cluster globular proteins globule globulin globus pallidus GLOMR (Global Low Orbiting Message Relay) GLONASS (Global Navigation Satellite System) glossopharyngeal nerve Gloster E. 28/39 glottis glow - worm glucagon glucocorticoid glucose glucoside gluon Glushko, Valentin Petrovitch (1908 — 1989) glutamic acid glutamine gluten gluteus maximus glycerol glycine glycogen glycol glycolysis glycoprotein glycosidic bond glycosuria glyoxysome GMS (Geosynchronous Meteorological Satellite) GMT (Greenwich Mean Time) Gnathostomata gneiss Go Go, No - go goblet cell GOCE (Gravity field and steady - state Ocean Circulation Explorer) God Goddard, Robert Hutchings (1882 — 1945) Goddard Institute for Space Studies Goddard Space Flight Center Gödel, Kurt (1906 — 1978) Gödel universe Godwin, Francis (1562 — 1633) GOES (Geostationary Operational Environmental Satellite) goethite goiter gold Gold, Thomas (1920 — 2004) Goldbach conjecture golden ratio (phi) Goldin, Daniel Saul (1940 ---RRB- gold - leaf electroscope Goldstone Tracking Facility Golgi, Camillo (1844 — 1926) Golgi apparatus Golomb, Solomon W. (1932 — 2016) golygon GOMS (Geostationary Operational Meteorological Satellite) gonad gonadotrophin - releasing hormone gonadotrophins Gondwanaland Gonets goniatite goniometer gonorrhea Goodricke, John (1764 — 1786) googol Gordian Knot Gordon, Richard Francis, Jr. (1929 — 2017) Gore, John Ellard (1845 — 1910) gorge gorilla Gorizont Gott loop Goudsmit, Samuel Abraham (1902 — 1978) Gould, Benjamin Apthorp (1824 — 1896) Gould, Stephen Jay (1941 — 2002) Gould Belt gout governor GPS (Global Positioning System) Graaf, Regnier de (1641 — 1673) Graafian follicle GRAB graben GRACE (Gravity Recovery and Climate Experiment) graceful graph gradient Graham, Ronald (1935 ---RRB- Graham, Thomas (1805 — 1869) Graham's law of diffusion Graham's number GRAIL (Gravity Recovery and Interior Laboratory) grain (cereal) grain (unit) gram gram - atom Gramme, Zénobe Théophile (1826 — 1901) gramophone Gram's stain Gran Telescopio Canarias (GTC) Granat Grand Tour grand unified theory (GUT) Grandfather Paradox Granit, Ragnar Arthur (1900 — 1991) granite granulation granule granulocyte graph graph theory graphene graphite GRAPHS AND GRAPH THEORY graptolite grass grassland gravel graveyard orbit gravimeter gravimetric analysis Gravitational Biology Facility gravitational collapse gravitational constant (G) gravitational instability gravitational lens gravitational life gravitational lock gravitational microlensing GRAVITATIONAL PHYSICS gravitational slingshot effect gravitational waves graviton gravity gravity gradient gravity gradient stabilization Gravity Probe A Gravity Probe B gravity - assist gray (Gy) gray goo gray matter grazing - incidence telescope Great Annihilator Great Attractor great circle Great Comets Great Hercules Cluster (M13, NGC 6205) Great Monad Great Observatories Great Red Spot Great Rift (
in Milky Way) Great Rift Valley Great Square of Pegasus Great Wall greater omentum greatest elongation Green, George (1793 — 1841) Green, Nathaniel E. Green, Thomas Hill (1836 — 1882) green algae Green Bank Green Bank conference (1961) Green Bank Telescope green flash greenhouse effect greenhouse gases Green's theorem Greg, Percy (1836 — 1889) Gregorian calendar Grelling's paradox Griffith, George (1857 — 1906) Griffith Observatory Grignard, François Auguste Victor (1871 — 1935) Grignard reagent grike Grimaldi, Francesco Maria (1618 — 1663) Grissom, Virgil (1926 — 1967) grit gritstone Groom Lake Groombridge 34 Groombridge Catalogue gross ground, electrical ground state ground - track group group theory GROUPS AND GROUP THEORY growing season growth growth hormone growth hormone - releasing hormone growth plate Grudge, Project Gruithuisen, Franz von Paula (1774 — 1852) Grus (constellation) Grus Quartet (NGC 7552, NGC 7582, NGC 7590, and NGC 7599) GSLV (Geosynchronous Satellite Launch Vehicle) g - suit G - type asteroid Guericke, Otto von (1602 — 1686) guanine Guiana Space Centre guidance, inertial Guide Star Catalog (GSC) guided missile guided missiles, postwar development Guillaume, Charles Édouard (1861 — 1938) Gulf Stream (ocean current) Gulfstream (jet plane) Gullstrand, Allvar (1862 — 1930) gum Gum Nebula gun metal gunpowder Gurwin Gusev Crater gut Gutenberg, Johann (c. 1400 — 1468) Guy, Richard Kenneth (1916 ---RRB- guyot Guzman Prize gymnosperm gynecology gynoecium gypsum gyrocompass gyrofrequency gyropilot gyroscope gyrostabilizer Gyulbudagian's Nebula (HH215)
The
expression patterns of cell class - specific
markers in mosaic retinas appeared the same
in host and donor derived regions suggesting that donor cells generated all retinal cell classes
in approximately normal ratios (Figures 5K — 5N and S2).
We are examining the effect of a maximal exercise stress test on gene
expression, metabolism, inflammatory
markers, and cytokine levels
in ME / CFS patients and healthy controls.
Expression of the Wnt inhibitor Dickkopf - 1 is required for the induction of neural
markers in mouse embryonic stem cells differentiating
in response to retinoic acid.
Current projects are investigating: 1) the
expression of inflammatory genes during ischemia and reperfusion of kidneys during urology transplantation and
in mouse models; 2) the
expression of inflammatory genes and proteins
in urine as
markers indicating the presence of rejection
in renal allografts; and 3) the role of adhesion molecules and chemokines
in directing leukocyte infiltration into organ allografts.
Interestingly, transient BIO exposure (1 — 2 hours) prompted accelerated WNT signaling
in hMSCs and stimulated the
expression of early osteogenic
markers, such as the osteogenic master - regulator Runx2.
When overexpressed together
in developing Xenopus embryos by RNA microinjection, these genes can induce eye - like structures as defined by the
expression of
markers for some retinal cell classes [7].
Aberrant
expression of TUBB3 has also been found
in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a
marker for the tendency to respond poorly to chemotherapy.
Corresponding to upregulated TRF2
expression at 80μM, stem cell
markers like CD44 and Oct4 were also observed to be upregulated
in Clonospheric HCT116 as compared to Parental HCT116 (Fig. 3a and 3b) Decreasing CD24
expression in clonospheric HCT116 was observed which correlated well with increased stem cell
expression (Fig. 3b).
Differential
expression of surface
markers in mouse bone marrow mesenchymal stromal cell subpopulations with distinct lineage commitment.
Pluripotency was maintained
in all edited clonal lines, as evidenced by the persistent
expression of the three pluripotency
markers.
One
in vitro NASH model uses a steatosis - inducing medium [8] to induce
expression of TNFα, a
marker of inflammation and fibrosis — like the physiologic response to steatosis
in progressing NAFLD.
Gata5 a potential diagnostic
marker for congenital heart disease The finding also suggests that gata5 could be a potential new diagnostic
marker for congenital heart defects, as the researchers demonstrated that gata5 regulates the
expression of a gene known as nkx2.5 which, when mutated
in humans, causes human congenital heart defects and disease.
We focus on developing computational methods and tools for (a) analyzing large - scale gene
expression data related to human cancer
in search for gene
markers and disease sub-categories, (b) identifying regulatory elements such as miRNA precursors and their targets
in whole genomes of plants and mammals, (c) building theoretical models of gene regulatory networks.
To determine whether
expression of PD - L1
in nephrectomy specimens can be used as a surrogate for
expression in the sites of metastases (and vice versa), we examined the correlation of
marker expression (mean AQUA scores for all four cores) between the matched specimens using the Pearson correlation test.
In harmony to the present suggestion, the scoring and image cytometry evaluation using immunohistochemistry of Cyclin D1 protein marker stated that the variations of protein expression in tissue sections could yield prognostic information or could be useful in determining subtle effects of curative or prevention therapies [31
In harmony to the present suggestion, the scoring and image cytometry evaluation using immunohistochemistry of Cyclin D1 protein
marker stated that the variations of protein
expression in tissue sections could yield prognostic information or could be useful in determining subtle effects of curative or prevention therapies [31
in tissue sections could yield prognostic information or could be useful
in determining subtle effects of curative or prevention therapies [31
in determining subtle effects of curative or prevention therapies [31].
«
In the preplanned biomarker analysis, the
expression of pSTAT3 detected by immunohistochemistry was both a prognostic
marker and a predictive biomarker of benefit from napabucasin,» the researchers wrote.
Also the prognostic
marker of HER2 \ neu positive
expression resulted
in 77.8 % of GII and 75 % of GIII cases.
«It may be feasible to detect
expression of satellite RNA
in the blood of patients as an early cancer
marker.»
Expression of epithelial - mesenchymal transition (EMT)- associated
markers in the total cell population and the cycling hypoxia - selected subpopulation.
Consistent with a decrease
in E-cadherin
expression, MDA - MB 231 F3 and BCM2 F3 cells had increased nuclear
expression of Snail and cytoplasmic
expression of a mesenchymal
marker vimentin (Figure 6c).
Increased
expression of Cd11b - a
marker of macrophages [38] seen with L - arginine admininistration
in WNIN / Gr - Ob rats, might be due to increased influx of inflammatory cells
in the exocrine fraction via adhesion molecules [17].
Patients with major depression, relative to controls, showed differential
expression of a large set of both anti- and pro-inflammatory
markers (including IL1α, 2, 3, 5, 8, 9, 10, 12A, 13, 15, 18, and IFNγ)
in BA10 [21], a region associated with reward processing [22].
There are 21 different subtypes of GABAergic interneurons
in the mammalian hippocampus, identified on their
expression of different
markers and their electrophysiological properties.